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Liver X receptor biology and pharmacology: new pathways, challenges and opportunities

Trends in pharmacological sciences (Regular ed.), 2012-07, Vol.33 (7), p.394-404

2012

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The oxysterol-CXCR2 axis plays a key role in the recruitment of tumor-promoting neutrophils

The Journal of experimental medicine, 2013-08, Vol.210 (9), p.1711-1728

2013

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LXR‐dependent and ‐independent effects of oxysterols on immunity and tumor growth

European journal of immunology, 2014-07, Vol.44 (7), p.1896-1903

2014

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Genome-Wide Profiling of Liver X Receptor, Retinoid X Receptor, and Peroxisome Proliferator-Activated Receptor α in Mouse Liver Reveals Extensive Sharing of Binding Sites

Molecular and Cellular Biology, 2012-02, Vol.32 (4), p.852-867

2012

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Are Synthetic Compounds that Silence the Liver-X-Receptor the Next Generation of Anti-cancer Drugs?

Cancer cell, 2015-07, Vol.28 (1), p.3-4

Steffensen, Knut R.

2015

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Insights From Liver‐Humanized Mice on Cholesterol Lipoprotein Metabolism and LXR‐Agonist Pharmacodynamics in Humans

Hepatology (Baltimore, Md.), 2020-08, Vol.72 (2), p.656-670

2020

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Emerging role of thyroid hormone metabolites

Acta Physiologica, 2016-07, Vol.217 (3), p.184-216

2016

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The oxysterol receptor LXR inhibits proliferation of human breast cancer cells

Carcinogenesis (New York), 2009-04, Vol.30 (4), p.575-579

2009

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Liver X receptor regulation of thyrotropin-releasing hormone transcription in mouse hypothalamus is dependent on thyroid status

PloS one, 2014-09, Vol.9 (9), p.e106983-e106983

2014

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Hepatic ACAT2 knock down increases ABCA1 and modifies HDL metabolism in mice

PloS one, 2014-04, Vol.9 (4), p.e93552-e93552

2014

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Liver X receptors contribute to the protective immune response against Mycobacterium tuberculosis in mice

The Journal of clinical investigation, 2009-06, Vol.119 (6), p.1626-1637

2009

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Liver × receptor ligands disrupt breast cancer cell proliferation through an E2F-mediated mechanism

Breast cancer research : BCR, 2013-06, Vol.15 (3), p.R51-R51, Article R51

2013

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Routine noninvasive prenatal screening for fetal RHD in plasma of RhD-negative pregnant women-2 years of screening experience from Denmark

Prenatal diagnosis, 2014-10, Vol.34 (10), p.1000-1005

2014

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Soy protein isoflavones differentially regulate liver X receptor isoforms to modulate lipid metabolism and cholesterol transport in the liver and intestine in mice

Diabetologia, 2012-09, Vol.55 (9), p.2469-2478

2012

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Srebf1 Controls Midbrain Dopaminergic Neurogenesis

Cell reports (Cambridge), 2020-05, Vol.31 (5), p.107601-107601, Article 107601

2020

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Putative Metabolic Effects of the Liver X Receptor (LXR)

Diabetes (New York, N.Y.), 2004-02, Vol.53 (suppl 1), p.S36-S42

2004

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Liver X receptor regulates hepatic nuclear O-GlcNAc signaling and carbohydrate responsive element-binding protein activity[S]

Journal of lipid research, 2015-04, Vol.56 (4), p.771-785

2015

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High MBL-expressing genotypes are associated with deterioration in renal function in type 2 diabetes

Frontiers in immunology, 2022-12, Vol.13, p.1080388-1080388

2022

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Critical role of astroglial apolipoprotein E and liver X receptor-α expression for microglial Aβ phagocytosis

The Journal of neuroscience, 2011-05, Vol.31 (19), p.7049-7059

2011

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Genome-wide landscape of liver X receptor chromatin binding and gene regulation in human macrophages

BMC genomics, 2012-01, Vol.13 (1), p.50-50, Article 50

2012

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Myelin-derived lipids modulate macrophage activity by liver X receptor activation

PloS one, 2012-09, Vol.7 (9), p.e44998-e44998

2012

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Liver X Receptor Alpha Is Important in Maintaining Blood-Brain Barrier Function

Frontiers in immunology, 2019-07, Vol.10, p.1811-1811

2019

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Maternal carriage of H-Y restricting HLA class II alleles is a negative prognostic factor for women with recurrent pregnancy loss after birth of a boy

Journal of reproductive immunology, 2023-03, Vol.156, p.103817-103817, Article 103817

2023

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Tumor-mediated liver X receptor-α activation inhibits CC chemokine receptor-7 expression on dendritic cells and dampens antitumor responses

Nature medicine, 2010-01, Vol.16 (1), p.98-105

2010

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Liver X receptor biology and pharmacology: new pathways, challenges and opportunities

The oxysterol-CXCR2 axis plays a key role in the recruitment of tumor-promoting neutrophils

LXR‐dependent and ‐independent effects of oxysterols on immunity and tumor growth

Genome-Wide Profiling of Liver X Receptor, Retinoid X Receptor, and Peroxisome Proliferator-Activated Receptor α in Mouse Liver Reveals Extensive Sharing of Binding Sites

Antiproliferative effects and mechanisms of liver X receptor ligands in pancreatic ductal adenocarcinoma cells

Are Synthetic Compounds that Silence the Liver-X-Receptor the Next Generation of Anti-cancer Drugs?

Insights From Liver‐Humanized Mice on Cholesterol Lipoprotein Metabolism and LXR‐Agonist Pharmacodynamics in Humans

Emerging role of thyroid hormone metabolites

The oxysterol receptor LXR inhibits proliferation of human breast cancer cells

Liver X receptor regulation of thyrotropin-releasing hormone transcription in mouse hypothalamus is dependent on thyroid status

Hepatic ACAT2 knock down increases ABCA1 and modifies HDL metabolism in mice

Liver X receptors contribute to the protective immune response against Mycobacterium tuberculosis in mice

Liver × receptor ligands disrupt breast cancer cell proliferation through an E2F-mediated mechanism

Routine noninvasive prenatal screening for fetal RHD in plasma of RhD-negative pregnant women-2 years of screening experience from Denmark

Soy protein isoflavones differentially regulate liver X receptor isoforms to modulate lipid metabolism and cholesterol transport in the liver and intestine in mice

Srebf1 Controls Midbrain Dopaminergic Neurogenesis

Putative Metabolic Effects of the Liver X Receptor (LXR)

Liver X receptor regulates hepatic nuclear O-GlcNAc signaling and carbohydrate responsive element-binding protein activity[S]

High MBL-expressing genotypes are associated with deterioration in renal function in type 2 diabetes

Critical role of astroglial apolipoprotein E and liver X receptor-α expression for microglial Aβ phagocytosis

Genome-wide landscape of liver X receptor chromatin binding and gene regulation in human macrophages

Myelin-derived lipids modulate macrophage activity by liver X receptor activation

Liver X Receptor Alpha Is Important in Maintaining Blood-Brain Barrier Function

Maternal carriage of H-Y restricting HLA class II alleles is a negative prognostic factor for women with recurrent pregnancy loss after birth of a boy

Tumor-mediated liver X receptor-α activation inhibits CC chemokine receptor-7 expression on dendritic cells and dampens antitumor responses

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