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Genetic and Epigenetic Mechanisms in Metal Carcinogenesis and Cocarcinogenesis: Nickel, Arsenic, and Chromium

Chemical research in toxicology, 2008-01, Vol.21 (1), p.28-44

2008

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Role of iron in cancer

Seminars in cancer biology, 2021-11, Vol.76, p.189-194

Salnikow, Konstantin

2021

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HIF-1, An Oxygen and Metal Responsive Transcription Factor

Cancer biology & therapy, 2004-01, Vol.3 (1), p.29-35

2004

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Depletion of Intracellular Ascorbate by the Carcinogenic Metals Nickel and Cobalt Results in the Induction of Hypoxic Stress

The Journal of biological chemistry, 2004-09, Vol.279 (39), p.40337-40344

2004

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Downregulation of major histocompatibility complex antigens in invading glioma cells: stealth invasion of the brain

Laboratory investigation, 2005-03, Vol.85 (3), p.328-341

2005

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The Regulation of Hypoxic Genes by Calcium Involves c-Jun/AP-1, Which Cooperates with Hypoxia-Inducible Factor 1 in Response to Hypoxia

Molecular and Cellular Biology, 2002-03, Vol.22 (6), p.1734-1741

2002

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Ascorbate depletion mediates up-regulation of hypoxia-associated proteins by cell density and nickel

Journal of cellular biochemistry, 2006-04, Vol.97 (5), p.1025-1035

2006

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α-Latrotoxin Stimulates Exocytosis by the Interaction with a Neuronal G-Protein-Coupled Receptor

Neuron (Cambridge, Mass.), 1997-06, Vol.18 (6), p.925-937

1997

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Role of Ca2+ in the Regulation of Nickel-Inducible Cap43 Gene Expression

Toxicology and applied pharmacology, 1999-10, Vol.160 (2), p.127-132

1999

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Nickel carcinogenesis

Mutation research, 2003-12, Vol.533 (1-2), p.67

2003

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Two novel VHL targets, TGFBI (BIGH3) and its transactivator KLF10, are up-regulated in renal clear cell carcinoma and other tumors

Biochemical and biophysical research communications, 2008-06, Vol.370 (4), p.536-540

2008

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The role of ascorbate in the modulation of HIF-1α protein and HIF-dependent transcription by chromium(VI) and nickel(II)

Free radical biology & medicine, 2007-04, Vol.42 (8), p.1246-1257

2007

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The involvement of hypoxia-inducible transcription factor-1-dependent pathway in nickel carcinogenesis

Cancer research (Chicago, Ill.), 2003-07, Vol.63 (13), p.3524-3530

2003

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Metal Ions-Stimulated Iron Oxidation in Hydroxylases Facilitates Stabilization of HIF-1α Protein

Toxicological sciences, 2009-02, Vol.107 (2), p.394-403

2009

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Effect of nickel and iron co-exposure on human lung cells

Toxicology and applied pharmacology, 2004-04, Vol.196 (2), p.258-265

2004

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Hypoxia inducible factor-1 alpha-independent suppression of aryl hydrocarbon receptor-regulated genes by nickel

Molecular pharmacology, 2003-12, Vol.64 (6), p.1485-1493

2003

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Hyperinducibility of hypoxia-responsive genes without p53/p21-dependent checkpoint in aggressive prostate cancer

Cancer research (Chicago, Ill.), 2000-10, Vol.60 (20), p.5630-5634

2000

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Molecular Mechanisms in Nickel Carcinogenesis: Modeling Ni(II) Binding Site in Histone H4

Environmental health perspectives, 2002-10, Vol.110 (suppl 5), p.719-723

2002

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Role of Ca(2+) in the regulation of nickel-inducible Cap43 gene expression

Toxicology and applied pharmacology, 1999-10, Vol.160 (2), p.127-132

1999

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MAGE-11 inhibits the hypoxia-inducible factor prolyl hydroxylase PHD2 and activates hypoxic response

Cancer research (Chicago, Ill.), 2009-01, Vol.69 (2), p.616-624

2009

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Quantum Chemical Modeling of Reaction Mechanism for 2-Oxoglutarate Dependent Enzymes: Effect of Substitution of Iron by Nickel and Cobalt

The journal of physical chemistry. A, Molecules, spectroscopy, kinetics, environment, & general theory, 2006-03, Vol.110 (12), p.4223-4228

2006

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Interaction of Ni(II) and Cu(II) with a metal binding sequence of histone H4: AKRHRK, a model of the H4 tail

Biochimica et biophysica acta, 2000-07, Vol.1475 (2), p.163-168

2000

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Epigenetic mechanisms of nickel carcinogenesis

Journal of environmental pathology, toxicology and oncology, 2000, Vol.19 (3), p.307

2000

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Genetic and Epigenetic Mechanisms in Metal Carcinogenesis and Cocarcinogenesis: Nickel, Arsenic, and Chromium

Role of iron in cancer

HIF-1, An Oxygen and Metal Responsive Transcription Factor

Depletion of Intracellular Ascorbate by the Carcinogenic Metals Nickel and Cobalt Results in the Induction of Hypoxic Stress

Downregulation of major histocompatibility complex antigens in invading glioma cells: stealth invasion of the brain

The Regulation of Hypoxic Genes by Calcium Involves c-Jun/AP-1, Which Cooperates with Hypoxia-Inducible Factor 1 in Response to Hypoxia

Ascorbate depletion mediates up-regulation of hypoxia-associated proteins by cell density and nickel

α-Latrotoxin Stimulates Exocytosis by the Interaction with a Neuronal G-Protein-Coupled Receptor

Ferroptosis: A Regulated Cell Death Nexus Linking Metabolism, Redox Biology, and Disease

Role of Ca2+ in the Regulation of Nickel-Inducible Cap43 Gene Expression

Nickel carcinogenesis

A path to translation: How 3D patient tumor avatars enable next generation precision oncology

Two novel VHL targets, TGFBI (BIGH3) and its transactivator KLF10, are up-regulated in renal clear cell carcinoma and other tumors

The role of ascorbate in the modulation of HIF-1α protein and HIF-dependent transcription by chromium(VI) and nickel(II)

The involvement of hypoxia-inducible transcription factor-1-dependent pathway in nickel carcinogenesis

Metal Ions-Stimulated Iron Oxidation in Hydroxylases Facilitates Stabilization of HIF-1α Protein

Effect of nickel and iron co-exposure on human lung cells

Hypoxia inducible factor-1 alpha-independent suppression of aryl hydrocarbon receptor-regulated genes by nickel

Hyperinducibility of hypoxia-responsive genes without p53/p21-dependent checkpoint in aggressive prostate cancer

Molecular Mechanisms in Nickel Carcinogenesis: Modeling Ni(II) Binding Site in Histone H4

Role of Ca(2+) in the regulation of nickel-inducible Cap43 gene expression

MAGE-11 inhibits the hypoxia-inducible factor prolyl hydroxylase PHD2 and activates hypoxic response

Quantum Chemical Modeling of Reaction Mechanism for 2-Oxoglutarate Dependent Enzymes: Effect of Substitution of Iron by Nickel and Cobalt

Interaction of Ni(II) and Cu(II) with a metal binding sequence of histone H4: AKRHRK, a model of the H4 tail

Epigenetic mechanisms of nickel carcinogenesis

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