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Adaptive mutability of colorectal cancers in response to targeted therapies

Science (American Association for the Advancement of Science), 2019-12, Vol.366 (6472), p.1473-1480

2019

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ARID1A deficiency promotes mutability and potentiates therapeutic antitumor immunity unleashed by immune checkpoint blockade

Nature medicine, 2018-05, Vol.24 (5), p.556-562

2018

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Human Variation in DNA Repair, Immune Function, and Cancer Risk

Frontiers in immunology, 2022-07, Vol.13, p.899574

2022

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DNA Repair Capacity in Multiple Pathways Predicts Chemoresistance in Glioblastoma Multiforme

Cancer research (Chicago, Ill.), 2017-01, Vol.77 (1), p.198-206

2017

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Update 1 of: Tunneling and Dynamics in Enzymatic Hydride Transfer

Chemical reviews, 2010-12, Vol.110 (12), p.PR41-PR67

2010

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ATM phosphorylates the FATC domain of DNA-PKcs at threonine 4102 to promote non-homologous end joining

Nucleic acids research, 2023-07, Vol.51 (13), p.6770-6783

2023

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Selective small molecule PARG inhibitor causes replication fork stalling and cancer cell death

Nature communications, 2019-12, Vol.10 (1), p.5654-15, Article 5654

2019

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Cosmic Ionizing Radiation: A DNA Damaging Agent That May Underly Excess Cancer in Flight Crews

International journal of molecular sciences, 2024-07, Vol.25 (14), p.7670

2024

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Base excision repair and double strand break repair cooperate to modulate the formation of unrepaired double strand breaks in mouse brain

Nature communications, 2024-09, Vol.15 (1), p.7726-18, Article 7726

2024

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Defective base excision repair in the response to DNA damaging agents in triple negative breast cancer

PloS one, 2019-10, Vol.14 (10), p.e0223725-e0223725

2019

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In vivo measurements of interindividual differences in DNA glycosylases and APE1 activities

Proceedings of the National Academy of Sciences - PNAS, 2017-11, Vol.114 (48), p.E10379-E10388

2017

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Multiplexed DNA repair assays for multiple lesions and multiple doses via transcription inhibition and transcriptional mutagenesis

Proceedings of the National Academy of Sciences - PNAS, 2014-05, Vol.111 (18), p.6540-6540

2014

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CometChip analysis of human primary lymphocytes enables quantification of inter-individual differences in the kinetics of repair of oxidative DNA damage

Free radical biology & medicine, 2021-10, Vol.174, p.89-99

2021

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ATM inhibition exploits checkpoint defects and ATM-dependent double strand break repair in TP53-mutant glioblastoma

Nature communications, 2024-06, Vol.15 (1), p.5294-22, Article 5294

2024

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The CHD6 chromatin remodeler is an oxidative DNA damage response factor

Nature communications, 2019-01, Vol.10 (1), p.241-241, Article 241

2019

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REV7 Monomer Is Unable to Participate in Double Strand Break Repair and Translesion Synthesis but Suppresses Mitotic Errors

International journal of molecular sciences, 2023-11, Vol.24 (21), p.15799

2023

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Fluorescent reporter assays provide direct, accurate, quantitative measurements of MGMT status in human cells

PloS one, 2019-02, Vol.14 (2), p.e0208341

2019

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EZH2 has a non-catalytic and PRC2-independent role in stabilizing DDB2 to promote nucleotide excision repair

Oncogene, 2020-06, Vol.39 (25), p.4798-4813

2020

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Cancer risks from cosmic radiation exposure in flight: A review

Frontiers in public health, 2022-11, Vol.10, p.947068

2022

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Fluorogenic Real-Time Reporters of DNA Repair by MGMT, a Clinical Predictor of Antitumor Drug Response

PloS one, 2016-04, Vol.11 (4), p.e0152684-e0152684

2016

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Impaired protein conformational landscapes as revealed in anomalous Arrhenius prefactors

Proceedings of the National Academy of Sciences - PNAS, 2011-06, Vol.108 (26), p.10520-10525

2011

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Exploiting DNA repair defects in triple negative breast cancer to improve cell killing

Therapeutic advances in medical oncology, 2020, Vol.12, p.1758835920958354-1758835920958354

2020

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Sodium sulfide selectively induces oxidative stress, DNA damage, and mitochondrial dysfunction and radiosensitizes glioblastoma (GBM) cells

Redox biology, 2019-09, Vol.26, p.101220-101220, Article 101220

2019

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Active Site Hydrophobic Residues Impact Hydrogen Tunneling Differently in a Thermophilic Alcohol Dehydrogenase at Optimal versus Nonoptimal Temperatures

Biochemistry (Easton), 2012-05, Vol.51 (20), p.4147-4156

2012

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Interplay Between Air Travel, Genome Integrity, and COVID-19 Risk vis-a-vis Flight Crew

Frontiers in public health, 2020-12, Vol.8, p.590412

2020

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Adaptive mutability of colorectal cancers in response to targeted therapies

ARID1A deficiency promotes mutability and potentiates therapeutic antitumor immunity unleashed by immune checkpoint blockade

Human Variation in DNA Repair, Immune Function, and Cancer Risk

DNA Repair Capacity in Multiple Pathways Predicts Chemoresistance in Glioblastoma Multiforme

Update 1 of: Tunneling and Dynamics in Enzymatic Hydride Transfer

ATM phosphorylates the FATC domain of DNA-PKcs at threonine 4102 to promote non-homologous end joining

Selective small molecule PARG inhibitor causes replication fork stalling and cancer cell death

Cosmic Ionizing Radiation: A DNA Damaging Agent That May Underly Excess Cancer in Flight Crews

Base excision repair and double strand break repair cooperate to modulate the formation of unrepaired double strand breaks in mouse brain

Defective base excision repair in the response to DNA damaging agents in triple negative breast cancer

In vivo measurements of interindividual differences in DNA glycosylases and APE1 activities

Multiplexed DNA repair assays for multiple lesions and multiple doses via transcription inhibition and transcriptional mutagenesis

CometChip analysis of human primary lymphocytes enables quantification of inter-individual differences in the kinetics of repair of oxidative DNA damage

ATM inhibition exploits checkpoint defects and ATM-dependent double strand break repair in TP53-mutant glioblastoma

The CHD6 chromatin remodeler is an oxidative DNA damage response factor

REV7 Monomer Is Unable to Participate in Double Strand Break Repair and Translesion Synthesis but Suppresses Mitotic Errors

Fluorescent reporter assays provide direct, accurate, quantitative measurements of MGMT status in human cells

EZH2 has a non-catalytic and PRC2-independent role in stabilizing DDB2 to promote nucleotide excision repair

Cancer risks from cosmic radiation exposure in flight: A review

Fluorogenic Real-Time Reporters of DNA Repair by MGMT, a Clinical Predictor of Antitumor Drug Response

Impaired protein conformational landscapes as revealed in anomalous Arrhenius prefactors

Exploiting DNA repair defects in triple negative breast cancer to improve cell killing

Sodium sulfide selectively induces oxidative stress, DNA damage, and mitochondrial dysfunction and radiosensitizes glioblastoma (GBM) cells

Active Site Hydrophobic Residues Impact Hydrogen Tunneling Differently in a Thermophilic Alcohol Dehydrogenase at Optimal versus Nonoptimal Temperatures

Interplay Between Air Travel, Genome Integrity, and COVID-19 Risk vis-a-vis Flight Crew

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