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Inflammation and its resolution in atherosclerosis: mediators and therapeutic opportunities

Nature reviews cardiology, 2019-07, Vol.16 (7), p.389-406

2019

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Cholesterol crystals activate the NLRP3 inflammasome in human macrophages: a novel link between cholesterol metabolism and inflammation

PloS one, 2010-07, Vol.5 (7), p.e11765-e11765

2010

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Angptl3 deficiency is associated with increased insulin sensitivity, lipoprotein lipase activity, and decreased serum free fatty acids

Arteriosclerosis, thrombosis, and vascular biology, 2013-07, Vol.33 (7), p.1706

2013

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Extracellular Acidosis Is a Novel Danger Signal Alerting Innate Immunity via the NLRP3 Inflammasome

The Journal of biological chemistry, 2013-05, Vol.288 (19), p.13410-13419

2013

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PCSK9 inhibition alters the lipidome of plasma and lipoprotein fractions

Atherosclerosis, 2018-02, Vol.269, p.159-165

2018

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The profile of cholesterol metabolism does not interfere with the cholesterol-lowering efficacy of phytostanol esters

Clinical nutrition (Edinburgh, Scotland), 2024-03, Vol.43 (3), p.587-592

2024

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High cholesterol absorption: A risk factor of atherosclerotic cardiovascular diseases?

Atherosclerosis, 2023-07, Vol.376, p.53-62

2023

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OxLDL sensitizes platelets for increased formation of extracellular vesicles capable of finetuning macrophage gene expression

European journal of cell biology, 2023-06, Vol.102 (2), p.151311-151311, Article 151311

2023

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Serum amyloid A activates the NLRP3 inflammasome via P2X7 receptor and a cathepsin B-sensitive pathway

The Journal of immunology (1950), 2011-06, Vol.186 (11), p.6119-6128

2011

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Why and how increased plasma ceramides predict future cardiovascular events?

Atherosclerosis, 2020-12, Vol.314, p.71-73

2020

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Aggregation Susceptibility of Low-Density Lipoproteins-A Novel Modifiable Biomarker of Cardiovascular Risk

Journal of clinical medicine, 2021-04, Vol.10 (8), p.1769

2021

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Extracellular Lipids Accumulate in Human Carotid Arteries as Distinct Three-Dimensional Structures and Have Proinflammatory Properties

The American journal of pathology, 2018-02, Vol.188 (2), p.525-538

2018

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Carboxyl-Terminal Cleavage of Apolipoprotein A-I by Human Mast Cell Chymase Impairs Its Anti-Inflammatory Properties

Arteriosclerosis, thrombosis, and vascular biology, 2016-02, Vol.36 (2), p.274

2016

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Potential pathological roles for oxidized low-density lipoprotein and scavenger receptors SR-AI, CD36, and LOX-1 in aortic valve stenosis

Atherosclerosis, 2014-08, Vol.235 (2), p.398-407

2014

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Modified Lipoproteins Induce Arterial Wall Inflammation During Atherogenesis

Frontiers in cardiovascular medicine, 2022-03, Vol.9, p.841545-841545

2022

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Insights From Liver‐Humanized Mice on Cholesterol Lipoprotein Metabolism and LXR‐Agonist Pharmacodynamics in Humans

Hepatology (Baltimore, Md.), 2020-08, Vol.72 (2), p.656-670

2020

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Acidic extracellular pH promotes accumulation of free cholesterol in human monocyte-derived macrophages via inhibition of ACAT1 activity

Atherosclerosis, 2020-11, Vol.312, p.1-7

2020

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The effect of intakes of fish and Camelina sativa oil on atherogenic and anti-atherogenic functions of LDL and HDL particles: A randomized controlled trial

Atherosclerosis, 2019-02, Vol.281, p.56-61

2019

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Neutrophil proteinase 3 — An LDL- and HDL-proteolyzing enzyme with a potential to contribute to cholesterol accumulation in human atherosclerotic lesions

