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Identification of a Helical Segment within the Intrinsically Disordered Region of the PCSK9 Prodomain

Journal of molecular biology, 2019-03, Vol.431 (5), p.885-903

2019

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Structure, function, and activation of coagulation factor VII

Current protein & peptide science, 2002-06, Vol.3 (3), p.287-299

Eigenbrot, Charles

2002

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Structure of the Epidermal Growth Factor Receptor Kinase Domain Alone and in Complex with a 4-Anilinoquinazoline Inhibitor

The Journal of biological chemistry, 2002-11, Vol.277 (48), p.46265-46272

2002

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The Factor VII Zymogen Structure Reveals Reregistration of β Strands during Activation

Structure (London), 2001-07, Vol.9 (7), p.627-636

2001

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Discovery of Peptidomimetic Antibody–Drug Conjugate Linkers with Enhanced Protease Specificity

Journal of medicinal chemistry, 2018-02, Vol.61 (3), p.989-1000

2018

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Endocytosis and sorting of ErbB2 and the site of action of cancer therapeutics trastuzumab and geldanamycin

Molecular biology of the cell, 2004-12, Vol.15 (12), p.5268-5282

2004

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An Open-and-Shut Case? Recent Insights into the Activation of EGF/ErbB Receptors

Molecular Cell, 2003-09, Vol.12 (3), p.541-552

2003

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Rapid identification of reactive cysteine residues for site-specific labeling of antibody-Fabs

Journal of immunological methods, 2008-03, Vol.332 (1), p.41-52

2008

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A Novel Exosite on Coagulation Factor VIIa and Its Molecular Interactions with a New Class of Peptide Inhibitors

Biochemistry (Easton), 2001-08, Vol.40 (32), p.9522-9531

2001

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The Tissue Factor Region That Interacts with Factor Xa in the Activation of Factor VII

Biochemistry (Easton), 2001-01, Vol.40 (3), p.675-682

2001

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X-ray structure of glial cell-derived neurotrophic factor at 1.9 Å resolution and implications for receptor binding

Nature structural biology, 1997-06, Vol.4 (6), p.435-438

1997

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Aspartate Isomerization in the Complementarity-Determining Regions of Two Closely Related Monoclonal Antibodies

Biochemistry (Easton), 2007-02, Vol.46 (6), p.1534-1544

2007

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High-affinity Human Antibodies from Phage-displayed Synthetic Fab Libraries with a Single Framework Scaffold

Journal of molecular biology, 2004-07, Vol.340 (5), p.1073-1093

2004

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Function Blocking Antibodies to Neuropilin-1 Generated from a Designed Human Synthetic Antibody Phage Library

Journal of molecular biology, 2007-02, Vol.366 (3), p.815-829

2007

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Phage-displayed Antibody Libraries of Synthetic Heavy Chain Complementarity Determining Regions

Journal of molecular biology, 2004-04, Vol.338 (2), p.299-310

2004

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Crystal Structure at 1.7 angstrom resolution of VEGF in complex with domain 2 of the Flt-1 receptor

Cell, 1997-11, Vol.91 (5), p.695-704

1997

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Tissue Expression, Protease Specificity, and Kunitz Domain Functions of Hepatocyte Growth Factor Activator Inhibitor-1B (HAI-1B), a New Splice Variant of HAI-1

The Journal of biological chemistry, 2003-09, Vol.278 (38), p.36341-36349

2003

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Structural and Functional Basis of the Serine Protease-like Hepatocyte Growth Factor β-Chain in Met Binding and Signaling

The Journal of biological chemistry, 2004-09, Vol.279 (38), p.39915-39924

2004

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Crystal and molecular structure of the silver(II) and zinc(II) derivatives of meso-tetraphenylporphyrin. An exploration of crystal-packing effects on bond distance

Inorganic chemistry, 1986-03, Vol.25 (6), p.795-799

1986

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Conformational Lability in Serine Protease Active Sites: Structures of Hepatocyte Growth Factor Activator (HGFA) Alone and with the Inhibitory Domain from HGFA Inhibitor-1B

