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PIK3CA mutations in breast cancer: reconciling findings from preclinical and clinical data

Breast cancer research : BCR, 2014-01, Vol.16 (1), p.201-201, Article 201

2014

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Inhibiting the system xC−/glutathione axis selectively targets cancers with mutant-p53 accumulation

Nature communications, 2017-03, Vol.8 (1), p.14844-14844, Article 14844

2017

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Activating BRAF and PIK3CA mutations cooperate to promote anaplastic thyroid carcinogenesis

Molecular cancer research, 2014-07, Vol.12 (7), p.979-986

2014

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A central role for RAF→MEK→ERK signaling in the genesis of pancreatic ductal adenocarcinoma

Cancer discovery, 2012-08, Vol.2 (8), p.685-693

2012

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Oncogenic PIK3CA induces centrosome amplification and tolerance to genome doubling

Nature communications, 2017-11, Vol.8 (1), p.1773-15, Article 1773

2017

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PIK3CA mutations associated with gene signature of low mTORC1 signaling and better outcomes in estrogen receptor—positive breast cancer

Proceedings of the National Academy of Sciences - PNAS, 2010-06, Vol.107 (22), p.10208-10213

2010

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Molecular biology of anal squamous cell carcinoma: implications for future research and clinical intervention

The lancet oncology, 2015-12, Vol.16 (16), p.e611-e621

2015

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YBX1 integration of oncogenic PI3K/mTOR signalling regulates the fitness of malignant epithelial cells

Nature communications, 2023-03, Vol.14 (1), p.1591-1591, Article 1591

2023

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Transketolase regulates sensitivity to APR-246 in p53-null cells independently of oxidative stress modulation

Scientific reports, 2021-02, Vol.11 (1), p.4480-4480, Article 4480

2021

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Mutation of the PIK3CA gene in ovarian and breast cancer

Cancer research (Chicago, Ill.), 2004-11, Vol.64 (21), p.7678-7681

2004

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Signaling pathways in the molecular pathogenesis of adenocarcinomas of the esophagus and gastroesophageal junction

Cancer biology & therapy, 2013-09, Vol.14 (9), p.782-795

2013

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Synergistic inhibition of ovarian cancer cell growth by combining selective PI3K/mTOR and RAS/ERK pathway inhibitors

European journal of cancer (1990), 2013-12, Vol.49 (18), p.3936-3944

2013

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Caspase-2 protects against ferroptotic cell death

Cell death & disease, 2024-03, Vol.15 (3), p.182-182

2024

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Aberrant Epithelial–Mesenchymal Hedgehog Signaling Characterizes Barrett's Metaplasia

Gastroenterology (New York, N.Y. 1943), 2010-05, Vol.138 (5), p.1810-1822.e2

2010

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Copper as a target for prostate cancer therapeutics: copper-ionophore pharmacology and altering systemic copper distribution

Oncotarget, 2016-06, Vol.7 (24), p.37064-37080

2016

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Mouse Models for Exploring the Biological Consequences and Clinical Significance of PIK3CA Mutations

Biomolecules (Basel, Switzerland), 2019-04, Vol.9 (4), p.158

2019

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Physiological levels of Pik3ca(H1047R) mutation in the mouse mammary gland results in ductal hyperplasia and formation of ERα-positive tumors

PloS one, 2012, Vol.7 (5), p.e36924-e36924

2012

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Combined MEK and Pi3'-kinase inhibition reveals synergy in targeting thyroid cancer in vitro and in vivo

Oncotarget, 2017-04, Vol.8 (15), p.24604-24620

2017

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Sox9 drives columnar differentiation of esophageal squamous epithelium: a possible role in the pathogenesis of Barrett's esophagus

American journal of physiology: Gastrointestinal and liver physiology, 2012-12, Vol.303 (12), p.G1335-G1346

2012

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Molecular and genomic characterisation of a panel of human anal cancer cell lines

Cell death & disease, 2021-10, Vol.12 (11), p.959-15, Article 959

2021

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Identification of Candidate Murine Esophageal Stem Cells Using a Combination of Cell Kinetic Studies and Cell Surface Markers

Stem cells (Dayton, Ohio), 2007-02, Vol.25 (2), p.313-318

2007

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PIK3CA mutations are specifically localized to lymphatic endothelial cells of lymphatic malformations

PloS one, 2018-07, Vol.13 (7), p.e0200343-e0200343

2018

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Reactivation of multipotency by oncogenic PIK3CA induces breast tumour heterogeneity

Nature (London), 2015-09, Vol.525 (7567), p.119-123

2015

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Pretreatment Transcriptional Profiling for Predicting Response to Neoadjuvant Chemoradiotherapy in Rectal Adenocarcinoma

Clinical cancer research, 2011-05, Vol.17 (9), p.3039-3047

2011

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PIK3CA mutations in breast cancer: reconciling findings from preclinical and clinical data

Inhibiting the system xC−/glutathione axis selectively targets cancers with mutant-p53 accumulation

Activating BRAF and PIK3CA mutations cooperate to promote anaplastic thyroid carcinogenesis

A central role for RAF→MEK→ERK signaling in the genesis of pancreatic ductal adenocarcinoma

Oncogenic PIK3CA induces centrosome amplification and tolerance to genome doubling

PIK3CA mutations associated with gene signature of low mTORC1 signaling and better outcomes in estrogen receptor—positive breast cancer

Molecular biology of anal squamous cell carcinoma: implications for future research and clinical intervention

YBX1 integration of oncogenic PI3K/mTOR signalling regulates the fitness of malignant epithelial cells

Transketolase regulates sensitivity to APR-246 in p53-null cells independently of oxidative stress modulation

Mutation of the PIK3CA gene in ovarian and breast cancer

Signaling pathways in the molecular pathogenesis of adenocarcinomas of the esophagus and gastroesophageal junction

Synergistic inhibition of ovarian cancer cell growth by combining selective PI3K/mTOR and RAS/ERK pathway inhibitors

Caspase-2 protects against ferroptotic cell death

Aberrant Epithelial–Mesenchymal Hedgehog Signaling Characterizes Barrett's Metaplasia

Copper as a target for prostate cancer therapeutics: copper-ionophore pharmacology and altering systemic copper distribution

Mouse Models for Exploring the Biological Consequences and Clinical Significance of PIK3CA Mutations

Identification of the CIMP-like subtype and aberrant methylation of members of the chromosomal segregation and spindle assembly pathways in esophageal adenocarcinoma

Physiological levels of Pik3ca(H1047R) mutation in the mouse mammary gland results in ductal hyperplasia and formation of ERα-positive tumors

Combined MEK and Pi3'-kinase inhibition reveals synergy in targeting thyroid cancer in vitro and in vivo

Sox9 drives columnar differentiation of esophageal squamous epithelium: a possible role in the pathogenesis of Barrett's esophagus

Molecular and genomic characterisation of a panel of human anal cancer cell lines

Identification of Candidate Murine Esophageal Stem Cells Using a Combination of Cell Kinetic Studies and Cell Surface Markers

PIK3CA mutations are specifically localized to lymphatic endothelial cells of lymphatic malformations

Reactivation of multipotency by oncogenic PIK3CA induces breast tumour heterogeneity

Pretreatment Transcriptional Profiling for Predicting Response to Neoadjuvant Chemoradiotherapy in Rectal Adenocarcinoma

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