Biochimica et biophysica acta. Molecular and cell biology of lipids, 2022-12, Vol.1867 (12), p.159225-159225, Article 159225

2022

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The human liver lipidome is significantly related to the lipid composition and aggregation susceptibility of low-density lipoprotein (LDL) particles

Atherosclerosis, 2022-12, Vol.363, p.22-29

2022

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Cathepsin G activity lowers plasma LDL and reduces atherosclerosis

Biochimica et biophysica acta. Molecular basis of disease, 2014-11, Vol.1842 (11), p.2174-2183

2014

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Vasculoprotective properties of plasma lipoproteins from brown bears (Ursus arctos)

Journal of lipid research, 2021-01, Vol.62, p.100065, Article 100065

2021

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Low-density lipoprotein aggregation predicts adverse cardiovascular events in peripheral artery disease

Atherosclerosis, 2021-01, Vol.316, p.53-57

2021

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The year 2020 in Atherosclerosis

Atherosclerosis, 2021-06, Vol.326, p.35-44

2021

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Modified lipoprotein-derived lipid particles accumulate in human stenotic aortic valves

PloS one, 2013-06, Vol.8 (6), p.e65810-e65810

2013

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Inflammation and its resolution in atherosclerosis: mediators and therapeutic opportunities

Cholesterol crystals activate the NLRP3 inflammasome in human macrophages: a novel link between cholesterol metabolism and inflammation

Angptl3 deficiency is associated with increased insulin sensitivity, lipoprotein lipase activity, and decreased serum free fatty acids

Extracellular Acidosis Is a Novel Danger Signal Alerting Innate Immunity via the NLRP3 Inflammasome

PCSK9 inhibition alters the lipidome of plasma and lipoprotein fractions

The profile of cholesterol metabolism does not interfere with the cholesterol-lowering efficacy of phytostanol esters

High cholesterol absorption: A risk factor of atherosclerotic cardiovascular diseases?

OxLDL sensitizes platelets for increased formation of extracellular vesicles capable of finetuning macrophage gene expression

Serum amyloid A activates the NLRP3 inflammasome via P2X7 receptor and a cathepsin B-sensitive pathway

Why and how increased plasma ceramides predict future cardiovascular events?

Aggregation Susceptibility of Low-Density Lipoproteins-A Novel Modifiable Biomarker of Cardiovascular Risk

Extracellular Lipids Accumulate in Human Carotid Arteries as Distinct Three-Dimensional Structures and Have Proinflammatory Properties

Carboxyl-Terminal Cleavage of Apolipoprotein A-I by Human Mast Cell Chymase Impairs Its Anti-Inflammatory Properties

Potential pathological roles for oxidized low-density lipoprotein and scavenger receptors SR-AI, CD36, and LOX-1 in aortic valve stenosis

Modified Lipoproteins Induce Arterial Wall Inflammation During Atherogenesis

Insights From Liver‐Humanized Mice on Cholesterol Lipoprotein Metabolism and LXR‐Agonist Pharmacodynamics in Humans

Acidic extracellular pH promotes accumulation of free cholesterol in human monocyte-derived macrophages via inhibition of ACAT1 activity

The effect of intakes of fish and Camelina sativa oil on atherogenic and anti-atherogenic functions of LDL and HDL particles: A randomized controlled trial

Neutrophil proteinase 3 — An LDL- and HDL-proteolyzing enzyme with a potential to contribute to cholesterol accumulation in human atherosclerotic lesions

The human liver lipidome is significantly related to the lipid composition and aggregation susceptibility of low-density lipoprotein (LDL) particles

Cathepsin G activity lowers plasma LDL and reduces atherosclerosis

Vasculoprotective properties of plasma lipoproteins from brown bears (Ursus arctos)

Low-density lipoprotein aggregation predicts adverse cardiovascular events in peripheral artery disease

The year 2020 in Atherosclerosis

Modified lipoprotein-derived lipid particles accumulate in human stenotic aortic valves

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