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Depletion of Intracellular Ascorbate by the Carcinogenic Metals Nickel and Cobalt Results in the Induction of Hypoxic Stress

The Journal of biological chemistry, 2004-09, Vol.279 (39), p.40337-40344

2004

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Induction of oxidative DNA damage by carcinogenic metals

Toxicology letters, 2002-02, Vol.127 (1), p.55-62

2002

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A profile of 8-oxo-dGTPase activities in the NCI-60 human cancer panel: Meta-analytic insight into the regulation and role of MTH1 (NUDT1) gene expression in carcinogenesis

Free radical biology & medicine, 2020-02, Vol.148, p.1-21

2020

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Effects of ascorbic acid on carcinogenicity and acute toxicity of nickel subsulfide, and on tumor transplants growth in gulonolactone oxidase knock-out mice and wild-type C57BL mice

Toxicology and applied pharmacology, 2011-11, Vol.257 (1), p.32-37

2011

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Ascorbate depletion mediates up-regulation of hypoxia-associated proteins by cell density and nickel

Journal of cellular biochemistry, 2006-04, Vol.97 (5), p.1025-1035

2006

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Low level, long‐term inorganic arsenite exposure causes generalized resistance to apoptosis in cultured human keratinocytes: Potential role in skin co‐carcinogenesis

International journal of cancer, 2005-08, Vol.116 (1), p.20-26

2005

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Ontogeny-driven rDNA rearrangement, methylation, and transcription, and paternal influence

PloS one, 2011-07, Vol.6 (7), p.e22266

2011

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Nickel carcinogenesis

Mutation research, 2003-12, Vol.533 (1-2), p.67

2003

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Oxidative DNA and protein damage in metal-induced toxicity and carcinogenesis

Free radical biology & medicine, 2002-05, Vol.32 (10), p.958-967

Kasprzak, Kazimierz S

2002

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Hypersusceptibility to cisplatin carcinogenicity in metallothionein‐I/II double knockout mice: Production of hepatocellular carcinoma at clinically relevant doses

International journal of cancer, 2006-07, Vol.119 (1), p.28-32

2006

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DNA Deaminating Ability and Genotoxicity of Nitric Oxide and Its Progenitors

Science (American Association for the Advancement of Science), 1991-11, Vol.254 (5034), p.1001-1003

1991

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The role of oxidative damage in metal carcinogenicity

Chemical research in toxicology, 1991-11, Vol.4 (6), p.604-615

Kasprzak, Kazimierz S

1991

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Inhibition of 8-oxo-2′-deoxyguanosine 5′-triphosphate pyrophosphohydrolase (8-oxo-dGTPase) activity of the antimutagenic human MTH1 protein by nucleoside 5′-diphosphates

Free radical biology & medicine, 2003-09, Vol.35 (6), p.595-602

2003

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Ascorbate Depletion: A Critical Step in Nickel Carcinogenesis?

Environmental health perspectives, 2005-05, Vol.113 (5), p.577-584

2005

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Binding of Nickel(II) and Copper(II) to the N-Terminal Sequence of Human Protamine HP2

Chemical research in toxicology, 1997-08, Vol.10 (8), p.906-914

1997

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The role of ascorbate in the modulation of HIF-1α protein and HIF-dependent transcription by chromium(VI) and nickel(II)

Free radical biology & medicine, 2007-04, Vol.42 (8), p.1246-1257

2007

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Ni(II) affects ubiquitination of core histones H2B and H2A

Experimental cell research, 2006-10, Vol.312 (17), p.3252-3259

2006

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Up-regulation of 8-oxo-dGTPase activity of MTH1 protein in the brain, testes and kidneys of mice exposed to (137)Cs gamma radiation

Radiation research, 2009-08, Vol.172 (2), p.187-197

2009

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Metal Ions-Stimulated Iron Oxidation in Hydroxylases Facilitates Stabilization of HIF-1α Protein

