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Bifunctional crosslinking ligands for transthyretin

Open biology, 2015-09, Vol.5 (9), p.150105-150105

2015

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3,4 -Dihydro -2H -benzoxazinones as dual-acting 5-HT1A receptor antagonists and serotonin reuptake inhibitors

Bioorganic & medicinal chemistry letters, 2007-02, Vol.17 (4), p.1033-1036

2007

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Studies on a series of potent, orally bioavailable, 5-HT1 receptor ligands

Bioorganic & medicinal chemistry letters, 2007-09, Vol.17 (18), p.5214-5217

2007

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Characterization of the binding of [3H]‐SB‐204269, a radiolabelled form of the new anticonvulsant SB‐204269, to a novel binding site in rat brain membranes

British journal of pharmacology, 1997-08, Vol.121 (8), p.1687-1691

1997

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Synthesis of Novel trans-4-(Substituted-benzamido)-3,4-dihydro-2H-benzo[b]pyran-3-ol Derivatives as Potential Anticonvulsant Agents with a Distinctive Binding Profile

Journal of medicinal chemistry, 1996-11, Vol.39 (23), p.4537-4539

1996

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3,4-Dihydro-2H-benzoxazinones are 5-HT1A receptor antagonists with potent 5-HT reuptake inhibitory activity

Bioorganic & medicinal chemistry letters, 2005-02, Vol.15 (3), p.737-741

2005

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Stereochemical differentiation of anticonvulsant and antihypertensive effects in 4-(fluorobenzoylamino)-benzopyrans

Bioorganic & medicinal chemistry letters, 1995-06, Vol.5 (11), p.1163-1166

1995

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Studies on a series of potent, orally bioavailable, 5-HT(1) receptor ligands

Bioorganic & medicinal chemistry letters, 2007-09, Vol.17 (18), p.5214-5217

2007

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Studies on a series of potent, orally bioavailable, 5-HT 1 receptor ligands

Bioorganic & medicinal chemistry letters, 2007, Vol.17 (18), p.5214-5217

2007

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Design and synthesis of novel 2,3-dihydro-1H-isoindoles with high affinity and selectivity for the dopamine D3 receptor

Bioorganic & medicinal chemistry letters, 2001-03, Vol.11 (5), p.685-688

2001

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Novel 2,3,4,5-tetrahydro-1H-3-benzazepines with high affinity and selectivity for the dopamine D3 receptor

Bioorganic & medicinal chemistry letters, 2000-11, Vol.10 (22), p.2553-2555

2000

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3,4-Dihydro-2H-benzoxazinones are 5-HT(1A) receptor antagonists with potent 5-HT reuptake inhibitory activity

Bioorganic & medicinal chemistry letters, 2005-02, Vol.15 (3), p.737-741

2005

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3,4-Dihydro-2@@iH@-benzoxazinones as dual-acting 5-HT@@d1A@ receptor antagonists and serotonin reuptake inhibitors

Bioorganic & medicinal chemistry letters, 2007-02, Vol.17 (4), p.1033-1036

2007

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Stereochemical preferences and requirement for the 3-hydroxyl group in novel anticonvulsant 4-fluorobenzoylamino benzopyrans

Bioorganic & medicinal chemistry letters, 1995-11, Vol.5 (21), p.2563-2566

1995

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Synthesis of Novel trans -4-(Substituted-benzamido)-3,4-dihydro-2 H -benzo[ b ]pyran-3-ol Derivatives as Potential Anticonvulsant Agents with a Distinctive Binding Profile

Journal of medicinal chemistry, 1996-01, Vol.39 (23), p.4537-4539

1996

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5.09 - Pyrans and their Benzo Derivatives: Applications

Comprehensive Heterocyclic Chemistry II, 1996, p.469-500

Second Edition, 1996

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Fast acting allosteric phosphofructokinase inhibitors block trypanosome glycolysis and cure acute African trypanosomiasis in mice

Nature communications, 2021-02, Vol.12 (1), p.1052-10, Article 1052

2021

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Tetrahydropyrido[3,4-b]pyrazine Scaffolds from Pentafluoropyridine

Journal of organic chemistry, 2005-09, Vol.70 (18), p.7208-7216

2005

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Synthesis of tetrahydropyrido[2,3- b]pyrazine scaffolds from 2,3,5,6-tetrafluoropyridine derivatives

Tetrahedron, 2007-06, Vol.63 (24), p.5204-5211

2007

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Pyrido[3,2-b][1,4]oxazine and pyrido[2,3-b][1,4]benzoxazine systems from tetrafluoropyridine derivatives

