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Dynamic dissociating homo-oligomers and the control of protein function

Archives of biochemistry and biophysics, 2012-03, Vol.519 (2), p.131-143

2012

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Advancement of the 5-Amino-1-(Carbamoylmethyl)-1H-1,2,3-Triazole-4-Carboxamide Scaffold to Disarm the Bacterial SOS Response

Frontiers in microbiology, 2018-12, Vol.9, p.2961

2018

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Allosteric Inhibition of Human Porphobilinogen Synthase

The Journal of biological chemistry, 2009-12, Vol.284 (51), p.35807-35817

2009

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Evidence for diversity of substrate specificity among members of the chymase family of serine proteases

FEBS letters, 2002-02, Vol.512 (1), p.133-138

2002

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Inhibitors of LexA Autoproteolysis and the Bacterial SOS Response Discovered by an Academic–Industry Partnership

ACS infectious diseases, 2018-03, Vol.4 (3), p.349-359

2018

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Kinetics and Thermodynamics of the Interchange of the Morpheein Forms of Human Porphobilinogen Synthase

Biochemistry (Easton), 2008-03, Vol.47 (10), p.3245-3257

2008

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Protein quaternary structure focus for small molecule allosteric control

The FASEB journal, 2010-04, Vol.24 (S1), p.913.1-913.1

2010

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Diverse Effects of pH on the Inhibition of Human Chymase by Serpins

The Journal of biological chemistry, 1997-09, Vol.272 (39), p.24499-24507

1997

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Diverse Clinical Compounds Alter the Quaternary Structure and Inhibit the Activity of an Essential Enzyme

ChemMedChem, 2011-06, Vol.6 (6), p.1067-1073

2011

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Acinetobacter baumannii OxPhos inhibitors as selective anti-infective agents

Bioorganic & medicinal chemistry letters, 2015-01, Vol.25 (2), p.378-383

2015

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Binding and modification of proteins by methylglyoxal under physiological conditions. A kinetic and mechanistic study with N alpha-acetylarginine, N alpha-acetylcysteine, and N alpha-acetyllysine, and bovine serum albumin

The Journal of biological chemistry, 1994-12, Vol.269 (51), p.32299-32305

1994

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Shape‐shifting proteins with a potential link to drug side effects

The FASEB journal, 2010-04, Vol.24 (S1), p.907.5-907.5

2010

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Counterarguments

Early music, 1999-05, Vol.27 (2), p.349-350

Selwood, Trevor L.

1999

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X-ray Structures of Free and Leupeptin-complexed Human αI-Tryptase Mutants: Indication for an α→β-Tryptase Transition

Journal of molecular biology, 2006-03, Vol.357 (1), p.195-209

2006

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Characterization of Three Distinct Catalytic Forms of Human Tryptase-β: Their Interrelationships and Relevance

Biochemistry (Easton), 2007-08, Vol.46 (33), p.9615-9629

2007

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Calcium-Dependent Conformation of Desmoglein 1 Is Required for its Cleavage by Exfoliative Toxin

Journal of investigative dermatology, 2003-08, Vol.121 (2), p.383-389

2003

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Kinetics and Thermodynamics of the Interchange of the Morpheein Forms of Human Porphobilinogen Synthase super([dagger])

Biochemistry (Easton), 2008-01, Vol.47 (10), p.3245-3257

2008

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The Interaction of Human Tryptase-β with Small Molecule Inhibitors Provides New Insights into the Unusual Functional Instability and Quaternary Structure of the Protease

Biochemistry (Easton), 2005-03, Vol.44 (9), p.3580-3590

2005

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Diverse Stability and Catalytic Properties of Human Tryptase α and β Isoforms are Mediated by Residue Differences at the S1 Pocket

Biochemistry (Easton), 2002-03, Vol.41 (10), p.3329-3340

2002

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X-ray structures of free and leupeptin-complexed human alphaI-tryptase mutants: indication for an alpha-->beta-tryptase transition

Journal of molecular biology, 2006-03, Vol.357 (1), p.195-209

2006

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Potent bivalent inhibition of human tryptase-beta by a synthetic inhibitor

Biological chemistry, 2003-12, Vol.384 (12), p.1605-1611

2003

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Heterogeneity in Serpin−Protease Complexes As Demonstrated by Differences in the Mechanism of Complex Breakdown

Biochemistry (Easton), 2002-01, Vol.41 (1), p.334-342

2002

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The reaction of methylglyoxal with aminoguanidine under physiological conditions and prevention of methylglyoxal binding to plasma proteins

Biochemical pharmacology, 1994-11, Vol.48 (10), p.1865-1870

1994

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Recombinant Expression of Human Mast Cell Proteases Chymase and Tryptase

Biological chemistry, 1998, Vol.379 (2), p.167-174

1998

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Counteraguments

Early music, 1999-05, Vol.XXVII (2), p.349-350

SELWOOD, TREVOR L

1999

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Dynamic dissociating homo-oligomers and the control of protein function

Advancement of the 5-Amino-1-(Carbamoylmethyl)-1H-1,2,3-Triazole-4-Carboxamide Scaffold to Disarm the Bacterial SOS Response

Allosteric Inhibition of Human Porphobilinogen Synthase

Evidence for diversity of substrate specificity among members of the chymase family of serine proteases

Inhibitors of LexA Autoproteolysis and the Bacterial SOS Response Discovered by an Academic–Industry Partnership

Kinetics and Thermodynamics of the Interchange of the Morpheein Forms of Human Porphobilinogen Synthase

Protein quaternary structure focus for small molecule allosteric control

Diverse Effects of pH on the Inhibition of Human Chymase by Serpins

Diverse Clinical Compounds Alter the Quaternary Structure and Inhibit the Activity of an Essential Enzyme

Acinetobacter baumannii OxPhos inhibitors as selective anti-infective agents

Binding and modification of proteins by methylglyoxal under physiological conditions. A kinetic and mechanistic study with N alpha-acetylarginine, N alpha-acetylcysteine, and N alpha-acetyllysine, and bovine serum albumin

Shape‐shifting proteins with a potential link to drug side effects

Counterarguments

X-ray Structures of Free and Leupeptin-complexed Human αI-Tryptase Mutants: Indication for an α→β-Tryptase Transition

Characterization of Three Distinct Catalytic Forms of Human Tryptase-β: Their Interrelationships and Relevance

Calcium-Dependent Conformation of Desmoglein 1 Is Required for its Cleavage by Exfoliative Toxin

Kinetics and Thermodynamics of the Interchange of the Morpheein Forms of Human Porphobilinogen Synthase super([dagger])

The Interaction of Human Tryptase-β with Small Molecule Inhibitors Provides New Insights into the Unusual Functional Instability and Quaternary Structure of the Protease

Diverse Stability and Catalytic Properties of Human Tryptase α and β Isoforms are Mediated by Residue Differences at the S1 Pocket

X-ray structures of free and leupeptin-complexed human alphaI-tryptase mutants: indication for an alpha-->beta-tryptase transition

Potent bivalent inhibition of human tryptase-beta by a synthetic inhibitor

Heterogeneity in Serpin−Protease Complexes As Demonstrated by Differences in the Mechanism of Complex Breakdown

The reaction of methylglyoxal with aminoguanidine under physiological conditions and prevention of methylglyoxal binding to plasma proteins

Recombinant Expression of Human Mast Cell Proteases Chymase and Tryptase

Counteraguments

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