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iPSC-Cardiomyocyte Models of Brugada Syndrome-Achievements, Challenges and Future Perspectives

International journal of molecular sciences, 2021-03, Vol.22 (6), p.2825

2021

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Constitutive, Basal, and β-Alanine-Mediated Activation of the Human Mas-Related G Protein-Coupled Receptor D Induces Release of the Inflammatory Cytokine IL-6 and Is Dependent on NF-κB Signaling

International journal of molecular sciences, 2021-12, Vol.22 (24), p.13254

2021

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Modulation of Closed-State Inactivation in Kv2.1/Kv6.4 Heterotetramers as Mechanism for 4-AP Induced Potentiation

PloS one, 2015-10, Vol.10 (10), p.e0141349-e0141349

2015

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Developmental Toxicity and Biotransformation of Two Anti-Epileptics in Zebrafish Embryos and Early Larvae

International journal of molecular sciences, 2021-11, Vol.22 (23), p.12696

2021

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Clinical and functional characterisation of a recurrent KCNQ1 variant in the Belgian population

Orphanet journal of rare diseases, 2023-01, Vol.18 (1), p.23-23, Article 23

2023

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Properties of Deactivation Gating Currents in Shaker Channels

Biophysical journal, 2011-03, Vol.100 (5), p.L28-L30

2011

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Hydrophobic Drug/Toxin Binding Sites in Voltage-Dependent K+ and Na+ Channels

Frontiers in pharmacology, 2020-05, Vol.11, p.735-735

2020

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A Possible Explanation for the Low Penetrance of Pathogenic KCNE1 Variants in Long QT Syndrome Type 5

Pharmaceuticals (Basel, Switzerland), 2022-12, Vol.15 (12), p.1550

2022

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Being flexible: the voltage-controllable activation gate of kv channels

Frontiers in pharmacology, 2012-01, Vol.3, p.168-168

2012

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Correction: Gubič et al. Design of New Potent and Selective Thiophene-Based KV1.3 Inhibitors and Their Potential for Anticancer Activity. Cancers 2022, 14, 2595

Cancers, 2023-05, Vol.15 (11), p.2925

2023

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Design of New Potent and Selective Thiophene-Based KV1.3 Inhibitors and Their Potential for Anticancer Activity

Cancers, 2022-05, Vol.14 (11), p.2595

2022

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The ladder-shaped polyether toxin gambierol anchors the gating machinery of Kv3.1 channels in the resting state

The Journal of general physiology, 2013-03, Vol.141 (3), p.359-369

2013

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Pharmacological Profile of the Sodium Current in Human Stem Cell-Derived Cardiomyocytes Compares to Heterologous Nav1.5+β1 Model

Frontiers in pharmacology, 2019, Vol.10, p.1374-1374

2019

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The electrically silent Kv6.4 subunit confers hyperpolarized gating charge movement in Kv2.1/Kv6.4 heterotetrameric channels

PloS one, 2012-05, Vol.7 (5), p.e37143-e37143

2012

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Morpho-functional comparison of differentiation protocols to create iPSC-derived cardiomyocytes

Biology open, 2022-02, Vol.11 (2)

2022

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Kv channel gating requires a compatible S4-S5 linker and bottom part of S6, constrained by non-interacting residues

The Journal of general physiology, 2008-12, Vol.132 (6), p.667-680

2008

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A Polyether Biotoxin Binding Site on the Lipid-Exposed Face of the Pore Domain of KV Channels Revealed by the Marine Toxin Gambierol

Proceedings of the National Academy of Sciences - PNAS, 2009-06, Vol.106 (24), p.9896-9901

2009

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Determining the correct stoichiometry of Kv2.1/Kv6.4 heterotetramers, functional in multiple stoichiometrical configurations

Proceedings of the National Academy of Sciences - PNAS, 2020-04, Vol.117 (17), p.9365-9376

2020

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Inverted allosteric coupling between activation and inactivation gates in K⁺ channels

Proceedings of the National Academy of Sciences - PNAS, 2018-05, Vol.115 (21), p.5426-5431

