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Embryonic cardiac arrhythmia and generation of reactive oxygen species: Common teratogenic mechanism for IKr blocking drugs

Reproductive toxicology (Elmsford, N.Y.), 2007-07, Vol.24 (1), p.42-56

2007

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Is erythromycin therapy teratogenic in humans?

Reproductive toxicology (Elmsford, N.Y.), 2005-07, Vol.20 (2), p.209-214

2005

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Effects of the antiepileptic drugs lamotrigine, topiramate and gabapentin on hERG potassium currents

Epilepsy research, 2005, Vol.63 (1), p.17-25

2005

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Fetal safety of erythromycin. An update of Swedish data

European journal of clinical pharmacology, 2014-03, Vol.70 (3), p.355-360

2014

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Embryonic Arrhythmia by Inhibition of HERG Channels: A Common Hypoxia‐related Teratogenic Mechanism for Antiepileptic Drugs?

Epilepsia (Copenhagen), 2002-05, Vol.43 (5), p.457-468

2002

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Maternal toxicity

Methods in molecular biology (Clifton, N.J.), 2013, Vol.947, p.311

Danielsson, Bengt R

2013

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Teratogenicity by the hERG potassium channel blocking drug almokalant: use of hypoxia marker gives evidence for a hypoxia-related mechanism mediated via embryonic arrhythmia

Toxicology and applied pharmacology, 2003-12, Vol.193 (2), p.168-176

2003

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Increased Susceptibility to Phenytoin Teratogenicity: Excessive Generation of Reactive Oxygen Species or Impaired Antioxidant Defense?

Basic & clinical pharmacology & toxicology, 2006-10, Vol.99 (4), p.305-311

2006

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Phenytoin teratogenicity: Hypoxia marker and effects on embryonic heart rhythm suggest an hERG-related mechanism

Birth defects research. A Clinical and molecular teratology, 2005-03, Vol.73 (3), p.146-153

2005

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ILSI/HESI maternal toxicity workshop summary: maternal toxicity and its impact on study design and data interpretation

Birth defects research. Part B, Developmental and reproductive toxicology, 2011-02, Vol.92 (1), p.36-51

2011

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Phenytoin and phenobarbital inhibit human HERG potassium channels

Epilepsy research, 2003-06, Vol.55 (1), p.147-157

2003

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New proposals for testing drugs with IKr-blocking activity to determine their teratogenic potential

Current pharmaceutical design, 2007-10, Vol.13 (29), p.2979

2007

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Polytherapy with hERG-blocking antiepileptic drugs: Increased risk for embryonic cardiac arrhythmia and teratogenicity

Birth defects research. A Clinical and molecular teratology, 2007-08, Vol.79 (8), p.595-603

2007

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Teratogenicity of the IKr-blocker cisapride: relation to embryonic cardiac arrhythmia

Reproductive toxicology (Elmsford, N.Y.), 2002, Vol.16 (4), p.333-342

2002

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Teratogenicity of the class III antiarrhythmic drug almokalant. Role of hypoxia and reactive oxygen species

Reproductive toxicology (Elmsford, N.Y.), 1999-03, Vol.13 (2), p.93-101

1999

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Exaggerated pharmacology versus true toxicity—Part 1

Reproductive toxicology (Elmsford, N.Y.), 2009-09, Vol.28 (2), p.140-140

Danielsson, Bengt R.

2009

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Phenytoin-induced cleft palate: Evidence for embryonic cardiac bradyarrhythmia due to inhibition of delayed rectifier k+ channels resulting in hypoxia-reoxygenation damage

Teratology (Philadelphia), 2001-03, Vol.63 (3), p.152-160

2001

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Improved methodology for identifying the teratogenic potential in early drug development of hERG channel blocking drugs

Reproductive toxicology (Elmsford, N.Y.), 2010-04, Vol.29 (2), p.156-163

2010

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Polytherapy with hERG-blocking antiepileptic drugs: Increased risk for embryonic cardiac arrhythmia and teratogenicity

Birth defects research. A Clinical and molecular teratology, 2007-08, Vol.79 (8), p.595-603

