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Identification of Dihydrofuro[3,4‑d]pyrimidine Derivatives as Novel HIV‑1 Non-Nucleoside Reverse Transcriptase Inhibitors with Promising Antiviral Activities and Desirable Physicochemical Properties

Journal of medicinal chemistry, 2019-02, Vol.62 (3), p.1484-1501

2019

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Enhanced anti-amnestic effect of donepezil by Ginkgo biloba extract (EGb 761) via further improvement in pro-cholinergic and antioxidative activities

Journal of ethnopharmacology, 2021-04, Vol.269, p.113711, Article 113711

2021

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Development of Novel Dihydrofuro[3,4‑d]pyrimidine Derivatives as HIV‑1 NNRTIs to Overcome the Highly Resistant Mutant Strains F227L/V106A and K103N/Y181C

Journal of medicinal chemistry, 2022-02, Vol.65 (3), p.2458-2470

2022

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Discovery of a Novel, Orally Active Himbacine-Based Thrombin Receptor Antagonist (SCH 530348) with Potent Antiplatelet Activity

Journal of medicinal chemistry, 2008-06, Vol.51 (11), p.3061-3064

2008

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A-803467, a potent and selective Nav1.8 sodium channel blocker, attenuates neuropathic and inflammatory pain in the rat

Proceedings of the National Academy of Sciences - PNAS, 2007-05, Vol.104 (20), p.8520-8525

2007

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Quantification of plasma remdesivir and its metabolite GS-441524 using liquid chromatography coupled to tandem mass spectrometry. Application to a Covid-19 treated patient

Clinical chemistry and laboratory medicine, 2020-08, Vol.58 (9), p.1461

2020

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Apparent Half-Lives of Dioxins, Furans, and Polychlorinated Biphenyls as a Function of Age, Body Fat, Smoking Status, and Breast-Feeding

Environmental health perspectives, 2009-03, Vol.117 (3), p.417-425

2009

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Isolation, Chemical, and Biotransformation Routes of Labdane-type Diterpenes

Chemical reviews, 2011-08, Vol.111 (8), p.4418-4452

2011

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An integrated strategy for revealing the pharmacological changes based on metabolites profiling and network pharmacology: Arctiin as an example

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2020-11, Vol.1157, p.122270, Article 122270

2020

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Fosamprenavir with Ritonavir Pharmacokinetics during Pregnancy

Antimicrobial agents and chemotherapy, 2020-03, Vol.64 (4)

2020

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Phase 1 dose-finding and pharmacokinetic study of eribulin-liposomal formulation in patients with solid tumours

British journal of cancer, 2019-02, Vol.120 (4), p.379-386

2019

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FFPM, a PDE4 inhibitor, reverses learning and memory deficits in APP/PS1 transgenic mice via cAMP/PKA/CREB signaling and anti-inflammatory effects

Neuropharmacology, 2017-04, Vol.116, p.260-269

2017

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Design, synthesis and biological evaluation of fused naphthofuro[3,2-c] quinoline-6,7,12-triones and pyrano[3,2-c]quinoline-6,7,8,13-tetraones derivatives as ERK inhibitors with efficacy in BRAF-mutant melanoma

Bioorganic chemistry, 2019-02, Vol.82, p.290-305

2019

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4-Aminoindazolyl-dihydrofuro[3,4-d]pyrimidines as non-covalent inhibitors of mutant epidermal growth factor receptor tyrosine kinase

Bioorganic & medicinal chemistry letters, 2016-01, Vol.26 (2), p.534-539

2016

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A case report on potential postmortem redistribution of furanyl fentanyl and 4-ANPP

Forensic science international, 2019-11, Vol.304, p.109915-109915, Article 109915

2019

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Eribulin Induces Irreversible Mitotic Blockade: Implications of Cell-Based Pharmacodynamics for In vivo Efficacy under Intermittent Dosing Conditions

Cancer research (Chicago, Ill.), 2011-01, Vol.71 (2), p.496-505

2011

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Sustained Accumulation of Microtubule-Binding Chemotherapy Drugs in the Peripheral Nervous System: Correlations with Time Course and Neurotoxic Severity

Cancer research (Chicago, Ill.), 2016-06, Vol.76 (11), p.3332-3339

2016

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Optimization of G-CSF dosing schedule in patients treated with eribulin: a modeling approach

Cancer chemotherapy and pharmacology, 2022-02, Vol.89 (2), p.197-208

2022

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Bioaccessibility of polychlorinated dioxins and furans in soil from a Superfund site

Chemosphere (Oxford), 2019-01, Vol.214, p.418-423

2019

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Identification of a PDE4-Specific Pocket for the Design of Selective Inhibitors

