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Is the oral route possible for peptide and protein drug delivery?

Drug discovery today, 2006-10, Vol.11 (19), p.905-910

2006

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The Expert of the Medicine Explains “Understanding of the Novel Coronavirus Vaccine”

YAKUGAKU ZASSHI, 2022/06/01, Vol.142(6), pp.597-599

2022

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Mechanistic Study of the Uptake/Permeation of Cell-Penetrating Peptides Across a Caco-2 Monolayer and Their Stimulatory Effect on Epithelial Insulin Transport

Journal of pharmaceutical sciences, 2013-11, Vol.102 (11), p.3998-4008

2013

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In Vivo Proof of Biological Safety and Physiological Effects of Orally Ingested Water Containing H2-Filled Ultrafine Bubbles (UFBs)

Biological and Pharmaceutical Bulletin, 2023/02/01, Vol.46(2), pp.343-347

2023

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Importance of intermolecular interaction on the improvement of intestinal therapeutic peptide/protein absorption using cell-penetrating peptides

Journal of controlled release, 2009-06, Vol.136 (3), p.179-186

2009

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Evaluation of Bactericidal Effects of H2- and O3-filled Ultrafine Bubbles Water

Biocontrol Science, 2022, Vol.27(3), pp.139-142

2022

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Noncovalent Strategy with Cell-Penetrating Peptides to Facilitate the Brain Delivery of Insulin through the Blood–Brain Barrier

Biological and Pharmaceutical Bulletin, 2018/04/01, Vol.41(4), pp.546-554

2018

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Combination Strategy with Complexation Hydrogels and Cell-Penetrating Peptides for Oral Delivery of Insulin

Biological and Pharmaceutical Bulletin, 2018/05/01, Vol.41(5), pp.811-814

2018

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Pharmacokinetic interaction study of sulphasalazine in healthy subjects and the impact of curcumin as an in vivo inhibitor of BCRP

British journal of pharmacology, 2012-07, Vol.166 (6), p.1793-1803

2012

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A novel approach using functional peptides for efficient intestinal absorption of insulin

Journal of controlled release, 2007-04, Vol.118 (2), p.177-184

2007

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Exploration of the Key Factors for Optimizing the in Vivo Oral Delivery of Insulin by Using a Noncovalent Strategy with Cell-Penetrating Peptides

Biological and Pharmaceutical Bulletin, 2018/02/01, Vol.41(2), pp.239-246

2018

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Safety of the Cell-Penetrating Peptide Penetratin as an Oral Absorption Enhancer

Biological and Pharmaceutical Bulletin, 2015/01/01, Vol.38(1), pp.144-146

2015

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Evaluation of Cell-Penetrating Peptides as Versatile, Effective Absorption Enhancers: Relation to Molecular Weight and Inherent Epithelial Drug Permeability

Pharmaceutical research, 2020-10, Vol.37 (10), p.182-182, Article 182

2020

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Effect of cell-penetrating peptides on the nasal absorption of insulin

Journal of controlled release, 2009-01, Vol.133 (2), p.103-108

2009

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Determination of the Optimal Cell-Penetrating Peptide Sequence for Intestinal Insulin Delivery Based on Molecular Orbital Analysis with Self-Organizing Maps

Journal of pharmaceutical sciences, 2013-02, Vol.102 (2), p.469-479

2013

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Molecular imaging analysis of intestinal insulin absorption boosted by cell-penetrating peptides by using positron emission tomography

Journal of controlled release, 2010-08, Vol.146 (1), p.16-22

2010

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Carboxymethylation of kappa-carrageenan for intestinal-targeted delivery of bioactive macromolecules

Carbohydrate polymers, 2011-02, Vol.83 (4), p.1507-1515

2011

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Permeation characteristics of oligoarginine through intestinal epithelium and its usefulness for intestinal peptide drug delivery

Journal of controlled release, 2008-10, Vol.131 (2), p.94-99

2008

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Effect of excipients on breast cancer resistance protein substrate uptake activity

Journal of controlled release, 2007-12, Vol.124 (1), p.1-5

2007

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Efficiency of cell-penetrating peptides on the nasal and intestinal absorption of therapeutic peptides and proteins

