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Xanthone Derivatives and Their Potential Usage in the Treatment of Telangiectasia and Rosacea

Applied sciences, 2024-05, Vol.14 (10), p.4037

2024

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Antimutagenic compounds and their possible mechanisms of action

Journal of applied genetics, 2014-05, Vol.55 (2), p.273-285

2014

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Influence of protonation on the geometry of 2‐{[(2,6‐dimethylphenoxy)ethyl]amino}‐1‐phenylethan‐1‐ol: crystal structures of the free base and of its chloride and 3‐hydroxybenzoate salt forms

Acta crystallographica. Section C, Crystal structure communications, 2022-01, Vol.78 (1), p.14-22

2022

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KM-416, a novel phenoxyalkylaminoalkanol derivative with anticonvulsant properties exerts analgesic, local anesthetic, and antidepressant-like activities. Pharmacodynamic, pharmacokinetic, and forced degradation studies

European journal of pharmacology, 2020-11, Vol.886, p.173540, Article 173540

2020

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Four N-(E)-cinnamoyl (cinnamamide) derivatives of aminoalkanols with promising anticonvulsant and analgesic activity

Bioorganic & medicinal chemistry letters, 2019-06, Vol.29 (11), p.1298-1303

2019

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The conformational analyses of 2‐amino‐N‐[2‐(dimethylphenoxy)ethyl]propan‐1‐ol derivatives in different environments

Acta crystallographica. Section C, Crystal structure communications, 2020-07, Vol.76 (7), p.681-689

2020

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Synthesis and in vitro Evaluation of the Anticancer Potential of New Aminoalkanol Derivatives of Xanthone

Anti-cancer agents in medicinal chemistry, 2016-01, Vol.16 (12), p.1587-1604

2016

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Design, synthesis and evaluation of activity and pharmacokinetic profile of new derivatives of xanthone and piperazine in the central nervous system

Bioorganic & medicinal chemistry letters, 2019-11, Vol.29 (21), p.126679, Article 126679

2019

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Cinnamamide Derivatives for Central and Peripheral Nervous System Disorders-A Review of Structure-Activity Relationships

ChemMedChem, 2015-08, Vol.10 (8), p.1302-1325

2015

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Antidepressant- and Anxiolytic-Like Effects of New Dual 5-HT₁A and 5-HT₇ Antagonists in Animal Models

PloS one, 2015-11, Vol.10 (11), p.e0142499-e0142499

2015

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Beneficial effects of non-quinazoline α1-adrenolytics on hypertension and altered metabolism in fructose-fed rats. A comparison with prazosin

Nutrition, metabolism, and cardiovascular diseases, 2019-07, Vol.29 (7), p.751-760

2019

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Promising anticonvulsant and/or analgesic compounds among 5‐chloro‐2‐ or 5‐chloro‐4‐methyl derivatives of xanthone coupled to aminoalkanol moieties—Design, synthesis and pharmacological evaluation

Chemical biology & drug design, 2023-02, Vol.101 (2), p.278-325

2023

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Supramolecular architectures of succinates of 1‐hydroxypropan‐2‐aminium derivatives

Acta crystallographica. Section C, Crystal structure communications, 2018-07, Vol.74 (7), p.856-862

2018

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Structure-anticonvulsant activity studies in the group of (E)-N-cinnamoyl aminoalkanols derivatives monosubstituted in phenyl ring with 4-Cl, 4-CH3 or 2-CH3

Bioorganic & medicinal chemistry, 2017-01, Vol.25 (2), p.471-482

2017

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Sirtuins as a potential molecular target of cosmetic ingredients

Farmacja Polska, 2022-03, Vol.78 (1), p.19-28

2022

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Synthesis and Evaluation of Antidepressant-like Activity of Some 4-Substituted 1-(2-methoxyphenyl)Piperazine Derivatives

Chemical biology & drug design, 2015-03, Vol.85 (3), p.326-335

2015

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Design, synthesis and activity against Staphylococcus epidermidis of 5‐chloro‐2‐ or 5‐chloro‐4‐methyl‐9H‐xanthen‐9‐one and some of its derivatives

Chemical biology & drug design, 2021-03, Vol.97 (3), p.674-685

2021

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Contribution of reactive oxygen species to the anticancer activity of aminoalkanol derivatives of xanthone

Investigational new drugs, 2018-06, Vol.36 (3), p.355-369

2018

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N-[(2,6-Dimethylphenoxy)alkyl]aminoalkanols—their physicochemical and anticonvulsant properties

Bioorganic & medicinal chemistry, 2015-08, Vol.23 (15), p.4197-4217

2015

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Influence of the position of the methyl substituent and N‐oxide formation on the geometry and intermolecular interactions of 1‐(phenoxyethyl)piperidin‐4‐ol derivatives

Acta crystallographica. Section C, Crystal structure communications, 2020-01, Vol.76 (1), p.30-36

