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Sustained microglial depletion with CSF1R inhibitor impairs parenchymal plaque development in an Alzheimer's disease model

Nature communications, 2019-08, Vol.10 (1), p.3758-21, Article 3758

2019

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Hypoxia perturbs aryl hydrocarbon receptor signaling and CYP1A1 expression induced by PCB 126 in human skin and liver-derived cell lines

Toxicology and applied pharmacology, 2014-02, Vol.274 (3), p.408-416

2014

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The introduction of wide-angle 270° laparoscopy through a novel laparoscopic camera system

Surgical endoscopy, 2022-03, Vol.36 (3), p.2151-2158

2022

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Phase Ib study of the combination of pexidartinib (PLX3397), a CSF-1R inhibitor, and paclitaxel in patients with advanced solid tumors

Therapeutic advances in medical oncology, 2019-06, Vol.11, p.1758835919854238

2019

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Exome-wide mutation profile in benzo[a]pyrene-derived post-stasis and immortal human mammary epithelial cells

Mutation research. Genetic toxicology and environmental mutagenesis, 2014-12, Vol.775-776 (C), p.48-54

2014

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Characterization of Hepatocellular Carcinoma Related Genes and Metabolites in Human Nonalcoholic Fatty Liver Disease

Digestive diseases and sciences, 2014-02, Vol.59 (2), p.365-374

2014

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Coordinate H3K9 and DNA methylation silencing of ZNFs in toxicant-induced malignant transformation

Epigenetics, 2013-10, Vol.8 (10), p.1080-1088

2013

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Complications of adjustable gastric banding

The Surgical clinics of North America, 2011-12, Vol.91 (6), p.1249

2011

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Cellular Localization of Kynurenine 3-Monooxygenase in the Brain: Challenging the Dogma

Antioxidants, 2022-02, Vol.11 (2), p.315

2022

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A phase 1/2 study of the oral FLT3 inhibitor pexidartinib in relapsed/refractory FLT3-ITD–mutant acute myeloid leukemia

Blood advances, 2020-04, Vol.4 (8), p.1711-1721

2020

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Monomethylarsonous Acid Produces Irreversible Events Resulting in Malignant Transformation of a Human Bladder Cell Line Following 12 Weeks of Low-Level Exposure

Toxicological sciences, 2010-07, Vol.116 (1), p.44-57

2010

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Agglomerates of aberrant DNA methylation are associated with toxicant-induced malignant transformation

Epigenetics, 2012-11, Vol.7 (11), p.1238-1248

2012

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Can Rural Minimally Invasive Surgery Fellowships Provide Operative Experience Similar to Urban Programs?

Journal of surgical education, 2016-09, Vol.73 (5), p.793-798

2016

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Building and maintaining a successful surgery program in rural Minnesota

The Surgical clinics of North America, 2009-12, Vol.89 (6), p.1349

2009

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ctDNA-based genomic landscape analysis to evaluate molecular brake and gatekeeper mutations in FGFR2 alterations

Journal of clinical oncology, 2023-06, Vol.41 (16_suppl), p.3049-3049

2023

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First in human (FIH) phase 1/1b study evaluating KIN-3248, a next-generation, irreversible pan-FGFR inhibitor (FGFRi), in patients (pts) with advanced urothelial carcinoma (UC) and other solid tumors harboring FGFR2 and/or FGFR3 gene alterations

Journal of clinical oncology, 2023-02, Vol.41 (6_suppl), p.TPS593-TPS593

2023

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Antitumor activity of KIN-2787, a next-generation pan-RAF inhibitor, in combination with MEK inhibition in preclinical models of human NRAS mutant melanoma

Journal of clinical oncology, 2022-06, Vol.40 (16_suppl), p.e15099-e15099

2022

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First in human (FIH) phase 1/1b study evaluating KIN-3248, a next-generation, irreversible pan-FGFR inhibitor (FGFRi), in patients (pts) with advanced cholangiocarcinoma (CCA) and other solid tumors harboring FGFR2 and/or FGFR3 gene alterations

Journal of clinical oncology, 2023-02, Vol.41 (4_suppl), p.TPS637-TPS637

2023

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The next-generation pan-RAF inhibitor, KIN-2787, is active in class II and class III BRAF mutant models

Journal of clinical oncology, 2021-05, Vol.39 (15_suppl), p.3116-3116

2021

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Experience-based expert consensus on the intra-operative usage of the Endoflip impedance planimetry system

