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Enzymatic Neutralization of the Chemical Warfare Agent VX: Evolution of Phosphotriesterase for Phosphorothiolate Hydrolysis

Journal of the American Chemical Society, 2013-07, Vol.135 (28), p.10426-10432

2013

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Chemical Mechanism of the Phosphotriesterase from Sphingobium sp. Strain TCM1, an Enzyme Capable of Hydrolyzing Organophosphate Flame Retardants

Journal of the American Chemical Society, 2016-03, Vol.138 (9), p.2921-2924

2016

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Substrate Distortion and the Catalytic Reaction Mechanism of 5‑Carboxyvanillate Decarboxylase

Journal of the American Chemical Society, 2016-01, Vol.138 (3), p.826-836

2016

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Enhanced Degradation of Chemical Warfare Agents through Molecular Engineering of the Phosphotriesterase Active Site

Journal of the American Chemical Society, 2003-07, Vol.125 (30), p.8990-8991

2003

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Enzymatic Deamination of the Epigenetic Base N-6-Methyladenine

Journal of the American Chemical Society, 2011-02, Vol.133 (7), p.2080-2083

2011

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Discovery of a Glutamine Kinase Required for the Biosynthesis of the O‑Methyl Phosphoramidate Modifications Found in the Capsular Polysaccharides of Campylobacter jejuni

Journal of the American Chemical Society, 2017-07, Vol.139 (28), p.9463-9466

2017

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Tight Binding Inhibitors of N-Acyl Amino Sugar and N-Acyl Amino Acid Deacetylases

Journal of the American Chemical Society, 2006-04, Vol.128 (13), p.4244-4245

2006

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Enzymatic Resolution of Chiral Phosphinate Esters

Journal of the American Chemical Society, 2004-07, Vol.126 (29), p.8888-8889

2004

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Molecular Engineering of Organophosphate Hydrolysis Activity from a Weak Promiscuous Lactonase Template

Journal of the American Chemical Society, 2013-08, Vol.135 (31), p.11670-11677

2013

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Discovery of a Cyclic Phosphodiesterase That Catalyzes the Sequential Hydrolysis of Both Ester Bonds to Phosphorus

Journal of the American Chemical Society, 2013-11, Vol.135 (44), p.16360-16363

2013

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Substrate Deconstruction and the Nonadditivity of Enzyme Recognition

Journal of the American Chemical Society, 2014-05, Vol.136 (20), p.7374-7382

2014

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Predicting Substrates by Docking High-Energy Intermediates to Enzyme Structures

Journal of the American Chemical Society, 2006-12, Vol.128 (49), p.15882-15891

2006

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Structure-Guided Discovery of New Deaminase Enzymes

Journal of the American Chemical Society, 2013-09, Vol.135 (37), p.13927-13933

2013

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Operational Control of Stereoselectivity during the Enzymatic Hydrolysis of Racemic Organophosphorus Compounds

Journal of the American Chemical Society, 2003-06, Vol.125 (25), p.7526-7527

2003

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Assignment of Pterin Deaminase Activity to an Enzyme of Unknown Function Guided by Homology Modeling and Docking

Journal of the American Chemical Society, 2013-01, Vol.135 (2), p.795-803

2013

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A Combined Theoretical and Experimental Study of the Ammonia Tunnel in Carbamoyl Phosphate Synthetase

Journal of the American Chemical Society, 2009-07, Vol.131 (29), p.10211-10219

2009

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Carbamate Transport in Carbamoyl Phosphate Synthetase: A Theoretical and Experimental Investigation

Journal of the American Chemical Society, 2010-03, Vol.132 (11), p.3870-3878

2010

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Substrate Distortion and the Catalytic Reaction Mechanism of 5-Carboxyvanillate Decarboxylase

Journal of the American Chemical Society, 2016-01, Vol.138 (3)

2016

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Resolution of Chiral Phosphate, Phosphonate, and Phosphinate Esters by an Enantioselective Enzyme Library

