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Optimization of a Dibenzodiazepine Hit to a Potent and Selective Allosteric PAK1 Inhibitor

ACS medicinal chemistry letters, 2015-07, Vol.6 (7), p.776-781

2015

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Pangean (Late Carboniferous–Middle Jurassic) paleoenvironment and lithofacies

Palaeogeography, palaeoclimatology, palaeoecology, 2000-08, Vol.161 (1), p.1-34

2000

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Extended kinase profile and properties of the protein kinase inhibitor nilotinib

Biochimica et biophysica acta, 2010-03, Vol.1804 (3), p.445-453

2010

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7,8-Dichloro-1-oxo-β-carbolines as a Versatile Scaffold for the Development of Potent and Selective Kinase Inhibitors with Unusual Binding Modes

Journal of medicinal chemistry, 2012-01, Vol.55 (1), p.403-413

2012

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Tuffs, tectonism and glacially related sea-level changes, Carboniferous–Permian, southern Namibia

Palaeogeography, palaeoclimatology, palaeoecology, 2000-08, Vol.161 (1), p.127-150

2000

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Tetra-Substituted Pyridinylimidazoles As Dual Inhibitors of p38α Mitogen-Activated Protein Kinase and c‑Jun N‑Terminal Kinase 3 for Potential Treatment of Neurodegenerative Diseases

Journal of medicinal chemistry, 2015-01, Vol.58 (1), p.443-456

2015

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Late Palaeozoic evolution of the North Atlantic margin of Pangea

Palaeogeography, palaeoclimatology, palaeoecology, 2000-08, Vol.161 (1), p.95-126

Stemmerik, Lars

2000

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Promiscuity analysis of a kinase panel screen with designated p38 alpha inhibitors

European journal of medicinal chemistry, 2020-02, Vol.187, p.112004-112004, Article 112004

2020

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The stratigraphic and geochemical record of Playa Cycles: monitoring a Pangaean monsoon-like system (Triassic, Middle Keuper, S. Germany)

Palaeogeography, palaeoclimatology, palaeoecology, 2000-08, Vol.161 (1), p.205-227

2000

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Approaches to selective fibroblast growth factor receptor 4 inhibition through targeting the ATP-pocket middle-hinge region

MedChemComm, 2017-08, Vol.8 (8), p.1604-1613

2017

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Potent and selective inhibition of polycythemia by the quinoxaline JAK2 inhibitor NVP-BSK805

Molecular cancer therapeutics, 2010-07, Vol.9 (7), p.1945-1955

2010

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Hot spot activity and the break-up of Pangea

Palaeogeography, palaeoclimatology, palaeoecology, 2000-08, Vol.161 (1), p.49-69

2000

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Palaeozoic terranes of the Balkan Peninsula in the framework of Pangea assembly

Palaeogeography, palaeoclimatology, palaeoecology, 2000-08, Vol.161 (1), p.151-177

Yanev, Slavcho

2000

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Novel heterocyclic DPP-4 inhibitors for the treatment of type 2 diabetes

Bioorganic & medicinal chemistry letters, 2012-02, Vol.22 (3), p.1464-1468

2012

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Cyclicity of Triassic to Lower Jurassic continental red beds of the Argana Valley, Morocco: implications for palaeoclimate and basin evolution

Palaeogeography, palaeoclimatology, palaeoecology, 2000-08, Vol.161 (1), p.229-266

2000

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Identification and optimisation of a 4′,5-bisthiazole series of selective phosphatidylinositol-3 kinase alpha inhibitors

Bioorganic & medicinal chemistry letters, 2015-09, Vol.25 (17), p.3569-3574

2015

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Discovery of C-(1-aryl-cyclohexyl)-methylamines as selective, orally available inhibitors of dipeptidyl peptidase IV