Surgical endoscopy, 2021-06, Vol.35 (6), p.2731-2742

2021

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353 Multi-Center Randomized Trial Comparing Standard Forceps Biopsies to Wide-Area Transepithelial Sampling Brush for Finding Intestinal Metaplasia and Dysplasia in the Esophagus and Gastroesophageal Junction

The American journal of gastroenterology, 2019-10, Vol.114 (1), p.S207-S208

2019

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A novel combination regimen of BET and FLT3 inhibition for FLT3-ITD acute myeloid leukemia

Haematologica (Roma), 2021-04, Vol.106 (4), p.1022-1033

2021

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S1036 High-Definition Probe-Based Confocal Laser Endomicroscopy for the Detection of Neoplasia in Patients With Barrett's Esophagus: A Systematic Review and Meta-Analysis

The American journal of gastroenterology, 2021-10, Vol.116 (1), p.S491-S491

2021

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Activity of KIN-3248, a next-generation pan-FGFR inhibitor, against acquired FGFR-gatekeeper and molecular-brake drug resistance mutations

Journal of clinical oncology, 2022-02, Vol.40 (4_suppl), p.461-461

2022

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Sustained microglial depletion with CSF1R inhibitor impairs parenchymal plaque development in an Alzheimer's disease model

Hypoxia perturbs aryl hydrocarbon receptor signaling and CYP1A1 expression induced by PCB 126 in human skin and liver-derived cell lines

The introduction of wide-angle 270° laparoscopy through a novel laparoscopic camera system

Phase Ib study of the combination of pexidartinib (PLX3397), a CSF-1R inhibitor, and paclitaxel in patients with advanced solid tumors

Exome-wide mutation profile in benzo[a]pyrene-derived post-stasis and immortal human mammary epithelial cells

Characterization of Hepatocellular Carcinoma Related Genes and Metabolites in Human Nonalcoholic Fatty Liver Disease

Coordinate H3K9 and DNA methylation silencing of ZNFs in toxicant-induced malignant transformation

Complications of adjustable gastric banding

Association of Combination of Conformation-Specific KIT Inhibitors With Clinical Benefit in Patients With Refractory Gastrointestinal Stromal Tumors: A Phase 1b/2a Nonrandomized Clinical Trial

Cellular Localization of Kynurenine 3-Monooxygenase in the Brain: Challenging the Dogma

A phase 1/2 study of the oral FLT3 inhibitor pexidartinib in relapsed/refractory FLT3-ITD–mutant acute myeloid leukemia

Monomethylarsonous Acid Produces Irreversible Events Resulting in Malignant Transformation of a Human Bladder Cell Line Following 12 Weeks of Low-Level Exposure

Agglomerates of aberrant DNA methylation are associated with toxicant-induced malignant transformation

Can Rural Minimally Invasive Surgery Fellowships Provide Operative Experience Similar to Urban Programs?

Building and maintaining a successful surgery program in rural Minnesota

ctDNA-based genomic landscape analysis to evaluate molecular brake and gatekeeper mutations in FGFR2 alterations

First in human (FIH) phase 1/1b study evaluating KIN-3248, a next-generation, irreversible pan-FGFR inhibitor (FGFRi), in patients (pts) with advanced urothelial carcinoma (UC) and other solid tumors harboring FGFR2 and/or FGFR3 gene alterations

Antitumor activity of KIN-2787, a next-generation pan-RAF inhibitor, in combination with MEK inhibition in preclinical models of human NRAS mutant melanoma

First in human (FIH) phase 1/1b study evaluating KIN-3248, a next-generation, irreversible pan-FGFR inhibitor (FGFRi), in patients (pts) with advanced cholangiocarcinoma (CCA) and other solid tumors harboring FGFR2 and/or FGFR3 gene alterations

The next-generation pan-RAF inhibitor, KIN-2787, is active in class II and class III BRAF mutant models

Experience-based expert consensus on the intra-operative usage of the Endoflip impedance planimetry system

353 Multi-Center Randomized Trial Comparing Standard Forceps Biopsies to Wide-Area Transepithelial Sampling Brush for Finding Intestinal Metaplasia and Dysplasia in the Esophagus and Gastroesophageal Junction

A novel combination regimen of BET and FLT3 inhibition for FLT3-ITD acute myeloid leukemia

S1036 High-Definition Probe-Based Confocal Laser Endomicroscopy for the Detection of Neoplasia in Patients With Barrett's Esophagus: A Systematic Review and Meta-Analysis

Activity of KIN-3248, a next-generation pan-FGFR inhibitor, against acquired FGFR-gatekeeper and molecular-brake drug resistance mutations

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