Journal of fluorine chemistry, 2014-11, Vol.167, p.91-95

2014

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Design and Synthesis of trans-3-(2-(4-((3-(3-(5-Methyl-1,2,4-oxadiazolyl))- phenyl)carboxamido)cyclohexyl)ethyl)-7-methylsulfonyl-2,3,4,5-tetrahydro- 1H-3-benzazepine (SB-414796): A Potent and Selective Dopamine D3 Receptor Antagonist

Bifunctional crosslinking ligands for transthyretin

3,4 -Dihydro -2H -benzoxazinones as dual-acting 5-HT1A receptor antagonists and serotonin reuptake inhibitors

Design and Synthesis of trans-N-[4-[2-(6-Cyano-1,2,3,4-tetrahydroisoquinolin-2- yl)ethyl]cyclohexyl]-4-quinolinecarboxamide (SB-277011): A Potent and Selective Dopamine D3 Receptor Antagonist with High Oral Bioavailability and CNS Penetration in the Rat

Studies on a series of potent, orally bioavailable, 5-HT1 receptor ligands

Characterization of the binding of [3H]‐SB‐204269, a radiolabelled form of the new anticonvulsant SB‐204269, to a novel binding site in rat brain membranes

Synthesis of Novel trans-4-(Substituted-benzamido)-3,4-dihydro-2H-benzo[b]pyran-3-ol Derivatives as Potential Anticonvulsant Agents with a Distinctive Binding Profile

3,4-Dihydro-2H-benzoxazinones are 5-HT1A receptor antagonists with potent 5-HT reuptake inhibitory activity

Design and Synthesis of trans - N -[4-[2-(6-Cyano-1,2,3,4-tetrahydroisoquinolin-2- yl)ethyl]cyclohexyl]-4-quinolinecarboxamide (SB-277011): A Potent and Selective Dopamine D 3 Receptor Antagonist with High Oral Bioavailability and CNS Penetration in the Rat

Stereochemical differentiation of anticonvulsant and antihypertensive effects in 4-(fluorobenzoylamino)-benzopyrans

Studies on a series of potent, orally bioavailable, 5-HT(1) receptor ligands

Studies on a series of potent, orally bioavailable, 5-HT 1 receptor ligands

Design and synthesis of novel 2,3-dihydro-1H-isoindoles with high affinity and selectivity for the dopamine D3 receptor

Novel 2,3,4,5-tetrahydro-1H-3-benzazepines with high affinity and selectivity for the dopamine D3 receptor

3,4-Dihydro-2H-benzoxazinones are 5-HT(1A) receptor antagonists with potent 5-HT reuptake inhibitory activity

Design and Synthesis of trans -3-(2-(4-((3-(3-(5-Methyl-1,2,4-oxadiazolyl))- phenyl)carboxamido)cyclohexyl)ethyl)-7-methylsulfonyl-2,3,4,5-tetrahydro- 1 H -3-benzazepine (SB-414796): A Potent and Selective Dopamine D 3 Receptor Antagonist

3,4-Dihydro-2@@iH@-benzoxazinones as dual-acting 5-HT@@d1A@ receptor antagonists and serotonin reuptake inhibitors

Design and synthesis of trans-3-2-4-3-(3-(5-methyl-1,2,4-oxadiazolyl))-phenylcarboxamidocyclohexyl ethyl-7-methylsulfonyl-2,3,4,5-tetrahydro-1H-3-benzazepine (SB-414796): A potent and selective dopamine D3 receptor antagonist

Stereochemical preferences and requirement for the 3-hydroxyl group in novel anticonvulsant 4-fluorobenzoylamino benzopyrans

Synthesis of Novel trans -4-(Substituted-benzamido)-3,4-dihydro-2 H -benzo[ b ]pyran-3-ol Derivatives as Potential Anticonvulsant Agents with a Distinctive Binding Profile

5.09 - Pyrans and their Benzo Derivatives: Applications

Fast acting allosteric phosphofructokinase inhibitors block trypanosome glycolysis and cure acute African trypanosomiasis in mice

Tetrahydropyrido[3,4-b]pyrazine Scaffolds from Pentafluoropyridine

Synthesis of tetrahydropyrido[2,3- b]pyrazine scaffolds from 2,3,5,6-tetrafluoropyridine derivatives

Pyrido[3,2-b][1,4]oxazine and pyrido[2,3-b][1,4]benzoxazine systems from tetrafluoropyridine derivatives

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