2018

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Phosphatidylinositol-4,5-Bisphosphate (PIP2) Stabilizes the Open Pore Conformation of the Kv11.1 (hERG) Channel

Biophysical journal, 2010-08, Vol.99 (4), p.1110-1118

2010

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Compound Heterozygous SCN5A Mutations in Severe Sodium Channelopathy With Brugada Syndrome: A Case Report

Frontiers in cardiovascular medicine, 2020-07, Vol.7

2020

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Role of the S6 C-terminus in KCNQ1 channel gating

The Journal of physiology, 2007-12, Vol.585 (2), p.325-337

2007

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REPLY TO PISUPATI ET AL: Evaluating single subunit counting data to find the correct stoichiometry

Proceedings of the National Academy of Sciences - PNAS, 2020-11, Vol.117 (47), p.29290-29291

2020

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The Selectivity Filter Is Involved in the U-Type Inactivation Process of Kv2.1 and Kv3.1 Channels

Biophysical journal, 2020-05, Vol.118 (10), p.2612-2620

2020

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Gating of Shaker-type Channels Requires the Flexibility of S6 Caused by Prolines

The Journal of biological chemistry, 2003-12, Vol.278 (50), p.50724-50731

2003

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iPSC-Cardiomyocyte Models of Brugada Syndrome-Achievements, Challenges and Future Perspectives

Constitutive, Basal, and β-Alanine-Mediated Activation of the Human Mas-Related G Protein-Coupled Receptor D Induces Release of the Inflammatory Cytokine IL-6 and Is Dependent on NF-κB Signaling

Modulation of Closed-State Inactivation in Kv2.1/Kv6.4 Heterotetramers as Mechanism for 4-AP Induced Potentiation

Developmental Toxicity and Biotransformation of Two Anti-Epileptics in Zebrafish Embryos and Early Larvae

Clinical and functional characterisation of a recurrent KCNQ1 variant in the Belgian population

Properties of Deactivation Gating Currents in Shaker Channels

Hydrophobic Drug/Toxin Binding Sites in Voltage-Dependent K+ and Na+ Channels

A Possible Explanation for the Low Penetrance of Pathogenic KCNE1 Variants in Long QT Syndrome Type 5

Being flexible: the voltage-controllable activation gate of kv channels

Correction: Gubič et al. Design of New Potent and Selective Thiophene-Based KV1.3 Inhibitors and Their Potential for Anticancer Activity. Cancers 2022, 14, 2595

Design of New Potent and Selective Thiophene-Based KV1.3 Inhibitors and Their Potential for Anticancer Activity

The ladder-shaped polyether toxin gambierol anchors the gating machinery of Kv3.1 channels in the resting state

Pharmacological Profile of the Sodium Current in Human Stem Cell-Derived Cardiomyocytes Compares to Heterologous Nav1.5+β1 Model

The electrically silent Kv6.4 subunit confers hyperpolarized gating charge movement in Kv2.1/Kv6.4 heterotetrameric channels

Morpho-functional comparison of differentiation protocols to create iPSC-derived cardiomyocytes

Kv channel gating requires a compatible S4-S5 linker and bottom part of S6, constrained by non-interacting residues

A Polyether Biotoxin Binding Site on the Lipid-Exposed Face of the Pore Domain of KV Channels Revealed by the Marine Toxin Gambierol

Determining the correct stoichiometry of Kv2.1/Kv6.4 heterotetramers, functional in multiple stoichiometrical configurations

Inverted allosteric coupling between activation and inactivation gates in K⁺ channels

Phosphatidylinositol-4,5-Bisphosphate (PIP2) Stabilizes the Open Pore Conformation of the Kv11.1 (hERG) Channel

Compound Heterozygous SCN5A Mutations in Severe Sodium Channelopathy With Brugada Syndrome: A Case Report

Role of the S6 C-terminus in KCNQ1 channel gating

REPLY TO PISUPATI ET AL: Evaluating single subunit counting data to find the correct stoichiometry

The Selectivity Filter Is Involved in the U-Type Inactivation Process of Kv2.1 and Kv3.1 Channels

Gating of Shaker-type Channels Requires the Flexibility of S6 Caused by Prolines

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