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COMMD1 is linked to the WASH complex and regulates endosomal trafficking of the copper transporter ATP7A

Molecular biology of the cell, 2015-01, Vol.26 (1), p.91-103

2015

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Human copper transporter 2 is localized in late endosomes and lysosomes and facilitates cellular copper uptake

Biochemical journal, 2007-10, Vol.407 (1), p.49-59

2007

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COMMD Family Regulates Plasma LDL Levels and Attenuates Atherosclerosis Through Stabilizing the CCC Complex in Endosomal LDLR Trafficking

Circulation research, 2018-06, Vol.122 (12), p.1648-1660

2018

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A novel role for XIAP in copper homeostasis through regulation of MURR1

The EMBO journal, 2004-01, Vol.23 (1), p.244-254

2004

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Function of the endolysosomal network in cholesterol homeostasis and metabolic-associated fatty liver disease (MAFLD)

Molecular metabolism (Germany), 2021-08, Vol.50, p.101146-101146, Article 101146

2021

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Haploid genetic screens identify SPRING/C12ORF49 as a determinant of SREBP signaling and cholesterol metabolism

Nature communications, 2020-02, Vol.11 (1), p.1128-1128, Article 1128

2020

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Mechanism of leukemogenesis by the inv(16) chimeric gene CBFB/PEBP2B-MHY11

Oncogene, 2004-05, Vol.23 (24), p.4297-4307

2004

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Mice with a deficiency in Peroxisomal Membrane Protein 4 (PXMP4) display mild changes in hepatic lipid metabolism

Scientific reports, 2022-02, Vol.12 (1), p.2512-2512, Article 2512

2022

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A human-like bile acid pool induced by deletion of hepatic Cyp2c70 modulates effects of FXR activation in mice[S]

Journal of lipid research, 2020-03, Vol.61 (3), p.291-305

2020

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Prevention of Triglyceridemia by (Non-)Anticoagulant Heparin(oids) Does Not Preclude Transplant Vasculopathy and Glomerulosclerosis

Frontiers in cell and developmental biology, 2022-03, Vol.10, p.798088-798088

2022

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The S/T-Rich Motif in the DNAJB6 Chaperone Delays Polyglutamine Aggregation and the Onset of Disease in a Mouse Model

Molecular cell, 2016-04, Vol.62 (2), p.272-283

2016

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The NADPH oxidase Nox4 has anti-atherosclerotic functions

European heart journal, 2015-12, Vol.36 (48), p.3447-3456

2015

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Increased expression of BubR1 protects against aneuploidy and cancer and extends healthy lifespan

Nature cell biology, 2013-01, Vol.15 (1), p.96-102

2013

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CCC- and WASH-mediated endosomal sorting of LDLR is required for normal clearance of circulating LDL

Nature communications, 2016-03, Vol.7 (1), p.10961-10961, Article 10961

2016

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T cell cholesterol efflux suppresses apoptosis and senescence and increases atherosclerosis in middle aged mice

Nature communications, 2022-07, Vol.13 (1), p.3799-3799, Article 3799

2022

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Novel aspects of PCSK9 and lipoprotein receptors in renal disease-related dyslipidemia

Cellular signalling, 2019-03, Vol.55, p.53-64

2019

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Selective Hepatic Cbs Knockout Aggravates Liver Damage, Endothelial Dysfunction and ROS Stress in Mice Fed a Western Diet

International journal of molecular sciences, 2023-04, Vol.24 (8), p.7019

2023

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Hypercholesterolemia in Progressive Renal Failure Is Associated with Changes in Hepatic Heparan Sulfate - PCSK9 Interaction

Journal of the American Society of Nephrology, 2021-06, Vol.32 (6), p.1371-1388

2021

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Impaired Hepatic Vitamin A Metabolism in NAFLD Mice Leading to Vitamin A Accumulation in Hepatocytes

Cellular and molecular gastroenterology and hepatology, 2021-01, Vol.11 (1), p.309-325.e3