Biochemistry (Easton), 2018-07, Vol.57 (30), p.4518-4525

2018

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Phosphoinositide 3-Kinase (PI3K) Reactive Oxygen Species (ROS)-Activated Prodrug in Combination with Anthracycline Impairs PI3K Signaling, Increases DNA Damage Response and Reduces Breast Cancer Cell Growth

International journal of molecular sciences, 2021-02, Vol.22 (4), p.2088

2021

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Eribulin Mesylate

Clinical cancer research, 2011-11, Vol.17 (21), p.6615-6622

2011

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Effects of the sigma-1 receptor agonist blarcamesine in a murine model of fragile X syndrome: neurobehavioral phenotypes and receptor occupancy

Scientific reports, 2021-08, Vol.11 (1), p.17150-14, Article 17150

2021

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Effect of Soy Sauce on Serum Uric Acid Levels in Hyperuricemic Rats and Identification of Flazin as a Potent Xanthine Oxidase Inhibitor

Journal of agricultural and food chemistry, 2016-06, Vol.64 (23), p.4725-4734

2016

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A phase 1b/2, open-label, dose-escalation, and dose-confirmation study of eribulin mesilate in combination with capecitabine

British journal of cancer, 2019-03, Vol.120 (6), p.579-586

2019

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Identification of Dihydrofuro[3,4‑d]pyrimidine Derivatives as Novel HIV‑1 Non-Nucleoside Reverse Transcriptase Inhibitors with Promising Antiviral Activities and Desirable Physicochemical Properties

Enhanced anti-amnestic effect of donepezil by Ginkgo biloba extract (EGb 761) via further improvement in pro-cholinergic and antioxidative activities

Development of Novel Dihydrofuro[3,4‑d]pyrimidine Derivatives as HIV‑1 NNRTIs to Overcome the Highly Resistant Mutant Strains F227L/V106A and K103N/Y181C

Discovery of a Novel, Orally Active Himbacine-Based Thrombin Receptor Antagonist (SCH 530348) with Potent Antiplatelet Activity

A-803467, a potent and selective Nav1.8 sodium channel blocker, attenuates neuropathic and inflammatory pain in the rat

Quantification of plasma remdesivir and its metabolite GS-441524 using liquid chromatography coupled to tandem mass spectrometry. Application to a Covid-19 treated patient

Apparent Half-Lives of Dioxins, Furans, and Polychlorinated Biphenyls as a Function of Age, Body Fat, Smoking Status, and Breast-Feeding

Isolation, Chemical, and Biotransformation Routes of Labdane-type Diterpenes

An integrated strategy for revealing the pharmacological changes based on metabolites profiling and network pharmacology: Arctiin as an example

Fosamprenavir with Ritonavir Pharmacokinetics during Pregnancy

Phase 1 dose-finding and pharmacokinetic study of eribulin-liposomal formulation in patients with solid tumours

FFPM, a PDE4 inhibitor, reverses learning and memory deficits in APP/PS1 transgenic mice via cAMP/PKA/CREB signaling and anti-inflammatory effects

Design, synthesis and biological evaluation of fused naphthofuro[3,2-c] quinoline-6,7,12-triones and pyrano[3,2-c]quinoline-6,7,8,13-tetraones derivatives as ERK inhibitors with efficacy in BRAF-mutant melanoma

4-Aminoindazolyl-dihydrofuro[3,4-d]pyrimidines as non-covalent inhibitors of mutant epidermal growth factor receptor tyrosine kinase

A case report on potential postmortem redistribution of furanyl fentanyl and 4-ANPP

Eribulin Induces Irreversible Mitotic Blockade: Implications of Cell-Based Pharmacodynamics for In vivo Efficacy under Intermittent Dosing Conditions

Sustained Accumulation of Microtubule-Binding Chemotherapy Drugs in the Peripheral Nervous System: Correlations with Time Course and Neurotoxic Severity

Optimization of G-CSF dosing schedule in patients treated with eribulin: a modeling approach

Bioaccessibility of polychlorinated dioxins and furans in soil from a Superfund site

Identification of a PDE4-Specific Pocket for the Design of Selective Inhibitors

Phosphoinositide 3-Kinase (PI3K) Reactive Oxygen Species (ROS)-Activated Prodrug in Combination with Anthracycline Impairs PI3K Signaling, Increases DNA Damage Response and Reduces Breast Cancer Cell Growth

Eribulin Mesylate

Effects of the sigma-1 receptor agonist blarcamesine in a murine model of fragile X syndrome: neurobehavioral phenotypes and receptor occupancy

Effect of Soy Sauce on Serum Uric Acid Levels in Hyperuricemic Rats and Identification of Flazin as a Potent Xanthine Oxidase Inhibitor

A phase 1b/2, open-label, dose-escalation, and dose-confirmation study of eribulin mesilate in combination with capecitabine

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