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How Phenotypic Screening Influenced Drug Discovery: Lessons from Five Years of Practice

Assay and drug development technologies, 2017-08, Vol.15 (6), p.239

2017

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A High-Throughput Screening Identifies MICU1 Targeting Compounds

Cell reports (Cambridge), 2020-02, Vol.30 (7), p.2321-2331.e6

2020

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Nuclear export of proteins in plants: AtXPO1 is the export receptor for leucine‐rich nuclear export signals in Arabidopsis thaliana

The Plant journal : for cell and molecular biology, 1999-12, Vol.20 (6), p.695-705

1999

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Arabidopsis transportin1 is the nuclear import receptor for the circadian clock-regulated RNA-binding protein AtGRP7

Plant molecular biology, 2003-09, Vol.53 (1-2), p.201-212

2003

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Different species of alpha-synuclein oligomers induce calcium influx and seeding

The Journal of neuroscience, 2007-08, Vol.27 (34), p.9220-9232

2007

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High content screening of CXCR2-dependent signalling pathways

Combinatorial chemistry & high throughput screening, 2010-01, Vol.13 (1), p.3

2010

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G Protein‐Coupled Receptor Internalization Assays in the High‐Content Screening Format

Measuring Biological Responses with Automated Microscopy, 2006, Vol.414, p.121-139

2006

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Comparison of G-protein coupled receptor desensitization-related beta-arrestin redistribution using confocal and non-confocal imaging

Combinatorial chemistry & high throughput screening, 2006-01, Vol.9 (1), p.37

2006

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A Drug Resistance Screen Using a Selective MET Inhibitor Reveals a Spectrum of Mutations That Partially Overlap with Activating Mutations Found in Cancer Patients

Cancer research (Chicago, Ill.), 2011-08, Vol.71 (15), p.5255-5264

2011

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Discovery of novel pyrrolidineoxy-substituted heteroaromatics as potent and selective PI3K delta inhibitors with improved physicochemical properties

Bioorganic & medicinal chemistry letters, 2016-12, Vol.26 (23), p.5657-5662

2016

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Identification and optimisation of a 4′,5-bisthiazole series of selective phosphatidylinositol-3 kinase alpha inhibitors

Bioorganic & medicinal chemistry letters, 2015-09, Vol.25 (17), p.3569-3574

2015

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Targeting Plasmodium phosphatidylinositol 4-kinase to eliminate malaria

Nature (London), 2013-11, Vol.504 (7479), p.248-253

2013

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Pharmacological Profiling of Chemokine Receptor–Directed Compounds Using High-Content Screening

Journal of biomolecular screening, 2008-01, Vol.13 (1), p.40-53

2008

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Abstract 4738: Cellular resistance screening with a novel selective c-Met inhibitor reveals a spectrum of missense mutations that partially overlap with activating mutations found in cancer patients

Cancer research (Chicago, Ill.), 2011-04, Vol.71 (8_Supplement), p.4738-4738

2011

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Automated high content screening for phosphoinositide 3 kinase inhibition using an AKT 1 redistribution assay

Combinatorial chemistry & high throughput screening, 2006-06, Vol.9 (5), p.339

2006

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Characterization of kinase inhibitors using reverse phase protein arrays

Methods in molecular biology (Clifton, N.J.), 2011, Vol.785, p.79

2011

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Different Species of {alpha}-Synuclein Oligomers Induce Calcium Influx and Seeding

The Journal of neuroscience, 2007-08, Vol.27 (34), p.9220

2007

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Seminar: Kinderschutz in internationalen Freiwilligendiensten

Voluntaris, 2018, Vol.6 (1), p.114-120

2018

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Chronische Depression: Verstehen ; Behandeln ; Erforschen

1. Aufl., 2013

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Psychotherapie in Ostdeutschland: Geschichte und Geschichten 1945-1995

Geyer, Michael

1. Aufl., 2011

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How Phenotypic Screening Influenced Drug Discovery: Lessons from Five Years of Practice

A High-Throughput Screening Identifies MICU1 Targeting Compounds

Nuclear export of proteins in plants: AtXPO1 is the export receptor for leucine‐rich nuclear export signals in Arabidopsis thaliana

Arabidopsis transportin1 is the nuclear import receptor for the circadian clock-regulated RNA-binding protein AtGRP7

Different species of alpha-synuclein oligomers induce calcium influx and seeding

High content screening of CXCR2-dependent signalling pathways

Targeting Plasmodium PI(4)K to eliminate malaria

G Protein‐Coupled Receptor Internalization Assays in the High‐Content Screening Format

Comparison of G-protein coupled receptor desensitization-related beta-arrestin redistribution using confocal and non-confocal imaging

A Drug Resistance Screen Using a Selective MET Inhibitor Reveals a Spectrum of Mutations That Partially Overlap with Activating Mutations Found in Cancer Patients

Discovery of novel pyrrolidineoxy-substituted heteroaromatics as potent and selective PI3K delta inhibitors with improved physicochemical properties

Identification and optimisation of a 4′,5-bisthiazole series of selective phosphatidylinositol-3 kinase alpha inhibitors

Targeting Plasmodium phosphatidylinositol 4-kinase to eliminate malaria

Pharmacological Profiling of Chemokine Receptor–Directed Compounds Using High-Content Screening

Abstract 4738: Cellular resistance screening with a novel selective c-Met inhibitor reveals a spectrum of missense mutations that partially overlap with activating mutations found in cancer patients

Automated high content screening for phosphoinositide 3 kinase inhibition using an AKT 1 redistribution assay

Characterization of kinase inhibitors using reverse phase protein arrays

Different Species of {alpha}-Synuclein Oligomers Induce Calcium Influx and Seeding

Seminar: Kinderschutz in internationalen Freiwilligendiensten

Chronische Depression: Verstehen ; Behandeln ; Erforschen

Psychotherapie in Ostdeutschland: Geschichte und Geschichten 1945-1995

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