2021

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A20 deficiency in myeloid cells protects mice from diet-induced obesity and insulin resistance due to increased fatty acid metabolism

Cell reports (Cambridge), 2021-09, Vol.36 (12), p.109748-109748, Article 109748

2021

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Accumulation of 5-oxoproline in myocardial dysfunction and the protective effects of OPLAH

Science translational medicine, 2017-11, Vol.9 (415)

2017

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Regulation of murine copper homeostasis by members of the COMMD protein family

Disease models & mechanisms, 2021-01, Vol.14 (1)

2021

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The hepatocyte IKK:NF-κB axis promotes liver steatosis by stimulating de novo lipogenesis and cholesterol synthesis

Molecular metabolism (Germany), 2021-12, Vol.54, p.101349-101349, Article 101349

2021

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COMMD1 disrupts HIF-1α/β dimerization and inhibits human tumor cell invasion

The Journal of clinical investigation, 2010-06, Vol.120 (6), p.2119-2130

2010

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Reduced life- and healthspan in mice carrying a mono-allelic BubR1 MVA mutation

PLoS genetics, 2012-12, Vol.8 (12), p.e1003138

2012

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COMMD1 is linked to the WASH complex and regulates endosomal trafficking of the copper transporter ATP7A

Human copper transporter 2 is localized in late endosomes and lysosomes and facilitates cellular copper uptake

COMMD Family Regulates Plasma LDL Levels and Attenuates Atherosclerosis Through Stabilizing the CCC Complex in Endosomal LDLR Trafficking

A novel role for XIAP in copper homeostasis through regulation of MURR1

Function of the endolysosomal network in cholesterol homeostasis and metabolic-associated fatty liver disease (MAFLD)

Haploid genetic screens identify SPRING/C12ORF49 as a determinant of SREBP signaling and cholesterol metabolism

Mechanism of leukemogenesis by the inv(16) chimeric gene CBFB/PEBP2B-MHY11

Mice with a deficiency in Peroxisomal Membrane Protein 4 (PXMP4) display mild changes in hepatic lipid metabolism

A human-like bile acid pool induced by deletion of hepatic Cyp2c70 modulates effects of FXR activation in mice[S]

Prevention of Triglyceridemia by (Non-)Anticoagulant Heparin(oids) Does Not Preclude Transplant Vasculopathy and Glomerulosclerosis

The S/T-Rich Motif in the DNAJB6 Chaperone Delays Polyglutamine Aggregation and the Onset of Disease in a Mouse Model

The NADPH oxidase Nox4 has anti-atherosclerotic functions

Increased expression of BubR1 protects against aneuploidy and cancer and extends healthy lifespan

CCC- and WASH-mediated endosomal sorting of LDLR is required for normal clearance of circulating LDL

T cell cholesterol efflux suppresses apoptosis and senescence and increases atherosclerosis in middle aged mice

Novel aspects of PCSK9 and lipoprotein receptors in renal disease-related dyslipidemia

Selective Hepatic Cbs Knockout Aggravates Liver Damage, Endothelial Dysfunction and ROS Stress in Mice Fed a Western Diet

Hypercholesterolemia in Progressive Renal Failure Is Associated with Changes in Hepatic Heparan Sulfate - PCSK9 Interaction

Impaired Hepatic Vitamin A Metabolism in NAFLD Mice Leading to Vitamin A Accumulation in Hepatocytes

A20 deficiency in myeloid cells protects mice from diet-induced obesity and insulin resistance due to increased fatty acid metabolism

Accumulation of 5-oxoproline in myocardial dysfunction and the protective effects of OPLAH

Regulation of murine copper homeostasis by members of the COMMD protein family

The hepatocyte IKK:NF-κB axis promotes liver steatosis by stimulating de novo lipogenesis and cholesterol synthesis

COMMD1 disrupts HIF-1α/β dimerization and inhibits human tumor cell invasion

Reduced life- and healthspan in mice carrying a mono-allelic BubR1 MVA mutation

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