2020

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Synthesis and activity of di- or trisubstituted N-(phenoxyalkyl)- or N-{2-[2-(phenoxy)ethoxy]ethyl}piperazine derivatives on the central nervous system

Bioorganic & medicinal chemistry letters, 2018-06, Vol.28 (11), p.2039-2049

2018

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Design, synthesis, and anticonvulsant activity of some derivatives of xanthone with aminoalkanol moieties

Chemical biology & drug design, 2017-03, Vol.89 (3), p.339-352

2017

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Anti-Helicobacter pylori activities of selected N-substituted cinnamamide derivatives evaluated on reference and clinical bacterial strains

Journal of antibiotics, 2018-05, Vol.71 (5), p.543-548

2018

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HBK-14 and HBK-15 Do Not Influence Blood Pressure, Lipid Profile, Glucose Level, or Liver Enzymes Activity after Chronic Treatment in Rats

PloS one, 2016-10, Vol.11 (10), p.e0165495-e0165495

2016

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In vitro mutagenic, antimutagenic, and antioxidant activities evaluation and biotransformation of some bioactive 4-substituted 1-(2-methoxyphenyl)piperazine derivatives

Journal of biochemical and molecular toxicology, 2016-12, Vol.30 (12), p.593-601

2016

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Xanthone Derivatives and Their Potential Usage in the Treatment of Telangiectasia and Rosacea

Antimutagenic compounds and their possible mechanisms of action

Influence of protonation on the geometry of 2‐{[(2,6‐dimethylphenoxy)ethyl]amino}‐1‐phenylethan‐1‐ol: crystal structures of the free base and of its chloride and 3‐hydroxybenzoate salt forms

KM-416, a novel phenoxyalkylaminoalkanol derivative with anticonvulsant properties exerts analgesic, local anesthetic, and antidepressant-like activities. Pharmacodynamic, pharmacokinetic, and forced degradation studies

Four N-(E)-cinnamoyl (cinnamamide) derivatives of aminoalkanols with promising anticonvulsant and analgesic activity

The conformational analyses of 2‐amino‐N‐[2‐(dimethylphenoxy)ethyl]propan‐1‐ol derivatives in different environments

Synthesis and in vitro Evaluation of the Anticancer Potential of New Aminoalkanol Derivatives of Xanthone

Design, synthesis and evaluation of activity and pharmacokinetic profile of new derivatives of xanthone and piperazine in the central nervous system

Cinnamamide Derivatives for Central and Peripheral Nervous System Disorders-A Review of Structure-Activity Relationships

Antidepressant- and Anxiolytic-Like Effects of New Dual 5-HT₁A and 5-HT₇ Antagonists in Animal Models

Beneficial effects of non-quinazoline α1-adrenolytics on hypertension and altered metabolism in fructose-fed rats. A comparison with prazosin

Promising anticonvulsant and/or analgesic compounds among 5‐chloro‐2‐ or 5‐chloro‐4‐methyl derivatives of xanthone coupled to aminoalkanol moieties—Design, synthesis and pharmacological evaluation

Supramolecular architectures of succinates of 1‐hydroxypropan‐2‐aminium derivatives

Structure-anticonvulsant activity studies in the group of (E)-N-cinnamoyl aminoalkanols derivatives monosubstituted in phenyl ring with 4-Cl, 4-CH3 or 2-CH3

Sirtuins as a potential molecular target of cosmetic ingredients

Synthesis and Evaluation of Antidepressant-like Activity of Some 4-Substituted 1-(2-methoxyphenyl)Piperazine Derivatives

Design, synthesis and activity against Staphylococcus epidermidis of 5‐chloro‐2‐ or 5‐chloro‐4‐methyl‐9H‐xanthen‐9‐one and some of its derivatives

Contribution of reactive oxygen species to the anticancer activity of aminoalkanol derivatives of xanthone

N-[(2,6-Dimethylphenoxy)alkyl]aminoalkanols—their physicochemical and anticonvulsant properties

Influence of the position of the methyl substituent and N‐oxide formation on the geometry and intermolecular interactions of 1‐(phenoxyethyl)piperidin‐4‐ol derivatives

Synthesis and activity of di- or trisubstituted N-(phenoxyalkyl)- or N-{2-[2-(phenoxy)ethoxy]ethyl}piperazine derivatives on the central nervous system

Design, synthesis, and anticonvulsant activity of some derivatives of xanthone with aminoalkanol moieties

Anti-Helicobacter pylori activities of selected N-substituted cinnamamide derivatives evaluated on reference and clinical bacterial strains

HBK-14 and HBK-15 Do Not Influence Blood Pressure, Lipid Profile, Glucose Level, or Liver Enzymes Activity after Chronic Treatment in Rats

In vitro mutagenic, antimutagenic, and antioxidant activities evaluation and biotransformation of some bioactive 4-substituted 1-(2-methoxyphenyl)piperazine derivatives

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