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Abstract 11857: Benchmarking a Functional Assay to Assist Clinical Classification of Variants of Uncertain Significance in KCNH2 (Long QT Syndrome Type 2)

Circulation (New York, N.Y.), 2021-11, Vol.144 (Suppl_1)

2021

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Abstract 11153: Massively Parallel, High-Throughput Approach for Identifying Defective KCNH2 (hERG) Variants

Circulation (New York, N.Y.), 2021-11, Vol.144 (Suppl_1)

2021

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A massively parallel assay accurately discriminates between functionally normal and abnormal variants in a hotspot domain of KCNH2

American journal of human genetics, 2022-07, Vol.109 (7), p.1208-1216

2022

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High throughput measurement of hERG drug block kinetics using the CiPA dynamic protocol

Journal of pharmacological and toxicological methods, 2022-09, Vol.117, p.107192-107192, Article 107192

2022

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A calibrated functional patch-clamp assay to enhance clinical variant interpretation in KCNH2-related long QT syndrome

American journal of human genetics, 2022-07, Vol.109 (7), p.1199-1207

2022

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Heterozygous KCNH2 variant phenotyping using Flp-In HEK293 and high-throughput automated patch clamp electrophysiology

Biology methods and protocols, 2021, Vol.6 (1), p.bpab003-bpab003

2021

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Antisense oligonucleotide against GSK-3β in brain of SAMP8 mice improves learning and memory and decreases oxidative stress: Involvement of transcription factor Nrf2 and implications for Alzheimer disease

Free radical biology & medicine, 2014-02, Vol.67, p.387-395

2014

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Detecting Supermassive Black Hole-induced Binary Eccentricity Oscillations with LISA

Astrophysical journal. Letters, 2019-04, Vol.875 (2), p.L31

2019

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Isolated abnormal diffusing capacity for carbon monoxide (iso↓DLco) is associated with increased respiratory symptom burden in people with HIV infection

PloS one, 2023-07, Vol.18 (7), p.e0288803-e0288803

2023

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Hdac3 Deficiency Increases Marrow Adiposity and Induces Lipid Storage and Glucocorticoid Metabolism in Osteochondroprogenitor Cells

Journal of bone and mineral research, 2016-01, Vol.31 (1), p.116-128

2016

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Series: Public engagement with research. Part 3: Sharing power and building trust through partnering with communities in primary care research

The European journal of general practice, 2024-12, Vol.30 (1), p.2328707-2328707

2024

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Blood-brain barrier penetration of non-replicating SARS-CoV-2 and S1 variants of concern induce neuroinflammation which is accentuated in a mouse model of Alzheimer’s disease

Brain, behavior, and immunity, 2023-03, Vol.109, p.251-268

2023

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Development of Novel Antibody-Camptothecin Conjugates

Molecular cancer therapeutics, 2021-02, Vol.20 (2), p.329-339

2021

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The aquaporin-4 inhibitor AER-271 blocks acute cerebral edema and improves early outcome in a pediatric model of asphyxial cardiac arrest

Pediatric research, 2019-03, Vol.85 (4), p.511-517

2019

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Acute otitis externa: Consensus definition, diagnostic criteria and core outcome set development

PloS one, 2021-05, Vol.16 (5), p.e0251395-e0251395

2021

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Genomic reconstruction of the SARS-CoV-2 epidemic in England

Nature (London), 2021-12, Vol.600 (7889), p.506-511

2021

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Performance of a clinical and imaging-based multivariate model as decision support tool to help save unnecessary surgeries for high-risk breast lesions

Breast cancer research and treatment, 2021-01, Vol.185 (2), p.479-494

2021

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A mixed methods evaluation of a peer mentoring intervention in a UK school setting: Perspectives from mentees and mentors

Children and youth services review, 2022-01, Vol.132, p.106327, Article 106327

2022

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Patterns of usage and preferences of users for tuberculosis-related text messages and voice calls in Uganda

