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Therapy sculpts the complex interplay between cancer and the immune system during tumour evolution

Genome medicine, 2022-12, Vol.14 (1), p.137-137

2022

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Clonal Heterogeneity and Tumor Evolution: Past, Present, and the Future

Cell, 2017-02, Vol.168 (4), p.613-628

2017

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Cancer Evolution Constrained by the Immune Microenvironment

Cell, 2017-08, Vol.170 (5), p.825-827

2017

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Plk1 overexpression induces chromosomal instability and suppresses tumor development

Nature communications, 2018-08, Vol.9 (1), p.3012-14, Article 3012

2018

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Biological and Therapeutic Impact of Intratumor Heterogeneity in Cancer Evolution

Cancer cell, 2015-01, Vol.27 (1), p.15-26

2015

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Neoantigen-reactive CD8+ T cells affect clinical outcome of adoptive cell therapy with tumor-infiltrating lymphocytes in melanoma

The Journal of clinical investigation, 2022-01, Vol.132 (2)

2022

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Neoantigen quality, not quantity

Science translational medicine, 2019-08, Vol.11 (506)

2019

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Integrated transcriptome landscape of ALS identifies genome instability linked to TDP-43 pathology

Nature communications, 2023-04, Vol.14 (1), p.2176-2176, Article 2176

2023

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Tracking the evolution of esophageal squamous cell carcinoma under dynamic immune selection by multi-omics sequencing

Nature communications, 2023-02, Vol.14 (1), p.892-892, Article 892

2023

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Evolution of DNA methylome from precancerous lesions to invasive lung adenocarcinomas

Nature communications, 2021-01, Vol.12 (1), p.687-13, Article 687

2021

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Multiomics profiling of primary lung cancers and distant metastases reveals immunosuppression as a common characteristic of tumor cells with metastatic plasticity

Genome Biology, 2020-11, Vol.21 (1), p.271-21, Article 271

2020

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Germline ancestry influences the evolutionary disease course in lung adenocarcinomas

Evolutionary applications, 2020-08, Vol.13 (7), p.1550-1557

2020

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Oncogenic PIK3CA induces centrosome amplification and tolerance to genome doubling

Nature communications, 2017-11, Vol.8 (1), p.1773-15, Article 1773

2017

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Cold and heterogeneous T cell repertoire is associated with copy number aberrations and loss of immune genes in small-cell lung cancer

Nature communications, 2021-11, Vol.12 (1), p.6655-6655, Article 6655

2021

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Refphase: Multi-sample phasing reveals haplotype-specific copy number heterogeneity

PLoS computational biology, 2023-10, Vol.19 (10), p.e1011379-e1011379

2023

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Computational Analysis Reveals the Temporal Acquisition of Pathway Alterations during the Evolution of Cancer

Cancers, 2022-11, Vol.14 (23), p.5817

2022

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Persistence is key: Refining immunotherapy response prediction

Immunity (Cambridge, Mass.), 2023-03, Vol.56 (3), p.472-474

2023

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The importance of ancestry to understanding tumor mutation burden in cancer

Cancer cell, 2022-10, Vol.40 (10), p.1076-1078

2022

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ACT-Discover: identifying karyotype heterogeneity in pancreatic cancer evolution using ctDNA

Genome medicine, 2023-04, Vol.15 (1), p.27-27, Article 27

2023

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Author Correction: Multi-region exome sequencing reveals genomic evolution from preneoplasia to lung adenocarcinoma

Nature communications, 2021-05, Vol.12 (1), p.2888-2888, Article 2888

2021

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Cancer Genome Evolutionary Trajectories in Metastasis

Cancer cell, 2020-01, Vol.37 (1), p.8-19

2020

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Therapy sculpts the complex interplay between cancer and the immune system during tumour evolution

Clonal Heterogeneity and Tumor Evolution: Past, Present, and the Future

Cancer Evolution Constrained by the Immune Microenvironment

Plk1 overexpression induces chromosomal instability and suppresses tumor development

Biological and Therapeutic Impact of Intratumor Heterogeneity in Cancer Evolution

Neoantigen-reactive CD8+ T cells affect clinical outcome of adoptive cell therapy with tumor-infiltrating lymphocytes in melanoma

Multi-region exome sequencing reveals genomic evolution from preneoplasia to lung adenocarcinoma

Neoantigen quality, not quantity

Integrated transcriptome landscape of ALS identifies genome instability linked to TDP-43 pathology

Tracking the evolution of esophageal squamous cell carcinoma under dynamic immune selection by multi-omics sequencing

Evolution of DNA methylome from precancerous lesions to invasive lung adenocarcinomas

Multiomics profiling of primary lung cancers and distant metastases reveals immunosuppression as a common characteristic of tumor cells with metastatic plasticity

Germline ancestry influences the evolutionary disease course in lung adenocarcinomas

MCL-1 gains occur with high frequency in lung adenocarcinoma and can be targeted therapeutically

Clonal somatic copy number altered driver events inform drug sensitivity in high-grade serous ovarian cancer

Identifying key questions in the ecology and evolution of cancer

Oncogenic PIK3CA induces centrosome amplification and tolerance to genome doubling

Cold and heterogeneous T cell repertoire is associated with copy number aberrations and loss of immune genes in small-cell lung cancer

Refphase: Multi-sample phasing reveals haplotype-specific copy number heterogeneity

Computational Analysis Reveals the Temporal Acquisition of Pathway Alterations during the Evolution of Cancer

Persistence is key: Refining immunotherapy response prediction

The importance of ancestry to understanding tumor mutation burden in cancer

ACT-Discover: identifying karyotype heterogeneity in pancreatic cancer evolution using ctDNA

Author Correction: Multi-region exome sequencing reveals genomic evolution from preneoplasia to lung adenocarcinoma

Cancer Genome Evolutionary Trajectories in Metastasis

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