International journal of pharmaceutics, 2009-10, Vol.381 (1), p.49-55

2009

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Patient experience (PX) among individuals with disabilities in Japan: a mixed-methods study

BMC primary care, 2022-07, Vol.23 (1), p.183-183, Article 183

2022

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The Effects of Andrographolide on the Enhancement of Chondrogenesis and Osteogenesis in Human Suprapatellar Fat Pad Derived Mesenchymal Stem Cells

Molecules (Basel, Switzerland), 2021-03, Vol.26 (7), p.1831

2021

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Potential of single cationic amino acid molecule “Arginine” for stimulating oral absorption of insulin

International journal of pharmaceutics, 2017-04, Vol.521 (1-2), p.176-183

2017

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Effects of Cremophor EL on the absorption of orally administered saquinavir and fexofenadine in healthy subjects

Drug metabolism and pharmacokinetics, 2015-06, Vol.30 (3), p.221-226

2015

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Improvement of the oral drug absorption of topotecan through the inhibition of intestinal xenobiotic efflux transporter, breast cancer resistance protein, by excipients

Drug metabolism and disposition, 2007-07, Vol.35 (7), p.1142

2007

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Is the oral route possible for peptide and protein drug delivery?

The Expert of the Medicine Explains “Understanding of the Novel Coronavirus Vaccine”

Mechanistic Study of the Uptake/Permeation of Cell-Penetrating Peptides Across a Caco-2 Monolayer and Their Stimulatory Effect on Epithelial Insulin Transport

In Vivo Proof of Biological Safety and Physiological Effects of Orally Ingested Water Containing H2-Filled Ultrafine Bubbles (UFBs)

Importance of intermolecular interaction on the improvement of intestinal therapeutic peptide/protein absorption using cell-penetrating peptides

Evaluation of Bactericidal Effects of H2- and O3-filled Ultrafine Bubbles Water

Noncovalent Strategy with Cell-Penetrating Peptides to Facilitate the Brain Delivery of Insulin through the Blood–Brain Barrier

Combination Strategy with Complexation Hydrogels and Cell-Penetrating Peptides for Oral Delivery of Insulin

Pharmacokinetic interaction study of sulphasalazine in healthy subjects and the impact of curcumin as an in vivo inhibitor of BCRP

A novel approach using functional peptides for efficient intestinal absorption of insulin

Exploration of the Key Factors for Optimizing the in Vivo Oral Delivery of Insulin by Using a Noncovalent Strategy with Cell-Penetrating Peptides

Safety of the Cell-Penetrating Peptide Penetratin as an Oral Absorption Enhancer

Evaluation of Cell-Penetrating Peptides as Versatile, Effective Absorption Enhancers: Relation to Molecular Weight and Inherent Epithelial Drug Permeability

Effect of cell-penetrating peptides on the nasal absorption of insulin

Determination of the Optimal Cell-Penetrating Peptide Sequence for Intestinal Insulin Delivery Based on Molecular Orbital Analysis with Self-Organizing Maps

Molecular imaging analysis of intestinal insulin absorption boosted by cell-penetrating peptides by using positron emission tomography

Carboxymethylation of kappa-carrageenan for intestinal-targeted delivery of bioactive macromolecules

Permeation characteristics of oligoarginine through intestinal epithelium and its usefulness for intestinal peptide drug delivery

Effect of excipients on breast cancer resistance protein substrate uptake activity

Efficiency of cell-penetrating peptides on the nasal and intestinal absorption of therapeutic peptides and proteins

Patient experience (PX) among individuals with disabilities in Japan: a mixed-methods study

The Effects of Andrographolide on the Enhancement of Chondrogenesis and Osteogenesis in Human Suprapatellar Fat Pad Derived Mesenchymal Stem Cells

Potential of single cationic amino acid molecule “Arginine” for stimulating oral absorption of insulin

Effects of Cremophor EL on the absorption of orally administered saquinavir and fexofenadine in healthy subjects

Improvement of the oral drug absorption of topotecan through the inhibition of intestinal xenobiotic efflux transporter, breast cancer resistance protein, by excipients

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