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Molecular determinants of bacterial sensitivity and resistance to mammalian Group IIA phospholipase A2

Biochimica et biophysica acta, 2015-11, Vol.1848 (11), p.3072-3077

Weiss, Jerrold P.

2015

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High-mobility group nucleosome-binding protein 1 acts as an alarmin and is critical for lipopolysaccharide-induced immune responses

The Journal of experimental medicine, 2012-01, Vol.209 (1), p.157-171

2012

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The bactericidal/permeability-increasing protein (BPI) in infection and inflammatory disease

Clinica chimica acta, 2007-09, Vol.384 (1-2), p.12-23

2007

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LBP/BPI proteins and their relatives: conservation over evolution and roles in mutualism

Biochemical Society transactions, 2011-08, Vol.39 (4), p.1039-1044

2011

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Isolation of an Endotoxin-MD-2 Complex That Produces Toll-Like Receptor 4-Dependent Cell Activation at Picomolar Concentrations

Proceedings of the National Academy of Sciences - PNAS, 2004-03, Vol.101 (12), p.4186-4191

2004

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Essential Roles of Hydrophobic Residues in Both MD-2 and Toll-like Receptor 4 in Activation by Endotoxin

The Journal of biological chemistry, 2009-05, Vol.284 (22), p.15052-15060

2009

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Neutrophil Bleaching of GFP-Expressing Staphylococci: Probing the Intraphagosomal Fate of Individual Bacteria

The Journal of immunology (1950), 2009-08, Vol.183 (4), p.2632-2641

2009

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Evidence Suggesting That Francisella tularensis O-Antigen Capsule Contains a Lipid A-Like Molecule That Is Structurally Distinct from the More Abundant Free Lipid A

PloS one, 2016-06, Vol.11 (6), p.e0157842-e0157842

2016

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Expression of Functional D299G.T399I Polymorphic Variant of TLR4 Depends More on Coexpression of MD-2 Than Does Wild-Type TLR4

The Journal of immunology (1950), 2010-04, Vol.184 (8), p.4362-4367

2010

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Wall Teichoic Acid Deficiency in Staphylococcus aureus Confers Selective Resistance to Mammalian Group IIA Phospholipase A₂ and Human β-Defensin 3

Infection and Immunity, 2008-05, Vol.76 (5), p.2169-2176

2008

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Biochemical transformation of bacterial lipopolysaccharides by acyloxyacyl hydrolase reduces host injury and promotes recovery

The Journal of biological chemistry, 2020-12, Vol.295 (51), p.17842-17851

2020

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Respiratory syncytial virus fusion protein-induced toll-like receptor 4 (TLR4) signaling is inhibited by the TLR4 antagonists Rhodobacter sphaeroides lipopolysaccharide and eritoran (E5564) and requires direct interaction with MD-2

mBio, 2012, Vol.3 (4)

2012

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Tetraacylated lipid A and paclitaxel-selective activation of TLR4/MD-2 conferred through hydrophobic interactions

The Journal of immunology (1950), 2014-02, Vol.192 (4), p.1887-1895

2014

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17(R)-Resolvin D1 differentially regulates TLR4-mediated responses of primary human macrophages to purified LPS and live E. coli

Journal of leukocyte biology, 2011-09, Vol.90 (3), p.459-470

2011

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Cation-Induced Transcriptional Regulation of the dlt Operon of Staphylococcus aureus

Journal of Bacteriology, 2006-05, Vol.188 (10), p.3622-3630

2006

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Endotoxin·albumin complexes transfer endotoxin monomers to MD-2 resulting in activation of TLR4

Innate immunity (London, England), 2012-06, Vol.18 (3), p.478-491

2012

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Detecting lipopolysaccharide in the cytosol of mammalian cells: Lessons from MD‐2/TLR4

Journal of leukocyte biology, 2019-07, Vol.106 (1), p.127-132

2019

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Biochemical and Functional Characterization of Membrane Blebs Purified from Neisseria meningitidis Serogroup B

The Journal of biological chemistry, 2005-11, Vol.280 (46), p.38383-38394

2005

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Cutting Edge: Mitochondrial Assembly of the NLRP3 Inflammasome Complex Is Initiated at Priming

The Journal of immunology (1950), 2018-05, Vol.200 (9), p.3047-3052

2018

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Novel Roles in Human MD-2 of Phenylalanines 121 and 126 and Tyrosine 131 in Activation of Toll-like Receptor 4 by Endotoxin