Journal of molecular biology, 2005-03, Vol.346 (5), p.1335-1349

2005

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X-ray crystal structure of the protease inhibitor domain of Alzheimer's amyloid .beta.-protein precursor

Biochemistry (Easton), 1990-10, Vol.29 (43), p.10018-10022

1990

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A deoxymyoglobin model with a sterically unhindered axial imidazole

Journal of the American Chemical Society, 1988-02, Vol.110 (4), p.1207-1215

1988

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Engineering Exosite Peptides for Complete Inhibition of Factor VIIa Using a Protease Switch with Substrate Phage

The Journal of biological chemistry, 2003-06, Vol.278 (24), p.21823-21830

2003

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A Selective, Slow Binding Inhibitor of Factor VIIa Binds to a Nonstandard Active Site Conformation and Attenuates Thrombus Formation in Vivo

The Journal of biological chemistry, 2005-03, Vol.280 (10), p.9160-9169

2005

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New Insight into How Tissue Factor Allosterically Regulates Factor VIIa

Trends in Cardiovascular Medicine, 2002, Vol.12 (1), p.19-26

2002

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Identification of a Helical Segment within the Intrinsically Disordered Region of the PCSK9 Prodomain

Structure, function, and activation of coagulation factor VII

Structure of the Epidermal Growth Factor Receptor Kinase Domain Alone and in Complex with a 4-Anilinoquinazoline Inhibitor

The Factor VII Zymogen Structure Reveals Reregistration of β Strands during Activation

Discovery of Peptidomimetic Antibody–Drug Conjugate Linkers with Enhanced Protease Specificity

Endocytosis and sorting of ErbB2 and the site of action of cancer therapeutics trastuzumab and geldanamycin

An Open-and-Shut Case? Recent Insights into the Activation of EGF/ErbB Receptors

Rapid identification of reactive cysteine residues for site-specific labeling of antibody-Fabs

A Novel Exosite on Coagulation Factor VIIa and Its Molecular Interactions with a New Class of Peptide Inhibitors

The Tissue Factor Region That Interacts with Factor Xa in the Activation of Factor VII

X-ray structure of glial cell-derived neurotrophic factor at 1.9 Å resolution and implications for receptor binding

Aspartate Isomerization in the Complementarity-Determining Regions of Two Closely Related Monoclonal Antibodies

High-affinity Human Antibodies from Phage-displayed Synthetic Fab Libraries with a Single Framework Scaffold

Function Blocking Antibodies to Neuropilin-1 Generated from a Designed Human Synthetic Antibody Phage Library

Phage-displayed Antibody Libraries of Synthetic Heavy Chain Complementarity Determining Regions

Crystal Structure at 1.7 angstrom resolution of VEGF in complex with domain 2 of the Flt-1 receptor

Tissue Expression, Protease Specificity, and Kunitz Domain Functions of Hepatocyte Growth Factor Activator Inhibitor-1B (HAI-1B), a New Splice Variant of HAI-1

Structural and Functional Basis of the Serine Protease-like Hepatocyte Growth Factor β-Chain in Met Binding and Signaling

Crystal and molecular structure of the silver(II) and zinc(II) derivatives of meso-tetraphenylporphyrin. An exploration of crystal-packing effects on bond distance

Conformational Lability in Serine Protease Active Sites: Structures of Hepatocyte Growth Factor Activator (HGFA) Alone and with the Inhibitory Domain from HGFA Inhibitor-1B

X-ray crystal structure of the protease inhibitor domain of Alzheimer's amyloid .beta.-protein precursor

A deoxymyoglobin model with a sterically unhindered axial imidazole

Engineering Exosite Peptides for Complete Inhibition of Factor VIIa Using a Protease Switch with Substrate Phage

A Selective, Slow Binding Inhibitor of Factor VIIa Binds to a Nonstandard Active Site Conformation and Attenuates Thrombus Formation in Vivo

New Insight into How Tissue Factor Allosterically Regulates Factor VIIa

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