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In Utero Undernutrition in Male Mice Programs Liver Lipid Metabolism in the Second-Generation Offspring Involving Altered Lxra DNA Methylation

Cell metabolism, 2014-06, Vol.19 (6), p.941-951

2014

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A human-like bile acid pool induced by deletion of hepatic Cyp2c70 modulates effects of FXR activation in mice[S]

Journal of lipid research, 2020-03, Vol.61 (3), p.291-305

2020

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Transintestinal Cholesterol Transport Is Active in Mice and Humans and Controls Ezetimibe-Induced Fecal Neutral Sterol Excretion

Cell metabolism, 2016-12, Vol.24 (6), p.783-794

2016

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Statins increase hepatic cholesterol synthesis and stimulate fecal cholesterol elimination in mice

Journal of lipid research, 2016-08, Vol.57 (8), p.1455-1464

2016

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Malnutrition-associated liver steatosis and ATP depletion is caused by peroxisomal and mitochondrial dysfunction

Journal of hepatology, 2016-12, Vol.65 (6), p.1198-1208

2016

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Hepatic Carbohydrate Response Element Binding Protein Activation Limits Nonalcoholic Fatty Liver Disease Development in a Mouse Model for Glycogen Storage Disease Type 1a

Hepatology (Baltimore, Md.), 2020-11, Vol.72 (5), p.1638-1653

2020

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Genetic and Microbial Associations to Plasma and Fecal Bile Acids in Obesity Relate to Plasma Lipids and Liver Fat Content

Cell reports (Cambridge), 2020-10, Vol.33 (1), p.108212-108212, Article 108212

2020

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Hepatic farnesoid X-receptor isoforms α2 and α4 differentially modulate bile salt and lipoprotein metabolism in mice

PloS one, 2014-12, Vol.9 (12), p.e115028-e115028

2014

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Identification of Side Chain Oxidized Sterols as Novel Liver X Receptor Agonists with Therapeutic Potential in the Treatment of Cardiovascular and Neurodegenerative Diseases

International journal of molecular sciences, 2023-01, Vol.24 (2), p.1290

2023

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FXR overexpression alters adipose tissue architecture in mice and limits its storage capacity leading to metabolic derangements[S]

Journal of lipid research, 2019-09, Vol.60 (9), p.1547-1561

2019

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An epigenome-wide association study identifies multiple DNA methylation markers of exposure to endocrine disruptors

Environment international, 2020-11, Vol.144, p.106016, Article 106016

2020

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Beyond intestinal soap--bile acids in metabolic control

Nature reviews. Endocrinology, 2014-08, Vol.10 (8), p.488

2014

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The hepatocyte IKK:NF-κB axis promotes liver steatosis by stimulating de novo lipogenesis and cholesterol synthesis

Molecular metabolism (Germany), 2021-12, Vol.54, p.101349-101349, Article 101349

2021

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Potential of therapeutic bile acids in the treatment of neonatal Hyperbilirubinemia

Scientific reports, 2021-05, Vol.11 (1), p.11107-10, Article 11107

2021

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Low production of 12α-hydroxylated bile acids prevents hepatic steatosis in Cyp2c70−/− mice by reducing fat absorption

Journal of lipid research, 2021-01, Vol.62, p.100134-100134, Article 100134

2021

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Spontaneous liver disease in wild-type C57BL/6JOlaHsd mice fed semisynthetic diet

PloS one, 2020-09, Vol.15 (9), p.e0232069-e0232069

2020

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Mice with a deficiency in Peroxisomal Membrane Protein 4 (PXMP4) display mild changes in hepatic lipid metabolism

Scientific reports, 2022-02, Vol.12 (1), p.2512-2512, Article 2512

2022

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Pharmacological inhibition of MEK1/2 signaling disrupts bile acid metabolism through loss of Shp and enhanced Cyp7a1 expression

Biomedicine & pharmacotherapy, 2023-03, Vol.159, p.114270, Article 114270

2023

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Intestinal PPARδ protects against diet-induced obesity, insulin resistance and dyslipidemia

Scientific reports, 2017-04, Vol.7 (1), p.846-846, Article 846

2017

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The liver X-receptor gene promoter is hypermethylated in a mouse model of prenatal protein restriction

American journal of physiology. Regulatory, integrative and comparative physiology, 2010-02, Vol.298 (2), p.R275-R282