Journal of the American Chemical Society, 2006-12, Vol.128 (49), p.15892-15902

2006

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Channeling of Ammonia through the Intermolecular Tunnel Contained within Carbamoyl Phosphate Synthetase

Journal of the American Chemical Society, 1999-04, Vol.121 (15), p.3803-3804

1999

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Enzymatic Synthesis of Chiral Organophosphothioates from Prochiral Precursors

Journal of the American Chemical Society, 2002-04, Vol.124 (14), p.3498-3499

2002

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The Hunt for 8-Oxoguanine Deaminase

Journal of the American Chemical Society, 2010-02, Vol.132 (6), p.1762-1763

2010

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Hydrolysis of Phosphotriesters: Determination of Transition States in Parallel Reactions by Heavy-Atom Isotope Effects

Journal of the American Chemical Society, 2001-09, Vol.123 (38), p.9246-9253

2001

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The Multiple Amidation Reactions Catalyzed by Cobyric Acid Synthetase from Salmonella typhimurium Are Sequential and Dissociative

Journal of the American Chemical Society, 2007-01, Vol.129 (2), p.294-295

2007

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Rationally Engineered Mutants of Phosphotriesterase for Preparative Scale Isolation of Chiral Organophosphates

Journal of the American Chemical Society, 2000-10, Vol.122 (41), p.10206-10207

2000

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Enzymatic Neutralization of the Chemical Warfare Agent VX: Evolution of Phosphotriesterase for Phosphorothiolate Hydrolysis

Chemical Mechanism of the Phosphotriesterase from Sphingobium sp. Strain TCM1, an Enzyme Capable of Hydrolyzing Organophosphate Flame Retardants

Substrate Distortion and the Catalytic Reaction Mechanism of 5‑Carboxyvanillate Decarboxylase

Enhanced Degradation of Chemical Warfare Agents through Molecular Engineering of the Phosphotriesterase Active Site

Enzymatic Deamination of the Epigenetic Base N-6-Methyladenine

Discovery of a Glutamine Kinase Required for the Biosynthesis of the O‑Methyl Phosphoramidate Modifications Found in the Capsular Polysaccharides of Campylobacter jejuni

Tight Binding Inhibitors of N-Acyl Amino Sugar and N-Acyl Amino Acid Deacetylases

Enzymatic Resolution of Chiral Phosphinate Esters

Molecular Engineering of Organophosphate Hydrolysis Activity from a Weak Promiscuous Lactonase Template

Discovery of a Cyclic Phosphodiesterase That Catalyzes the Sequential Hydrolysis of Both Ester Bonds to Phosphorus

Substrate Deconstruction and the Nonadditivity of Enzyme Recognition

Predicting Substrates by Docking High-Energy Intermediates to Enzyme Structures

Structure-Guided Discovery of New Deaminase Enzymes

Operational Control of Stereoselectivity during the Enzymatic Hydrolysis of Racemic Organophosphorus Compounds

Assignment of Pterin Deaminase Activity to an Enzyme of Unknown Function Guided by Homology Modeling and Docking

A Combined Theoretical and Experimental Study of the Ammonia Tunnel in Carbamoyl Phosphate Synthetase

Carbamate Transport in Carbamoyl Phosphate Synthetase: A Theoretical and Experimental Investigation

Substrate Distortion and the Catalytic Reaction Mechanism of 5-Carboxyvanillate Decarboxylase

Resolution of Chiral Phosphate, Phosphonate, and Phosphinate Esters by an Enantioselective Enzyme Library

Channeling of Ammonia through the Intermolecular Tunnel Contained within Carbamoyl Phosphate Synthetase

Enzymatic Synthesis of Chiral Organophosphothioates from Prochiral Precursors

The Hunt for 8-Oxoguanine Deaminase

Hydrolysis of Phosphotriesters: Determination of Transition States in Parallel Reactions by Heavy-Atom Isotope Effects

The Multiple Amidation Reactions Catalyzed by Cobyric Acid Synthetase from Salmonella typhimurium Are Sequential and Dissociative

Rationally Engineered Mutants of Phosphotriesterase for Preparative Scale Isolation of Chiral Organophosphates

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