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Design, synthesis, and bioassay of 4-thiazolinone derivatives as influenza neuraminidase inhibitors

European journal of medicinal chemistry, 2021-03, Vol.213, p.113161, Article 113161

2021

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Synthesis and cytotoxic studies of novel 5-phenylisatin derivatives and their anti-migration and anti-angiogenic evaluation

European journal of medicinal chemistry, 2018-08, Vol.156, p.800-814

2018

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SAR towards indoline and 3-azaindoline classes of IDO1 inhibitors

Bioorganic & medicinal chemistry letters, 2021-09, Vol.47, p.128214-128214, Article 128214

2021

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Pyrazolo[3,4-d]pyrimidine derivatives containing a Schiff base moiety as potential antiviral agents

Bioorganic & medicinal chemistry letters, 2018-09, Vol.28 (17), p.2979-2984

2018

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3,5-Dialkoxypyridine analogues of bedaquiline are potent antituberculosis agents with minimal inhibition of the hERG channel

Bioorganic & medicinal chemistry, 2019-04, Vol.27 (7), p.1292-1307

2019

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Variations in the C-unit of bedaquiline provides analogues with improved biology and pharmacology

Bioorganic & medicinal chemistry, 2020-01, Vol.28 (1), p.115213, Article 115213

2020

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Structure-based drug design: Synthesis and biological evaluation of quinazolin-4-amine derivatives as selective Aurora A kinase inhibitors

European journal of medicinal chemistry, 2018-09, Vol.157, p.1361-1375

2018

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Antimicrobial peptides: Structure, mechanism, and modification

European journal of medicinal chemistry, 2023-07, Vol.255, p.115377-115377, Article 115377

2023

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Structure activity relationships of benzyl C-region analogs of 2-(3-fluoro-4-methylsulfonamidophenyl)propanamides as potent TRPV1 antagonists

Bioorganic & medicinal chemistry, 2015-11, Vol.23 (21), p.6844-6854

2015

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Design, synthesis and anti-influenza A virus activity of novel 2,4-disubstituted quinazoline derivatives

Bioorganic & medicinal chemistry letters, 2020-06, Vol.30 (11), p.127143-127143, Article 127143

2020

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Evaluating the druggability of TrmD, a potential antibacterial target, through design and microbiological profiling of a series of potent TrmD inhibitors

Bioorganic & medicinal chemistry letters, 2023-06, Vol.90, p.129331-129331, Article 129331

2023

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Design, synthesis and biological evaluation of chalcones as reversers of P-glycoprotein-mediated multidrug resistance

European journal of medicinal chemistry, 2019-10, Vol.180, p.350-366

2019

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Design, synthesis and biological evaluation of (2S,3R,4R,5S,6R)-5-fluoro-6-(hydroxymethyl)-2-aryltetrahydro-2H-pyran-3,4-diols as potent and orally active SGLT dual inhibitors

Bioorganic & medicinal chemistry letters, 2018-11, Vol.28 (21), p.3446-3453

2018

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1,2,4-Triazole-3-thione compounds with a 4-ethyl alkyl/aryl sulfide substituent are broad-spectrum metallo-β-lactamase inhibitors with re-sensitization activity

European journal of medicinal chemistry, 2021-12, Vol.226, p.113873-113873, Article 113873

2021

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Synthesis, biological evaluation, and molecular docking analysis of phenstatin based indole linked chalcones as anticancer agents and tubulin polymerization inhibitors

Bioorganic chemistry, 2020-12, Vol.105, p.104447, Article 104447

2020

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N-sulfonyl peptide-hybrids as a new class of dengue virus protease inhibitors

European journal of medicinal chemistry, 2023-05, Vol.251, p.115227-115227, Article 115227

2023

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Synthesis and anticancer activity of novel bisindolylhydroxymaleimide derivatives with potent GSK-3 kinase inhibition

Bioorganic & medicinal chemistry, 2018-08, Vol.26 (14), p.4209-4224

2018

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Synthesis and antimicrobial studies of hydrazone derivatives of 4-[3-(2,4-difluorophenyl)-4-formyl-1H-pyrazol-1-yl]benzoic acid and 4-[3-(3,4-difluorophenyl)-4-formyl-1H-pyrazol-1-yl]benzoic acid

Bioorganic & medicinal chemistry letters, 2018-09, Vol.28 (17), p.2914-2919

2018

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Cytotoxic and NF-κB and mitochondrial transmembrane potential inhibitory pentacyclic triterpenoids from Syzygium corticosum and their semi-synthetic derivatives