2007

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Fully Automatic Heart Beat Rate Determination in Digital Video Recordings of Rat Embryos

ADVANCES IN MASS DATA ANALYSIS OF IMAGES AND SIGNALS IN MEDICINE, BIOTECHNOLOGY, CHEMISTRY AND FOOD INDUSTRY, PRCEEDINGS, 2008, p.27-37

2008

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Teratogenicity of the I(Kr)-blocker cisapride: relation to embryonic cardiac arrhythmia

Reproductive toxicology (Elmsford, N.Y.), 2002-07, Vol.16 (4), p.333

2002

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Phenytoin teratogenicity: Hypoxia marker and effects on embryonic heart rhythm suggest an hERG-related mechanism: Hypoxia and Phenytoin Teratogenicity

Birth defects research. A Clinical and molecular teratology, 2005-03, Vol.73 (3), p.146-153

2005

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Stage-specific skeletal and visceral defects of the IKr-blocker almokalant: Further evidence for teratogenicity via a hypoxia-related mechanism

Teratology (Philadelphia), 2001-12, Vol.64 (6), p.292-300

2001

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Placental transfer and fetal distribution of lead in mice after treatment with dithiocarbamates

Archives of toxicology, 1984-03, Vol.55 (1), p.27-33

1984

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Drugs during pregnancy : an issue of risk classification and information to prescribers

Drug safety, 1996-02, Vol.14 (2), p.69-77

1996

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Embryonic cardiac arrhythmia and generation of reactive oxygen species: Common teratogenic mechanism for IKr blocking drugs

Is erythromycin therapy teratogenic in humans?

Effects of the antiepileptic drugs lamotrigine, topiramate and gabapentin on hERG potassium currents

Fetal safety of erythromycin. An update of Swedish data

Embryonic Arrhythmia by Inhibition of HERG Channels: A Common Hypoxia‐related Teratogenic Mechanism for Antiepileptic Drugs?

Maternal toxicity

Teratogenicity by the hERG potassium channel blocking drug almokalant: use of hypoxia marker gives evidence for a hypoxia-related mechanism mediated via embryonic arrhythmia

Increased Susceptibility to Phenytoin Teratogenicity: Excessive Generation of Reactive Oxygen Species or Impaired Antioxidant Defense?

Phenytoin teratogenicity: Hypoxia marker and effects on embryonic heart rhythm suggest an hERG-related mechanism

ILSI/HESI maternal toxicity workshop summary: maternal toxicity and its impact on study design and data interpretation

Phenytoin and phenobarbital inhibit human HERG potassium channels

New proposals for testing drugs with IKr-blocking activity to determine their teratogenic potential

Polytherapy with hERG-blocking antiepileptic drugs: Increased risk for embryonic cardiac arrhythmia and teratogenicity

Teratogenicity of the IKr-blocker cisapride: relation to embryonic cardiac arrhythmia

Teratogenicity of the class III antiarrhythmic drug almokalant. Role of hypoxia and reactive oxygen species

Exaggerated pharmacology versus true toxicity—Part 1

Phenytoin-induced cleft palate: Evidence for embryonic cardiac bradyarrhythmia due to inhibition of delayed rectifier k+ channels resulting in hypoxia-reoxygenation damage

Improved methodology for identifying the teratogenic potential in early drug development of hERG channel blocking drugs

Polytherapy with hERG-blocking antiepileptic drugs: Increased risk for embryonic cardiac arrhythmia and teratogenicity

Fully Automatic Heart Beat Rate Determination in Digital Video Recordings of Rat Embryos

Teratogenicity of the I(Kr)-blocker cisapride: relation to embryonic cardiac arrhythmia

Phenytoin teratogenicity: Hypoxia marker and effects on embryonic heart rhythm suggest an hERG-related mechanism: Hypoxia and Phenytoin Teratogenicity

Stage-specific skeletal and visceral defects of the IKr-blocker almokalant: Further evidence for teratogenicity via a hypoxia-related mechanism

Placental transfer and fetal distribution of lead in mice after treatment with dithiocarbamates

Drugs during pregnancy : an issue of risk classification and information to prescribers

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