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Sensing of HSV-1 by the cGAS-STING pathway in microglia orchestrates antiviral defence in the CNS

Nature communications, 2016-11, Vol.7 (1), p.13348-13348, Article 13348

2016

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Pre-Clinical Models to Study Human Prostate Cancer

Cancers, 2023-08, Vol.15 (17), p.4212

2023

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The cGAS-STING pathway is a therapeutic target in a preclinical model of hepatocellular carcinoma

Oncogene, 2020-02, Vol.39 (8), p.1652-1664

2020

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Lack of immunological DNA sensing in hepatocytes facilitates hepatitis B virus infection

Hepatology (Baltimore, Md.), 2016-09, Vol.64 (3), p.746-759

2016

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Application of CRISPR for In Vivo Mouse Cancer Studies

Cancers, 2022-10, Vol.14 (20), p.5014

Thomsen, Martin K.

2022

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Influenza A virus targets a cGAS-independent STING pathway that controls enveloped RNA viruses

Nature communications, 2016-02, Vol.7 (1), p.10680-10680, Article 10680

2016

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STING agonists enable antiviral cross-talk between human cells and confer protection against genital herpes in mice

PLoS pathogens, 2018-04, Vol.14 (4), p.e1006976-e1006976

2018

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Engineered lentivirus-derived nanoparticles (LVNPs) for delivery of CRISPR/Cas ribonucleoprotein complexes supporting base editing, prime editing and in vivo gene modification

Nucleic acids research, 2023-10, Vol.51 (18), p.10059-10074

2023

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Regulation of Steatohepatitis and PPARγ Signaling by Distinct AP-1 Dimers

Cell metabolism, 2014-01, Vol.19 (1), p.84-95

2014

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CRISPR/Cas9 model of prostate cancer identifies Kmt2c deficiency as a metastatic driver by Odam/Cabs1 gene cluster expression

Nature communications, 2024-03, Vol.15 (1), p.2088-2088, Article 2088

2024

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Liver carcinogenesis by FOS-dependent inflammation and cholesterol dysregulation

The Journal of experimental medicine, 2017-05, Vol.214 (5), p.1387-1409

2017

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β-catenin is required for prostate development and cooperates with Pten loss to drive invasive carcinoma

PLoS genetics, 2013-01, Vol.9 (1), p.e1003180

2013

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Dominant-negative SERPING1 variants cause intracellular retention of C1 inhibitor in hereditary angioedema

The Journal of clinical investigation, 2019-01, Vol.129 (1), p.388-405

2019

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The double-edge sword of CRISPR application for in vivo studies

Oncotarget, 2023-11, Vol.14 (1), p.919-920

Thomsen, Martin K.

2023

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In Vivo Application of CRISPR/Cas9 Revealed Implication of Foxa1 and Foxp1 in Prostate Cancer Proliferation and Epithelial Plasticity

Cancers, 2022-09, Vol.14 (18), p.4381

2022

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Comparative Analysis of Stk11/Lkb1 versus Pten Deficiency in Lung Adenocarcinoma Induced by CRISPR/Cas9

Cancers, 2021-02, Vol.13 (5), p.974

2021

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Activator protein 1 transcription factor fos‐related antigen 1 (fra‐1) is dispensable for murine liver fibrosis, but modulates xenobiotic metabolism

Hepatology (Baltimore, Md.), 2014-01, Vol.59 (1), p.261-273

2014

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Brca2 and Trp53 deficiency cooperate in the progression of mouse prostate tumourigenesis

PLoS genetics, 2010-06, Vol.6 (6), p.e1000995

2010

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A truncated reverse transcriptase enhances prime editing by split AAV vectors

Molecular therapy, 2022-09, Vol.30 (9), p.2942-2951

2022

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Liver cancer development driven by the AP-1/c-Jun~Fra-2 dimer through c-Myc

Proceedings of the National Academy of Sciences - PNAS, 2024-04, Vol.121 (18), p.e2404188121-e2404188121

2024

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STEEP mediates STING ER exit and activation of signaling

Nature immunology, 2020-08, Vol.21 (8), p.868-879

2020

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Treatment Represents a Key Driver of Metastatic Cancer Evolution

Cancer research (Chicago, Ill.), 2022-08, Vol.82 (16), p.2918-2927

2022

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Brain immune cells undergo cGAS/STING-dependent apoptosis during herpes simplex virus type 1 infection to limit type I IFN production

The Journal of clinical investigation, 2021-01, Vol.131 (1), p.1-17

2021

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In vivo CRISPR inactivation of Fos promotes prostate cancer progression by altering the associated AP-1 subunit Jun

Oncogene, 2021-04, Vol.40 (13), p.2437-2447

2021

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Three-dimensional culture models to study glioblastoma — current trends and future perspectives

Current opinion in pharmacology, 2021-12, Vol.61, p.91-97

2021

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Sensing of HSV-1 by the cGAS-STING pathway in microglia orchestrates antiviral defence in the CNS

Pre-Clinical Models to Study Human Prostate Cancer

The cGAS-STING pathway is a therapeutic target in a preclinical model of hepatocellular carcinoma

Lack of immunological DNA sensing in hepatocytes facilitates hepatitis B virus infection

Application of CRISPR for In Vivo Mouse Cancer Studies

Influenza A virus targets a cGAS-independent STING pathway that controls enveloped RNA viruses

STING agonists enable antiviral cross-talk between human cells and confer protection against genital herpes in mice

Engineered lentivirus-derived nanoparticles (LVNPs) for delivery of CRISPR/Cas ribonucleoprotein complexes supporting base editing, prime editing and in vivo gene modification

Regulation of Steatohepatitis and PPARγ Signaling by Distinct AP-1 Dimers

CRISPR/Cas9 model of prostate cancer identifies Kmt2c deficiency as a metastatic driver by Odam/Cabs1 gene cluster expression

Liver carcinogenesis by FOS-dependent inflammation and cholesterol dysregulation

β-catenin is required for prostate development and cooperates with Pten loss to drive invasive carcinoma

Dominant-negative SERPING1 variants cause intracellular retention of C1 inhibitor in hereditary angioedema

The double-edge sword of CRISPR application for in vivo studies

In Vivo Application of CRISPR/Cas9 Revealed Implication of Foxa1 and Foxp1 in Prostate Cancer Proliferation and Epithelial Plasticity

Comparative Analysis of Stk11/Lkb1 versus Pten Deficiency in Lung Adenocarcinoma Induced by CRISPR/Cas9

Activator protein 1 transcription factor fos‐related antigen 1 (fra‐1) is dispensable for murine liver fibrosis, but modulates xenobiotic metabolism

Brca2 and Trp53 deficiency cooperate in the progression of mouse prostate tumourigenesis

A truncated reverse transcriptase enhances prime editing by split AAV vectors

Liver cancer development driven by the AP-1/c-Jun~Fra-2 dimer through c-Myc

STEEP mediates STING ER exit and activation of signaling

Treatment Represents a Key Driver of Metastatic Cancer Evolution

Brain immune cells undergo cGAS/STING-dependent apoptosis during herpes simplex virus type 1 infection to limit type I IFN production

In vivo CRISPR inactivation of Fos promotes prostate cancer progression by altering the associated AP-1 subunit Jun

Three-dimensional culture models to study glioblastoma — current trends and future perspectives

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