The international journal of tuberculosis and lung disease, 2018-05, Vol.22 (5), p.530

2018

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Testing the neurovascular hypothesis of Alzheimer's disease: LRP-1 antisense reduces blood-brain barrier clearance, increases brain levels of amyloid-beta protein, and impairs cognition

Journal of Alzheimer's disease, 2009-07, Vol.17 (3), p.553

2009

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COVID-19 due to the B.1.617.2 (Delta) variant compared to B.1.1.7 (Alpha) variant of SARS-CoV-2: a prospective observational cohort study

Scientific reports, 2022-06, Vol.12 (1), p.10904-10904, Article 10904

2022

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Isolated abnormal diffusing capacity for carbon monoxide

PloS one, 2023-07, Vol.18 (7), p.e0288803

2023

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Cognitive effects of diarrhea, malnutrition, and Entamoeba histolytica infection on school age children in Dhaka, Bangladesh

The American journal of tropical medicine and hygiene, 2006-03, Vol.74 (3), p.475

2006

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Abstract 11857: Benchmarking a Functional Assay to Assist Clinical Classification of Variants of Uncertain Significance in KCNH2 (Long QT Syndrome Type 2)

Abstract 11153: Massively Parallel, High-Throughput Approach for Identifying Defective KCNH2 (hERG) Variants

A massively parallel assay accurately discriminates between functionally normal and abnormal variants in a hotspot domain of KCNH2

High throughput measurement of hERG drug block kinetics using the CiPA dynamic protocol

A calibrated functional patch-clamp assay to enhance clinical variant interpretation in KCNH2-related long QT syndrome

Heterozygous KCNH2 variant phenotyping using Flp-In HEK293 and high-throughput automated patch clamp electrophysiology

Antisense oligonucleotide against GSK-3β in brain of SAMP8 mice improves learning and memory and decreases oxidative stress: Involvement of transcription factor Nrf2 and implications for Alzheimer disease

Detecting Supermassive Black Hole-induced Binary Eccentricity Oscillations with LISA

Isolated abnormal diffusing capacity for carbon monoxide (iso↓DLco) is associated with increased respiratory symptom burden in people with HIV infection

Hdac3 Deficiency Increases Marrow Adiposity and Induces Lipid Storage and Glucocorticoid Metabolism in Osteochondroprogenitor Cells

Sensitivity of SARS-CoV-2 B.1.1.7 to mRNA vaccine-elicited antibodies

Series: Public engagement with research. Part 3: Sharing power and building trust through partnering with communities in primary care research

Blood-brain barrier penetration of non-replicating SARS-CoV-2 and S1 variants of concern induce neuroinflammation which is accentuated in a mouse model of Alzheimer’s disease

Development of Novel Antibody-Camptothecin Conjugates

The aquaporin-4 inhibitor AER-271 blocks acute cerebral edema and improves early outcome in a pediatric model of asphyxial cardiac arrest

Acute otitis externa: Consensus definition, diagnostic criteria and core outcome set development

SARS-CoV-2 Omicron is an immune escape variant with an altered cell entry pathway

Genomic reconstruction of the SARS-CoV-2 epidemic in England

Performance of a clinical and imaging-based multivariate model as decision support tool to help save unnecessary surgeries for high-risk breast lesions

A mixed methods evaluation of a peer mentoring intervention in a UK school setting: Perspectives from mentees and mentors

Patterns of usage and preferences of users for tuberculosis-related text messages and voice calls in Uganda

Testing the neurovascular hypothesis of Alzheimer's disease: LRP-1 antisense reduces blood-brain barrier clearance, increases brain levels of amyloid-beta protein, and impairs cognition

COVID-19 due to the B.1.617.2 (Delta) variant compared to B.1.1.7 (Alpha) variant of SARS-CoV-2: a prospective observational cohort study

Isolated abnormal diffusing capacity for carbon monoxide

Cognitive effects of diarrhea, malnutrition, and Entamoeba histolytica infection on school age children in Dhaka, Bangladesh

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