The Journal of biological chemistry, 2008-01, Vol.283 (3), p.1257-1266

2008

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Structural and functional features of a developmentally regulated lipopolysaccharide-binding protein

mBio, 2015-10, Vol.6 (5), p.e01193-e01115

2015

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Novel Roles of Lysines 122, 125, and 58 in Functional Differences between Human and Murine MD-2

The Journal of immunology (1950), 2009-10, Vol.183 (8), p.5138-5145

2009

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An Essential Role for Albumin in the Interaction of Endotoxin with Lipopolysaccharide-binding Protein and sCD14 and Resultant Cell Activation

The Journal of biological chemistry, 2002-12, Vol.277 (49), p.47818-47825

2002

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Endotoxin-binding Proteins Modulate the Susceptibility of Bacterial Endotoxin to Deacylation by Acyloxyacyl Hydrolase

The Journal of biological chemistry, 2007-03, Vol.282 (11), p.7877-7884

2007

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Regulation of interactions of Gram-negative bacterial endotoxins with mammalian cells

Immunologic research, 2007-11, Vol.39 (1-3), p.249-260

2007

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Molecular determinants of bacterial sensitivity and resistance to mammalian Group IIA phospholipase A2

High-mobility group nucleosome-binding protein 1 acts as an alarmin and is critical for lipopolysaccharide-induced immune responses

The bactericidal/permeability-increasing protein (BPI) in infection and inflammatory disease

LBP/BPI proteins and their relatives: conservation over evolution and roles in mutualism

Isolation of an Endotoxin-MD-2 Complex That Produces Toll-Like Receptor 4-Dependent Cell Activation at Picomolar Concentrations

Essential Roles of Hydrophobic Residues in Both MD-2 and Toll-like Receptor 4 in Activation by Endotoxin

Neutrophil Bleaching of GFP-Expressing Staphylococci: Probing the Intraphagosomal Fate of Individual Bacteria

Evidence Suggesting That Francisella tularensis O-Antigen Capsule Contains a Lipid A-Like Molecule That Is Structurally Distinct from the More Abundant Free Lipid A

Expression of Functional D299G.T399I Polymorphic Variant of TLR4 Depends More on Coexpression of MD-2 Than Does Wild-Type TLR4

Wall Teichoic Acid Deficiency in Staphylococcus aureus Confers Selective Resistance to Mammalian Group IIA Phospholipase A₂ and Human β-Defensin 3

Biochemical transformation of bacterial lipopolysaccharides by acyloxyacyl hydrolase reduces host injury and promotes recovery

Respiratory syncytial virus fusion protein-induced toll-like receptor 4 (TLR4) signaling is inhibited by the TLR4 antagonists Rhodobacter sphaeroides lipopolysaccharide and eritoran (E5564) and requires direct interaction with MD-2

Tetraacylated lipid A and paclitaxel-selective activation of TLR4/MD-2 conferred through hydrophobic interactions

17(R)-Resolvin D1 differentially regulates TLR4-mediated responses of primary human macrophages to purified LPS and live E. coli

Cation-Induced Transcriptional Regulation of the dlt Operon of Staphylococcus aureus

Endotoxin·albumin complexes transfer endotoxin monomers to MD-2 resulting in activation of TLR4

Detecting lipopolysaccharide in the cytosol of mammalian cells: Lessons from MD‐2/TLR4

Biochemical and Functional Characterization of Membrane Blebs Purified from Neisseria meningitidis Serogroup B

Cutting Edge: Mitochondrial Assembly of the NLRP3 Inflammasome Complex Is Initiated at Priming

Novel Roles in Human MD-2 of Phenylalanines 121 and 126 and Tyrosine 131 in Activation of Toll-like Receptor 4 by Endotoxin

Structural and functional features of a developmentally regulated lipopolysaccharide-binding protein

Novel Roles of Lysines 122, 125, and 58 in Functional Differences between Human and Murine MD-2

An Essential Role for Albumin in the Interaction of Endotoxin with Lipopolysaccharide-binding Protein and sCD14 and Resultant Cell Activation

Endotoxin-binding Proteins Modulate the Susceptibility of Bacterial Endotoxin to Deacylation by Acyloxyacyl Hydrolase

Regulation of interactions of Gram-negative bacterial endotoxins with mammalian cells

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