Toxicological sciences, 2009-02, Vol.107 (2), p.394-403

2009

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Regulation of hypoxia-inducible genes by ETS1 transcription factor

Carcinogenesis (New York), 2008-08, Vol.29 (8), p.1493-1499

2008

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Genotoxicity of metal ions: chemical insights

Metal ions in life sciences, 2011, Vol.8, p.319

2011

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Truncation, Deamidation, and Oxidation of Histone H2B in Cells Cultured with Nickel(II)

Chemical research in toxicology, 2005-12, Vol.18 (12), p.1934-1942

2005

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In Vitro Inhibition of the Enzymatic Activity of Tumor Suppressor FHIT Gene Product by Carcinogenic Transition Metals

Chemical research in toxicology, 2002-03, Vol.15 (3), p.319-325

2002

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DNA damage, superoxide, and mutant K-ras in human lung adenocarcinoma cells

Free radical biology & medicine, 2007-10, Vol.43 (8), p.1145-1155

2007

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Determination of the stability constants and oxidation susceptibility of nickel(II) complexes with 2′-deoxyguanosine 5′-triphosphate and l-histidine

Journal of inorganic biochemistry, 2005-03, Vol.99 (3), p.737-746

2005

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Depletion of Intracellular Ascorbate by the Carcinogenic Metals Nickel and Cobalt Results in the Induction of Hypoxic Stress

Induction of oxidative DNA damage by carcinogenic metals

A profile of 8-oxo-dGTPase activities in the NCI-60 human cancer panel: Meta-analytic insight into the regulation and role of MTH1 (NUDT1) gene expression in carcinogenesis

Effects of ascorbic acid on carcinogenicity and acute toxicity of nickel subsulfide, and on tumor transplants growth in gulonolactone oxidase knock-out mice and wild-type C57BL mice

Ascorbate depletion mediates up-regulation of hypoxia-associated proteins by cell density and nickel

Low level, long‐term inorganic arsenite exposure causes generalized resistance to apoptosis in cultured human keratinocytes: Potential role in skin co‐carcinogenesis

Ontogeny-driven rDNA rearrangement, methylation, and transcription, and paternal influence

Nickel carcinogenesis

Oxidative DNA and protein damage in metal-induced toxicity and carcinogenesis

Hypersusceptibility to cisplatin carcinogenicity in metallothionein‐I/II double knockout mice: Production of hepatocellular carcinoma at clinically relevant doses

DNA Deaminating Ability and Genotoxicity of Nitric Oxide and Its Progenitors

The role of oxidative damage in metal carcinogenicity

Inhibition of 8-oxo-2′-deoxyguanosine 5′-triphosphate pyrophosphohydrolase (8-oxo-dGTPase) activity of the antimutagenic human MTH1 protein by nucleoside 5′-diphosphates

Ascorbate Depletion: A Critical Step in Nickel Carcinogenesis?

Binding of Nickel(II) and Copper(II) to the N-Terminal Sequence of Human Protamine HP2

The role of ascorbate in the modulation of HIF-1α protein and HIF-dependent transcription by chromium(VI) and nickel(II)

Ni(II) affects ubiquitination of core histones H2B and H2A

Up-regulation of 8-oxo-dGTPase activity of MTH1 protein in the brain, testes and kidneys of mice exposed to (137)Cs gamma radiation

Metal Ions-Stimulated Iron Oxidation in Hydroxylases Facilitates Stabilization of HIF-1α Protein

Regulation of hypoxia-inducible genes by ETS1 transcription factor

Genotoxicity of metal ions: chemical insights

Truncation, Deamidation, and Oxidation of Histone H2B in Cells Cultured with Nickel(II)

In Vitro Inhibition of the Enzymatic Activity of Tumor Suppressor FHIT Gene Product by Carcinogenic Transition Metals

DNA damage, superoxide, and mutant K-ras in human lung adenocarcinoma cells

Determination of the stability constants and oxidation susceptibility of nickel(II) complexes with 2′-deoxyguanosine 5′-triphosphate and l-histidine

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