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Structural Investigations of Full-Length Insulin Receptor Dynamics and Signalling

Journal of molecular biology, 2022-03, Vol.434 (5), p.167458-167458, Article 167458

2022

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Suppression of Insulin Receptor Substrate 1 Inhibits Breast Cancer Growth In Vitro and in Female Athymic Mice

Endocrinology (Philadelphia), 2023-03, Vol.164 (3), p.1

2023

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Insulin Receptor Isoforms in Physiology and Disease: An Updated View

Endocrine reviews, 2017-10, Vol.38 (5), p.379-431

2017

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The Activation Mechanism of the Insulin Receptor: A Structural Perspective

Annual review of biochemistry, 2023-06, Vol.92, p.247

2023

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Cell cycle control by the insulin-like growth factor signal: at the crossroad between cell growth and mitotic regulation

Cell cycle (Georgetown, Tex.), 2023-01, Vol.22 (1), p.1-37

2023

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Insulin Receptor Isoforms and Insulin Receptor/Insulin-Like Growth Factor Receptor Hybrids in Physiology and Disease

Endocrine reviews, 2009-10, Vol.30 (6), p.586-623

2009

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Regulation of insulin sensitivity by serine/threonine phosphorylation of insulin receptor substrate proteins IRS1 and IRS2

Diabetologia, 2012-10, Vol.55 (10), p.2565-2582

2012

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Insulin receptor in the brain: Mechanisms of activation and the role in the CNS pathology and treatment

CNS neuroscience & therapeutics, 2018-09, Vol.24 (9), p.763-774

2018

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Understanding insulin and its receptor from their three-dimensional structures

Molecular metabolism (Germany), 2021-10, Vol.52, p.101255-101255, Article 101255

Lawrence, Michael C.

2021

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Demonstrated brain insulin resistance in Alzheimer's disease patients is associated with IGF-1 resistance, IRS-1 dysregulation, and cognitive decline

The Journal of clinical investigation, 2012-04, Vol.122 (4), p.1316-1338

2012

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Defects in IGF-1 receptor, insulin receptor and IRS-1/2 in Alzheimer's disease indicate possible resistance to IGF-1 and insulin signalling

Neurobiology of aging, 2010-02, Vol.31 (2), p.224-243

2010

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Involvement of Insulin Signaling Disturbances in Bisphenol A-Induced Alzheimer's Disease-like Neurotoxicity

Scientific reports, 2017-08, Vol.7 (1), p.7497-12, Article 7497

2017

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BRD7 improves glucose homeostasis independent of IRS proteins

Journal of endocrinology, 2023-09, Vol.258 (3)

2023

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Regulation of insulin and type 1 insulin‐like growth factor signaling and action by the Grb10/14 and SH2B1/B2 adaptor proteins

The FEBS journal, 2013-02, Vol.280 (3), p.794-816

2013

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The P300 acetyltransferase inhibitor C646 promotes membrane translocation of insulin receptor protein substrate and interaction with the insulin receptor

The Journal of biological chemistry, 2022-03, Vol.298 (3), p.101621-101621, Article 101621

2022

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Imbalanced Insulin Actions in Obesity and Type 2 Diabetes: Key Mouse Models of Insulin Signaling Pathway

Cell metabolism, 2017-04, Vol.25 (4), p.797-810

2017

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Phosphorylation of IRS proteins, insulin action, and insulin resistance

American journal of physiology: endocrinology and metabolism, 2009-04, Vol.296 (4), p.E581-E591

2009

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Minimal Tags for Rapid Dual-Color Live-Cell Labeling and Super-Resolution Microscopy

Angewandte Chemie (International ed.), 2014-02, Vol.53 (8), p.2245-2249

International ed. in English, 2014

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New insights into the signaling system and function of insulin in fish

General and comparative endocrinology, 2011-09, Vol.173 (2), p.227-247

2011

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miR-27b Modulates Insulin Signaling in Hepatocytes by Regulating Insulin Receptor Expression

International journal of molecular sciences, 2020-11, Vol.21 (22), p.8675

2020

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Induction of miR-96 by Dietary Saturated Fatty Acids Exacerbates Hepatic Insulin Resistance through the Suppression of INSR and IRS-1

PloS one, 2016-12, Vol.11 (12), p.e0169039-e0169039

2016

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Liver adapts mitochondrial function to insulin resistant and diabetic states in mice

Journal of hepatology, 2014-04, Vol.60 (4), p.816-823

2014

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Insulin action at a molecular level – 100 years of progress

Molecular metabolism (Germany), 2021-10, Vol.52, p.101304-101304, Article 101304

2021

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Leucine-973 is a crucial residue differentiating insulin and IGF-1 receptor signaling

The Journal of clinical investigation, 2023-02, Vol.133 (4)

2023

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Structural Investigations of Full-Length Insulin Receptor Dynamics and Signalling

Suppression of Insulin Receptor Substrate 1 Inhibits Breast Cancer Growth In Vitro and in Female Athymic Mice

Insulin Receptor Isoforms in Physiology and Disease: An Updated View

The Activation Mechanism of the Insulin Receptor: A Structural Perspective

Cell cycle control by the insulin-like growth factor signal: at the crossroad between cell growth and mitotic regulation

Insulin Receptor Isoforms and Insulin Receptor/Insulin-Like Growth Factor Receptor Hybrids in Physiology and Disease

Regulation of insulin sensitivity by serine/threonine phosphorylation of insulin receptor substrate proteins IRS1 and IRS2

Insulin receptor in the brain: Mechanisms of activation and the role in the CNS pathology and treatment

Understanding insulin and its receptor from their three-dimensional structures

Demonstrated brain insulin resistance in Alzheimer's disease patients is associated with IGF-1 resistance, IRS-1 dysregulation, and cognitive decline

Defects in IGF-1 receptor, insulin receptor and IRS-1/2 in Alzheimer's disease indicate possible resistance to IGF-1 and insulin signalling

Involvement of Insulin Signaling Disturbances in Bisphenol A-Induced Alzheimer's Disease-like Neurotoxicity

BRD7 improves glucose homeostasis independent of IRS proteins

Regulation of insulin and type 1 insulin‐like growth factor signaling and action by the Grb10/14 and SH2B1/B2 adaptor proteins

The P300 acetyltransferase inhibitor C646 promotes membrane translocation of insulin receptor protein substrate and interaction with the insulin receptor

Imbalanced Insulin Actions in Obesity and Type 2 Diabetes: Key Mouse Models of Insulin Signaling Pathway

Phosphorylation of IRS proteins, insulin action, and insulin resistance

Minimal Tags for Rapid Dual-Color Live-Cell Labeling and Super-Resolution Microscopy

Astrocytic Insulin Signaling Couples Brain Glucose Uptake with Nutrient Availability

New insights into the signaling system and function of insulin in fish

miR-27b Modulates Insulin Signaling in Hepatocytes by Regulating Insulin Receptor Expression

Induction of miR-96 by Dietary Saturated Fatty Acids Exacerbates Hepatic Insulin Resistance through the Suppression of INSR and IRS-1

Liver adapts mitochondrial function to insulin resistant and diabetic states in mice

Insulin action at a molecular level – 100 years of progress

Leucine-973 is a crucial residue differentiating insulin and IGF-1 receptor signaling

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