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Intranasal drug delivery of didanosine-loaded chitosan nanoparticles for brain targeting; an attractive route against infections caused by aids viruses

Journal of drug targeting, 2010-06, Vol.18 (5), p.381-388

2010

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Anti-HIV efficacy and biodistribution of nucleoside reverse transcriptase inhibitors delivered as squalenoylated prodrug nanoassemblies

Biomaterials, 2013-07, Vol.34 (20), p.4831-4838

2013

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Bifunctional Peptidomimetic Prodrugs of Didanosine for Improved Intestinal Permeability and Enhanced Acidic Stability: Synthesis, Transepithelial Transport, Chemical Stability and Pharmacokinetics

Molecular pharmaceutics, 2011-04, Vol.8 (2), p.319-329

2011

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Mannosylated gelatin nanoparticles bearing an anti-HIV drug didanosine for site-specific delivery

Nanomedicine, 2008-03, Vol.4 (1), p.41-48

2008

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Efavirenz Capsule Sprinkle and Liquid Formulations With Didanosine and Emtricitabine in HIV-1-infected Infants and Children 3 Months to 6 Years of Age: Study AI266-922

The Pediatric infectious disease journal, 2015-12, Vol.34 (12), p.1355-1360

2015

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Combination Anti-HIV Therapy with the Self-Assemblies of an Asymmetric Bolaamphiphilic Zidovudine/Didanosine Prodrug

Molecular pharmaceutics, 2011-06, Vol.8 (3), p.867-876

2011

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Mannan-coated gelatin nanoparticles for sustained and targeted delivery of didanosine: In vitro and in vivo evaluation

Acta pharmaceutica (Zagreb, Croatia), 2008-03, Vol.58 (1), p.61-74

2008

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Simultaneous determination of 2′,3′-dideoxyinosine and the active metabolite, 2′,3′-dideoxyadenosine-5′-triphosphate in human peripheral-blood mononuclear cell by HPLC–MS/MS and the application to cell pharmacokinetics

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2015-10, Vol.1002, p.337-342

2015

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In vivo absorption of didanosine formulated in pellets composed of chitosan microspheres

In vivo (Athens), 2014-11, Vol.28 (6), p.1045-1050

2014

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Novel oleic acid derivatives enhance buccal permeation of didanosine

Drug development and industrial pharmacy, 2014-05, Vol.40 (5), p.657-668

2014

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Measurement of Intracellular Didanosine and Tenofovir Phosphorylated Metabolites and Possible Interaction of the Two Drugs in Human Immunodeficiency Virus-Infected Patients

Antimicrobial Agents and Chemotherapy, 2005-05, Vol.49 (5), p.1907-1914

2005

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Self-assembled drug delivery systems: Part 3. In vitro/in vivo studies of the self-assembled nanoparticulates of cholesteryl acyl didanosine

International journal of pharmaceutics, 2009-02, Vol.368 (1-2), p.207-214

2009

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Submicron-size biodegradable polymer-based didanosine particles for treating HIV at early stage: an in vitro study

Journal of microencapsulation, 2012-11, Vol.29 (7), p.666-676

2012

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A new nanomedicine based on didanosine glycerolipidic prodrug enhances the long term accumulation of drug in a HIV sanctuary

International journal of pharmaceutics, 2011-07, Vol.414 (1), p.285-297

2011

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A novel pharmacokinetic approach to predict virologic failure in HIV-1-infected paediatric patients

AIDS (London), 2013-03, Vol.27 (5), p.761-768

2013

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Role of Purine Nucleoside Phosphorylase in Interactions between 2′,3′-Dideoxyinosine and Allopurinol, Ganciclovir, or Tenofovir

Antimicrobial Agents and Chemotherapy, 2004-04, Vol.48 (4), p.1089-1095

2004

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Comparative buccal permeability enhancement of didanosine and tenofovir by potential multifunctional polymeric excipients and their effects on porcine buccal histology

Pharmaceutical development and technology, 2014-02, Vol.19 (1), p.82-90

2014

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Intracellular Nucleotide Levels during Coadministration of Tenofovir Disoproxil Fumarate and Didanosine in HIV-1-Infected Patients

Antimicrobial Agents and Chemotherapy, 2011-04, Vol.55 (4), p.1549-1555

2011

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Simultaneous determination of didanosine and its amino acid prodrug, valdidanosine by hydrophilic interaction chromatography coupled with electrospray ionization tandem mass spectrometry: Application to a pharmacokinetic study in rats

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2010-02, Vol.878 (3), p.466-470

2010

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Drug-Drug and Drug-Food Interactions Between Tenofovir Disoproxil Fumarate and Didanosine

Journal of clinical pharmacology, 2005-12, Vol.45 (12), p.1360-1367

2005

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Strategies to improve efficacy and safety of a novel class of antiviral hyper‐activation‐limiting therapeutic agents: the VS411 model HIV/AIDS

British journal of pharmacology, 2010-10, Vol.161 (4), p.830-843

2010

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Investigating the effect of Aloe vera gel on the buccal permeability of didanosine

Planta medica, 2012-03, Vol.78 (4), p.354-361

2012

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Is the Recommended Once-Daily Dose of Lamivudine Optimal in West African HIV-Infected Children?

