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Antibodies and venom peptides: new modalities for ion channels

Nature reviews. Drug discovery, 2019-05, Vol.18 (5), p.339-357

2019

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Rearrangement of a unique Kv1.3 selectivity filter conformation upon binding of a drug

Proceedings of the National Academy of Sciences - PNAS, 2022-02, Vol.119 (5)

2022

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International Union of Basic and Clinical Pharmacology. C. Nomenclature and Properties of Calcium-Activated and Sodium-Activated Potassium Channels

Pharmacological reviews, 2017-01, Vol.69 (1), p.1-11

2017

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International Union of Pharmacology. LIII. Nomenclature and molecular relationships of voltage-gated potassium channels

Pharmacological reviews, 2005-12, Vol.57 (4), p.473

2005

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Structure of the voltage-gated potassium channel KV1.3: Insights into the inactivated conformation and binding to therapeutic leads

Channels (Austin, Tex.), 2023-12, Vol.17 (1), p.2253104-2253104

2023

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International Union of Pharmacology. LII. Nomenclature and molecular relationships of calcium-activated potassium channels

Pharmacological reviews, 2005-12, Vol.57 (4), p.463

2005

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Obstacles for T-lymphocytes in the tumour microenvironment: Therapeutic challenges, advances and opportunities beyond immune checkpoint

EBioMedicine, 2022-09, Vol.83, p.104216-104216, Article 104216

2022

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Development of a sea anemone toxin as an immunomodulator for therapy of autoimmune diseases

Toxicon (Oxford), 2012-03, Vol.59 (4), p.529-546

2012

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Mechanisms Underlying C-type Inactivation in Kv Channels: Lessons From Structures of Human Kv1.3 and Fly Shaker-IR Channels

Frontiers in pharmacology, 2022-06, Vol.13, p.924289-924289

2022

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K + channels as targets for specific immunomodulation

Trends in pharmacological sciences (Regular ed.), 2004-05, Vol.25 (5), p.280-289

2004

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Kv1.3 Channels Are a Therapeutic Target for T Cell-Mediated Autoimmune Diseases

Proceedings of the National Academy of Sciences - PNAS, 2006-11, Vol.103 (46), p.17414-17419

2006

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CD4 + T Cells Mediate the Development of Liver Fibrosis in High Fat Diet-Induced NAFLD in Humanized Mice

Frontiers in immunology, 2020-09, Vol.11, p.580968-580968

2020

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Genetics and the environment converge to dysregulate N-glycosylation in multiple sclerosis

Nature communications, 2011-05, Vol.2 (1), p.334, Article 334

2011

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Domain structure and function of matrix metalloprotease 23 (MMP23): role in potassium channel trafficking

Cellular and molecular life sciences : CMLS, 2014-04, Vol.71 (7), p.1191-1210

2014

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Shaker-related potassium channels in the central medial nucleus of the thalamus are important molecular targets for arousal suppression by volatile general anesthetics

The Journal of neuroscience, 2013-10, Vol.33 (41), p.16310-16322

2013

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The intermediate-conductance calcium-activated potassium channel KCa3.1 contributes to atherogenesis in mice and humans

The Journal of clinical investigation, 2008-09, Vol.118 (9), p.3025-3037

2008

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A Chronic Autoimmune Dry Eye Rat Model with Increase in Effector Memory T Cells in Eyeball Tissue

Journal of visualized experiments, 2017-06 (124)

2017

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Selective Kv1.3 channel blocker as therapeutic for obesity and insulin resistance

Proceedings of the National Academy of Sciences - PNAS, 2013-06, Vol.110 (24), p.E2239-E2248

2013

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Modulation of voltage-gated K⁺ channels by the sodium channel β1 subunit

Proceedings of the National Academy of Sciences - PNAS, 2012-11, Vol.109 (45), p.18577-18582

2012

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Targeting Effector Memory T Cells with a Selective Peptide Inhibitor of Kv1.3 Channels for Therapy of Autoimmune Diseases

Molecular pharmacology, 2005-04, Vol.67 (4), p.1369-1381

2005

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Structures of wild-type and H451N mutant human lymphocyte potassium channel KV1.3

Cell discovery, 2021-06, Vol.7 (1), p.39-39, Article 39

2021

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Potassium Channel Modulation by a Toxin Domain in Matrix Metalloprotease 23

The Journal of biological chemistry, 2010-03, Vol.285 (12), p.9124-9136

2010

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functional network of ion channels in T lymphocytes

Immunological reviews, 2009-09, Vol.231 (1), p.59-87

2009

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Kv1.3 Channel Up-Regulation in Peripheral Blood T Lymphocytes of Patients With Multiple Sclerosis

Frontiers in pharmacology, 2021-09, Vol.12, p.714841-714841

2021

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Antibodies and venom peptides: new modalities for ion channels

Rearrangement of a unique Kv1.3 selectivity filter conformation upon binding of a drug

International Union of Basic and Clinical Pharmacology. C. Nomenclature and Properties of Calcium-Activated and Sodium-Activated Potassium Channels

International Union of Pharmacology. LIII. Nomenclature and molecular relationships of voltage-gated potassium channels

Structure of the voltage-gated potassium channel KV1.3: Insights into the inactivated conformation and binding to therapeutic leads

International Union of Pharmacology. LII. Nomenclature and molecular relationships of calcium-activated potassium channels

Obstacles for T-lymphocytes in the tumour microenvironment: Therapeutic challenges, advances and opportunities beyond immune checkpoint

Development of a sea anemone toxin as an immunomodulator for therapy of autoimmune diseases

Mechanisms Underlying C-type Inactivation in Kv Channels: Lessons From Structures of Human Kv1.3 and Fly Shaker-IR Channels

K + channels as targets for specific immunomodulation

Kv1.3 Channels Are a Therapeutic Target for T Cell-Mediated Autoimmune Diseases

CD4 + T Cells Mediate the Development of Liver Fibrosis in High Fat Diet-Induced NAFLD in Humanized Mice

Genetics and the environment converge to dysregulate N-glycosylation in multiple sclerosis

Domain structure and function of matrix metalloprotease 23 (MMP23): role in potassium channel trafficking

Shaker-related potassium channels in the central medial nucleus of the thalamus are important molecular targets for arousal suppression by volatile general anesthetics

Spatially-resolved transcriptomics reveal macrophage heterogeneity and prognostic significance in diffuse large B-cell lymphoma

The intermediate-conductance calcium-activated potassium channel KCa3.1 contributes to atherogenesis in mice and humans

A Chronic Autoimmune Dry Eye Rat Model with Increase in Effector Memory T Cells in Eyeball Tissue

Selective Kv1.3 channel blocker as therapeutic for obesity and insulin resistance

Modulation of voltage-gated K⁺ channels by the sodium channel β1 subunit

Targeting Effector Memory T Cells with a Selective Peptide Inhibitor of Kv1.3 Channels for Therapy of Autoimmune Diseases

Structures of wild-type and H451N mutant human lymphocyte potassium channel KV1.3

Potassium Channel Modulation by a Toxin Domain in Matrix Metalloprotease 23

functional network of ion channels in T lymphocytes

Kv1.3 Channel Up-Regulation in Peripheral Blood T Lymphocytes of Patients With Multiple Sclerosis

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