2010

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24(S)-Hydroxycholesterol Participates in a Liver X Receptor-controlled Pathway in Astrocytes That Regulates Apolipoprotein E-mediated Cholesterol Efflux

The Journal of biological chemistry, 2006-05, Vol.281 (18), p.12799-12808

2006

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Stimulation of Lipogenesis by Pharmacological Activation of the Liver X Receptor Leads to Production of Large, Triglyceride-rich Very Low Density Lipoprotein Particles

The Journal of biological chemistry, 2002-09, Vol.277 (37), p.34182-34190

2002

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Cholangiopathy and Biliary Fibrosis in Cyp2c70-Deficient Mice Are Fully Reversed by Ursodeoxycholic Acid

Cellular and molecular gastroenterology and hepatology, 2021-01, Vol.11 (4), p.1045-1069

2021

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Response to Spontaneous Cholemia in C57BL/6 Mice Predisposes to Liver Cancer in NASH

Cellular and molecular gastroenterology and hepatology, 2022-01, Vol.13 (5), p.1590-1590

2022

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In Utero Undernutrition in Male Mice Programs Liver Lipid Metabolism in the Second-Generation Offspring Involving Altered Lxra DNA Methylation

A human-like bile acid pool induced by deletion of hepatic Cyp2c70 modulates effects of FXR activation in mice[S]

Transintestinal Cholesterol Transport Is Active in Mice and Humans and Controls Ezetimibe-Induced Fecal Neutral Sterol Excretion

Statins increase hepatic cholesterol synthesis and stimulate fecal cholesterol elimination in mice

Malnutrition-associated liver steatosis and ATP depletion is caused by peroxisomal and mitochondrial dysfunction

Hepatic Carbohydrate Response Element Binding Protein Activation Limits Nonalcoholic Fatty Liver Disease Development in a Mouse Model for Glycogen Storage Disease Type 1a

Genetic and Microbial Associations to Plasma and Fecal Bile Acids in Obesity Relate to Plasma Lipids and Liver Fat Content

Hepatic farnesoid X-receptor isoforms α2 and α4 differentially modulate bile salt and lipoprotein metabolism in mice

Identification of Side Chain Oxidized Sterols as Novel Liver X Receptor Agonists with Therapeutic Potential in the Treatment of Cardiovascular and Neurodegenerative Diseases

FXR overexpression alters adipose tissue architecture in mice and limits its storage capacity leading to metabolic derangements[S]

An epigenome-wide association study identifies multiple DNA methylation markers of exposure to endocrine disruptors

Beyond intestinal soap--bile acids in metabolic control

The hepatocyte IKK:NF-κB axis promotes liver steatosis by stimulating de novo lipogenesis and cholesterol synthesis

Potential of therapeutic bile acids in the treatment of neonatal Hyperbilirubinemia

Low production of 12α-hydroxylated bile acids prevents hepatic steatosis in Cyp2c70−/− mice by reducing fat absorption

Spontaneous liver disease in wild-type C57BL/6JOlaHsd mice fed semisynthetic diet

Mice with a deficiency in Peroxisomal Membrane Protein 4 (PXMP4) display mild changes in hepatic lipid metabolism

Pharmacological inhibition of MEK1/2 signaling disrupts bile acid metabolism through loss of Shp and enhanced Cyp7a1 expression

Systematic analysis of relationships between plasma branched-chain amino acid concentrations and cardiometabolic parameters: an association and Mendelian randomization study

Intestinal PPARδ protects against diet-induced obesity, insulin resistance and dyslipidemia

The liver X-receptor gene promoter is hypermethylated in a mouse model of prenatal protein restriction

24(S)-Hydroxycholesterol Participates in a Liver X Receptor-controlled Pathway in Astrocytes That Regulates Apolipoprotein E-mediated Cholesterol Efflux

Stimulation of Lipogenesis by Pharmacological Activation of the Liver X Receptor Leads to Production of Large, Triglyceride-rich Very Low Density Lipoprotein Particles

Cholangiopathy and Biliary Fibrosis in Cyp2c70-Deficient Mice Are Fully Reversed by Ursodeoxycholic Acid

Response to Spontaneous Cholemia in C57BL/6 Mice Predisposes to Liver Cancer in NASH

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