Antimicrobial Agents and Chemotherapy, 2010-08, Vol.54 (8), p.3280-3286

2010

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Didanosine Population Pharmacokinetics in West African Human Immunodeficiency Virus-Infected Children Administered Once-Daily Tablets in Relation to Efficacy after One Year of Treatment

Antimicrobial Agents and Chemotherapy, 2009-10, Vol.53 (10), p.4399-4406

2009

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Didanosine extended-release matrix tablets: optimization of formulation variables using statistical experimental design

International journal of pharmaceutics, 2002-04, Vol.237 (1), p.107-118

2002

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Intranasal drug delivery of didanosine-loaded chitosan nanoparticles for brain targeting; an attractive route against infections caused by aids viruses

Anti-HIV efficacy and biodistribution of nucleoside reverse transcriptase inhibitors delivered as squalenoylated prodrug nanoassemblies

Bifunctional Peptidomimetic Prodrugs of Didanosine for Improved Intestinal Permeability and Enhanced Acidic Stability: Synthesis, Transepithelial Transport, Chemical Stability and Pharmacokinetics

Mannosylated gelatin nanoparticles bearing an anti-HIV drug didanosine for site-specific delivery

Efavirenz Capsule Sprinkle and Liquid Formulations With Didanosine and Emtricitabine in HIV-1-infected Infants and Children 3 Months to 6 Years of Age: Study AI266-922

Combination Anti-HIV Therapy with the Self-Assemblies of an Asymmetric Bolaamphiphilic Zidovudine/Didanosine Prodrug

Mannan-coated gelatin nanoparticles for sustained and targeted delivery of didanosine: In vitro and in vivo evaluation

Simultaneous determination of 2′,3′-dideoxyinosine and the active metabolite, 2′,3′-dideoxyadenosine-5′-triphosphate in human peripheral-blood mononuclear cell by HPLC–MS/MS and the application to cell pharmacokinetics

In vivo absorption of didanosine formulated in pellets composed of chitosan microspheres

Novel oleic acid derivatives enhance buccal permeation of didanosine

Measurement of Intracellular Didanosine and Tenofovir Phosphorylated Metabolites and Possible Interaction of the Two Drugs in Human Immunodeficiency Virus-Infected Patients

Self-assembled drug delivery systems: Part 3. In vitro/in vivo studies of the self-assembled nanoparticulates of cholesteryl acyl didanosine

Submicron-size biodegradable polymer-based didanosine particles for treating HIV at early stage: an in vitro study

A new nanomedicine based on didanosine glycerolipidic prodrug enhances the long term accumulation of drug in a HIV sanctuary

A novel pharmacokinetic approach to predict virologic failure in HIV-1-infected paediatric patients

Role of Purine Nucleoside Phosphorylase in Interactions between 2′,3′-Dideoxyinosine and Allopurinol, Ganciclovir, or Tenofovir

Comparative buccal permeability enhancement of didanosine and tenofovir by potential multifunctional polymeric excipients and their effects on porcine buccal histology

Intracellular Nucleotide Levels during Coadministration of Tenofovir Disoproxil Fumarate and Didanosine in HIV-1-Infected Patients

Simultaneous determination of didanosine and its amino acid prodrug, valdidanosine by hydrophilic interaction chromatography coupled with electrospray ionization tandem mass spectrometry: Application to a pharmacokinetic study in rats

Drug-Drug and Drug-Food Interactions Between Tenofovir Disoproxil Fumarate and Didanosine

Strategies to improve efficacy and safety of a novel class of antiviral hyper‐activation‐limiting therapeutic agents: the VS411 model HIV/AIDS

Investigating the effect of Aloe vera gel on the buccal permeability of didanosine

Is the Recommended Once-Daily Dose of Lamivudine Optimal in West African HIV-Infected Children?

Didanosine Population Pharmacokinetics in West African Human Immunodeficiency Virus-Infected Children Administered Once-Daily Tablets in Relation to Efficacy after One Year of Treatment

Didanosine extended-release matrix tablets: optimization of formulation variables using statistical experimental design

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