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Functional role of Kv1.1 and Kv1.3 channels in the neoplastic progression steps of three cancer cell lines, elucidated by scorpion peptides

International journal of biological macromolecules, 2018-05, Vol.111, p.1146-1155

2018

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Dromedary immune response and specific Kv2.1 antibody generation using a specific immunization approach

International journal of biological macromolecules, 2016-12, Vol.93 (Pt A), p.167-171

2016

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Investigating cardiotoxicity related with hERG channel blockers using molecular fingerprints and graph attention mechanism

Computers in biology and medicine, 2023-02, Vol.153, p.106464, Article 106464

2023

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Computational investigations of hERG channel blockers: New insights and current predictive models

Advanced drug delivery reviews, 2015-06, Vol.86, p.72-82

2015

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What do we not know about mitochondrial potassium channels?

Biochimica et biophysica acta, 2016-08, Vol.1857 (8), p.1247-1257

2016

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Atrial fibrillation: Therapeutic potential of atrial K + channel blockers

Pharmacology & therapeutics (Oxford), 2017-08, Vol.176, p.13-21

2017

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Venom-derived peptide inhibitors of voltage-gated potassium channels

Neuropharmacology, 2017-12, Vol.127, p.124-138

2017

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3,5-Dialkoxypyridine analogues of bedaquiline are potent antituberculosis agents with minimal inhibition of the hERG channel

Bioorganic & medicinal chemistry, 2019-04, Vol.27 (7), p.1292-1307

2019

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A novel isoquinoline alkaloid HJ-69 isolated from Zanthoxylum bungeanum attenuates inflammatory pain by inhibiting voltage-gated sodium and potassium channels

Journal of ethnopharmacology, 2024-08, Vol.330, p.118218-118218, Article 118218

2024

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Towards a Structural View of Drug Binding to hERG K+ Channels

Trends in pharmacological sciences (Regular ed.), 2017-10, Vol.38 (10), p.899-907

2017

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Ions and blockers in potassium channels: insights from free energy simulations

Biochimica et biophysica acta, 2005-02, Vol.1747 (1), p.109-120

2005

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Phenytoin and phenobarbital inhibit human HERG potassium channels

Epilepsy research, 2003, Vol.55 (1), p.147-157

2003

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Nuciferine analogs block voltage-gated sodium, calcium and potassium channels to regulate the action potential and treat arrhythmia

Biomedicine & pharmacotherapy, 2024-10, Vol.179, p.117422, Article 117422

2024

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Virtual screening of DrugBank database for hERG blockers using topological Laplacian-assisted AI models

Computers in biology and medicine, 2023-02, Vol.153, p.106491, Article 106491

2023

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Inhibition of voltage-gated potassium channel by aripiprazole in rabbit coronary arterial smooth muscle cells

European journal of pharmacology, 2024-06, Vol.973, p.176610-176610, Article 176610

2024

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Potassium channel blockers in multiple sclerosis: neuronal Kv channels and effects of symptomatic treatment

Pharmacology & therapeutics (Oxford), 2006-07, Vol.111 (1), p.224-259

2006

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An evaluation of 30 clinical drugs against the comprehensive in vitro proarrhythmia assay (CiPA) proposed ion channel panel

Journal of pharmacological and toxicological methods, 2016-09, Vol.81 (C), p.251-262

2016

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Subunit-specific inhibition of BK channels by piperine

Biophysical journal, 2024-07, Vol.123 (14), p.1942-1953

2024

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Prolonged immunomodulation in inflammatory arthritis using the selective Kv1.3 channel blocker HsTX1[R14A] and its PEGylated analog

Clinical immunology (Orlando, Fla.), 2017-07, Vol.180, p.45-57

2017

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Methotrexate, a small molecular scaffold targeting Kv1.3 channel extracellular pore region

Biochemical and biophysical research communications, 2020-11, Vol.532 (2), p.265-270

2020

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sVmKTx, a transcriptome analysis-based synthetic peptide analogue of Vm24, inhibits Kv1.3 channels of human T cells with improved selectivity

Biochemical pharmacology, 2022-05, Vol.199, p.115023-115023, Article 115023

2022

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Identification of potassium and calcium channel inhibitors as modulators of polyomavirus endosomal trafficking

Antiviral research, 2020-07, Vol.179, p.104819-104819, Article 104819

2020

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Structure-activity relationships for unit C pyridyl analogues of the tuberculosis drug bedaquiline

Bioorganic & medicinal chemistry, 2019-04, Vol.27 (7), p.1283-1291

2019

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Anti-proliferative effect of Kv1.3 blockers in A549 human lung adenocarcinoma in vitro and in vivo

European journal of pharmacology, 2011-01, Vol.651 (1-3), p.26-32

2011

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Functional role of Kv1.1 and Kv1.3 channels in the neoplastic progression steps of three cancer cell lines, elucidated by scorpion peptides

Dromedary immune response and specific Kv2.1 antibody generation using a specific immunization approach

Investigating cardiotoxicity related with hERG channel blockers using molecular fingerprints and graph attention mechanism

Direct Pharmacological Targeting of a Mitochondrial Ion Channel Selectively Kills Tumor Cells In Vivo

Computational investigations of hERG channel blockers: New insights and current predictive models

What do we not know about mitochondrial potassium channels?

Atrial fibrillation: Therapeutic potential of atrial K + channel blockers

Venom-derived peptide inhibitors of voltage-gated potassium channels

3,5-Dialkoxypyridine analogues of bedaquiline are potent antituberculosis agents with minimal inhibition of the hERG channel

A novel isoquinoline alkaloid HJ-69 isolated from Zanthoxylum bungeanum attenuates inflammatory pain by inhibiting voltage-gated sodium and potassium channels

Towards a Structural View of Drug Binding to hERG K+ Channels

Ions and blockers in potassium channels: insights from free energy simulations

Phenytoin and phenobarbital inhibit human HERG potassium channels

Nuciferine analogs block voltage-gated sodium, calcium and potassium channels to regulate the action potential and treat arrhythmia

Virtual screening of DrugBank database for hERG blockers using topological Laplacian-assisted AI models

Inhibition of voltage-gated potassium channel by aripiprazole in rabbit coronary arterial smooth muscle cells

Potassium channel blockers in multiple sclerosis: neuronal Kv channels and effects of symptomatic treatment

An evaluation of 30 clinical drugs against the comprehensive in vitro proarrhythmia assay (CiPA) proposed ion channel panel

Subunit-specific inhibition of BK channels by piperine

Prolonged immunomodulation in inflammatory arthritis using the selective Kv1.3 channel blocker HsTX1[R14A] and its PEGylated analog

Methotrexate, a small molecular scaffold targeting Kv1.3 channel extracellular pore region

sVmKTx, a transcriptome analysis-based synthetic peptide analogue of Vm24, inhibits Kv1.3 channels of human T cells with improved selectivity

Identification of potassium and calcium channel inhibitors as modulators of polyomavirus endosomal trafficking

Structure-activity relationships for unit C pyridyl analogues of the tuberculosis drug bedaquiline

Anti-proliferative effect of Kv1.3 blockers in A549 human lung adenocarcinoma in vitro and in vivo

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