Bioorganic & medicinal chemistry letters, 2014-02, Vol.24 (3), p.731-736

2014

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A Novel Class of Oral Direct Renin Inhibitors: Highly Potent 3,5-Disubstituted Piperidines Bearing a Tricyclic P 3 – P 1 Pharmacophore

Journal of medicinal chemistry, 2013-03, Vol.56 (6), p.2196-2206

2013

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The Substrate-Activity-Screening methodology applied to receptor tyrosine kinases: A proof-of-concept study

European journal of medicinal chemistry, 2012-11, Vol.57, p.1-9

2012

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Floristic migration in South America during the Carboniferous: phytogeographic and biostratigraphic implications

Palaeogeography, palaeoclimatology, palaeoecology, 2000-08, Vol.161 (1), p.71-94

2000

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Carbon isotope compositions of the Late Permian carbonate rocks in southern China: their variations between the Wujiaping and Changxing formations

Palaeogeography, palaeoclimatology, palaeoecology, 2000-08, Vol.161 (1), p.179-192

2000

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Kinase Inhibition by Deoxy Analogues of the Resorcylic Lactone L-783277

ACS medicinal chemistry letters, 2011-01, Vol.2 (1), p.22-27

2011

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Pan-PIM Kinase Inhibition Provides a Novel Therapy for Treating Hematologic Cancers

Optimization of a Dibenzodiazepine Hit to a Potent and Selective Allosteric PAK1 Inhibitor

Pangean (Late Carboniferous–Middle Jurassic) paleoenvironment and lithofacies

Characterization of the novel and specific PI3Kα inhibitor NVP-BYL719 and development of the patient stratification strategy for clinical trials

Extended kinase profile and properties of the protein kinase inhibitor nilotinib

Targeting Plasmodium PI(4)K to eliminate malaria

7,8-Dichloro-1-oxo-β-carbolines as a Versatile Scaffold for the Development of Potent and Selective Kinase Inhibitors with Unusual Binding Modes

Tuffs, tectonism and glacially related sea-level changes, Carboniferous–Permian, southern Namibia

Tetra-Substituted Pyridinylimidazoles As Dual Inhibitors of p38α Mitogen-Activated Protein Kinase and c‑Jun N‑Terminal Kinase 3 for Potential Treatment of Neurodegenerative Diseases

Late Palaeozoic evolution of the North Atlantic margin of Pangea

Promiscuity analysis of a kinase panel screen with designated p38 alpha inhibitors

The stratigraphic and geochemical record of Playa Cycles: monitoring a Pangaean monsoon-like system (Triassic, Middle Keuper, S. Germany)

Approaches to selective fibroblast growth factor receptor 4 inhibition through targeting the ATP-pocket middle-hinge region

Potent and selective inhibition of polycythemia by the quinoxaline JAK2 inhibitor NVP-BSK805

Hot spot activity and the break-up of Pangea

Palaeozoic terranes of the Balkan Peninsula in the framework of Pangea assembly

Novel heterocyclic DPP-4 inhibitors for the treatment of type 2 diabetes

Cyclicity of Triassic to Lower Jurassic continental red beds of the Argana Valley, Morocco: implications for palaeoclimate and basin evolution

Identification and optimisation of a 4′,5-bisthiazole series of selective phosphatidylinositol-3 kinase alpha inhibitors

Discovery of C-(1-aryl-cyclohexyl)-methylamines as selective, orally available inhibitors of dipeptidyl peptidase IV

A Novel Class of Oral Direct Renin Inhibitors: Highly Potent 3,5-Disubstituted Piperidines Bearing a Tricyclic P 3 – P 1 Pharmacophore

The Substrate-Activity-Screening methodology applied to receptor tyrosine kinases: A proof-of-concept study

Floristic migration in South America during the Carboniferous: phytogeographic and biostratigraphic implications

Carbon isotope compositions of the Late Permian carbonate rocks in southern China: their variations between the Wujiaping and Changxing formations

Kinase Inhibition by Deoxy Analogues of the Resorcylic Lactone L-783277

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