Bioorganic & medicinal chemistry, 2018-08, Vol.26 (15), p.4452-4460

2018

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Chemical structure of hydrolysates of cereulide and their time course profile

Bioorganic & medicinal chemistry letters, 2020-05, Vol.30 (9), p.127050-127050, Article 127050

2020

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Synthesis and biological evaluation of clovamide analogues as potent anti-neuroinflammatory agents in vitro and in vivo

European journal of medicinal chemistry, 2018-05, Vol.151, p.261-271

2018

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Structure-activity relationships for unit C pyridyl analogues of the tuberculosis drug bedaquiline

Bioorganic & medicinal chemistry, 2019-04, Vol.27 (7), p.1283-1291

2019

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Development of pyrimidone D1 dopamine receptor positive allosteric modulators

Bioorganic & medicinal chemistry letters, 2021-01, Vol.31, p.127696-127696, Article 127696

2021

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Discovery of macrocyclic HDACs 1, 2, and 3 selective inhibitors for HIV latency reactivation

Bioorganic & medicinal chemistry letters, 2021-09, Vol.47, p.128168-128168, Article 128168

2021

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Syntheses, antiviral activities and induced resistance mechanisms of novel quinazoline derivatives containing a dithioacetal moiety

Bioorganic chemistry, 2018-10, Vol.80, p.433-443

2018

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Design, synthesis, and bioassay of 4-thiazolinone derivatives as influenza neuraminidase inhibitors

Synthesis and cytotoxic studies of novel 5-phenylisatin derivatives and their anti-migration and anti-angiogenic evaluation

SAR towards indoline and 3-azaindoline classes of IDO1 inhibitors

Pyrazolo[3,4-d]pyrimidine derivatives containing a Schiff base moiety as potential antiviral agents

3,5-Dialkoxypyridine analogues of bedaquiline are potent antituberculosis agents with minimal inhibition of the hERG channel

Variations in the C-unit of bedaquiline provides analogues with improved biology and pharmacology

Structure-based drug design: Synthesis and biological evaluation of quinazolin-4-amine derivatives as selective Aurora A kinase inhibitors

Antimicrobial peptides: Structure, mechanism, and modification

Structure activity relationships of benzyl C-region analogs of 2-(3-fluoro-4-methylsulfonamidophenyl)propanamides as potent TRPV1 antagonists

Design, synthesis and anti-influenza A virus activity of novel 2,4-disubstituted quinazoline derivatives

Evaluating the druggability of TrmD, a potential antibacterial target, through design and microbiological profiling of a series of potent TrmD inhibitors

Design, synthesis and biological evaluation of chalcones as reversers of P-glycoprotein-mediated multidrug resistance

Design, synthesis and biological evaluation of (2S,3R,4R,5S,6R)-5-fluoro-6-(hydroxymethyl)-2-aryltetrahydro-2H-pyran-3,4-diols as potent and orally active SGLT dual inhibitors

1,2,4-Triazole-3-thione compounds with a 4-ethyl alkyl/aryl sulfide substituent are broad-spectrum metallo-β-lactamase inhibitors with re-sensitization activity

Synthesis, biological evaluation, and molecular docking analysis of phenstatin based indole linked chalcones as anticancer agents and tubulin polymerization inhibitors

N-sulfonyl peptide-hybrids as a new class of dengue virus protease inhibitors

Synthesis and anticancer activity of novel bisindolylhydroxymaleimide derivatives with potent GSK-3 kinase inhibition

Synthesis and antimicrobial studies of hydrazone derivatives of 4-[3-(2,4-difluorophenyl)-4-formyl-1H-pyrazol-1-yl]benzoic acid and 4-[3-(3,4-difluorophenyl)-4-formyl-1H-pyrazol-1-yl]benzoic acid

Cytotoxic and NF-κB and mitochondrial transmembrane potential inhibitory pentacyclic triterpenoids from Syzygium corticosum and their semi-synthetic derivatives

Chemical structure of hydrolysates of cereulide and their time course profile

Synthesis and biological evaluation of clovamide analogues as potent anti-neuroinflammatory agents in vitro and in vivo

Structure-activity relationships for unit C pyridyl analogues of the tuberculosis drug bedaquiline

Development of pyrimidone D1 dopamine receptor positive allosteric modulators

Discovery of macrocyclic HDACs 1, 2, and 3 selective inhibitors for HIV latency reactivation

Syntheses, antiviral activities and induced resistance mechanisms of novel quinazoline derivatives containing a dithioacetal moiety

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