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Effects of Additive Tolvaptan vs. Increased Furosemide on Heart Failure With Diuretic Resistance and Renal Impairment　― Results From the K-STAR Study

Circulation Journal, 2017/12/25, Vol.82(1), pp.159-167

2018

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Concentration-QTc analysis with two or more correlated baselines

Journal of pharmacokinetics and pharmacodynamics, 2021-10, Vol.48 (5), p.615-622

2021

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Plasma and serum lipidomics of healthy white adults shows characteristic profiles by subjects' gender and age

PloS one, 2014-03, Vol.9 (3), p.e91806-e91806

2014

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Investigation of Endogenous Compounds Applicable to Drug-Drug Interaction Studies Involving the Renal Organic Anion Transporters, OAT1 and OAT3, in Humans

Drug metabolism and disposition, 2016-12, Vol.44 (12), p.1925-1933

2016

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Appraisal of ICH E14/S7B Q&As adopted in February 2022 using thorough QT/QTc study data for α4-integrin antagonist carotegrast methyl in Japanese healthy subjects

Journal of pharmacological sciences, 2022-11, Vol.150 (3), p.191-199

2022

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Effect of single and multiple doses of elobixibat, an ileal bile acid transporter inhibitor, on chronic constipation: A randomized controlled trial

British journal of clinical pharmacology, 2018-10, Vol.84 (10), p.2393-2404

2018

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Ferric citrate hydrate for the treatment of hyperphosphatemia in nondialysis-dependent CKD

Clinical journal of the American Society of Nephrology, 2014-03, Vol.9 (3), p.543-552

2014

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Concentration–QTc analysis for single arm studies

Journal of pharmacokinetics and pharmacodynamics, 2021-04, Vol.48 (2), p.203-211

2021

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Gender- and Age-Associated Differences in Serum Metabolite Profiles among Japanese Populations

Biological and Pharmaceutical Bulletin, 2016/07/01, Vol.39(7), pp.1179-1186

2016

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A drug–drug interaction study of a novel, selective urate reabsorption inhibitor dotinurad and the non-steroidal anti-inflammatory drug oxaprozin in healthy adult males

Clinical and experimental nephrology, 2020-03, Vol.24 (Suppl 1), p.36-43

2020

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Inhibitory effects of p-aminohippurate and probenecid on the renal clearance of adefovir and benzylpenicillin as probe drugs for organic anion transporter (OAT) 1 and OAT3 in humans

European journal of pharmaceutical sciences, 2014-08, Vol.59, p.94-103

2014

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The intercellular expression of type-XVII collagen, laminin-332, and integrin-β1 promote contact following during the collective invasion of a cancer cell population

Biochemical and biophysical research communications, 2019-07, Vol.514 (4), p.1115-1121

2019

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Safety, Tolerability, and Pharmacokinetics of Belumosudil, a Selective Rho-associated Coiled-coil-containing Protein Kinase 2 Inhibitor, in Healthy Japanese Volunteers: A PhaseⅠ, Randomized, Controlled Trial

Rinshō yakuri, 2023-09, Vol.54 (5), p.197-203

2023

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Pharmacokinetics, Pharmacodynamics, and Safety of E6011, a Novel Humanized Antifractalkine (CX3CL1) Monoclonal Antibody: A Randomized, Double‐Blind, Placebo‐Controlled Single‐Ascending‐Dose Study

Journal of clinical pharmacology, 2019-05, Vol.59 (5), p.688-701

2019

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Mammaglobin 1 mediates progression of trastuzumab‐resistant breast cancer cells through regulation of cyclins and NF‐κB

FEBS open bio, 2022-10, Vol.12 (10), p.1797-1813

2022

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Plasma Lipidomics of Healthy Japanese Adults Reveals Gender- and Age-Related Differences

Journal of pharmaceutical sciences, 2017-09, Vol.106 (9), p.2914-2918

2017

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The interferon-β/STAT1 axis drives the collective invasion of skin squamous cell carcinoma with sealed intercellular spaces

Oncogenesis (New York, NY), 2022-05, Vol.11 (1), p.27-27, Article 27

2022

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Effects of zolpidem/triazolam on cognitive performance 12 hours after acute administration

Sleep medicine, 2018-12, Vol.52, p.213-218

2018

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Effect of Oral JTT-751 (Ferric Citrate) on Hyperphosphatemia in Hemodialysis Patients: Results of a Randomized, Double-Blind, Placebo-Controlled Trial

American journal of nephrology, 2012-01, Vol.36 (5), p.478-487

2012

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A randomized, double-blind, placebo-controlled, single-dose study to evaluate the safety, tolerability, pharmacokinetics and pharmacodynamics of denosumab administered subcutaneously to postmenopausal Japanese women

Bone (New York, N.Y.), 2011-11, Vol.49 (5), p.1101-1107

2011

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Investigation of Endogenous Compounds for Assessing the Drug Interactions in the Urinary Excretion Involving Multidrug and Toxin Extrusion Proteins

Pharmaceutical research, 2014-01, Vol.31 (1), p.136-147

2014

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Randomized, Controlled, Thorough QT/QTc Study Shows Absence of QT Prolongation with Luseogliflozin in Healthy Japanese Subjects

PloS one, 2015-10, Vol.10 (10), p.e0139873-e0139873

2015

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Strategy to avoid local recurrence in patients with locally advanced rectal cancer

Radiation oncology (London, England), 2019-03, Vol.14 (1), p.53-53, Article 53

2019

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Research on Information Used in the Development of Pediatric Drugs in Japan: Utilization of Pharmacokinetic Information

Rinshō yakuri, 2024-01, Vol.55 (1), p.3-10

2024

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Long-Term Safety and Efficacy of a Novel Iron-Containing Phosphate Binder, JTT-751, in Patients Receiving Hemodialysis

Journal of renal nutrition, 2014-07, Vol.24 (4), p.261-267

2014

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Effects of Additive Tolvaptan vs. Increased Furosemide on Heart Failure With Diuretic Resistance and Renal Impairment　― Results From the K-STAR Study

Concentration-QTc analysis with two or more correlated baselines

Plasma and serum lipidomics of healthy white adults shows characteristic profiles by subjects' gender and age

Investigation of Endogenous Compounds Applicable to Drug-Drug Interaction Studies Involving the Renal Organic Anion Transporters, OAT1 and OAT3, in Humans

Appraisal of ICH E14/S7B Q&As adopted in February 2022 using thorough QT/QTc study data for α4-integrin antagonist carotegrast methyl in Japanese healthy subjects

Effect of single and multiple doses of elobixibat, an ileal bile acid transporter inhibitor, on chronic constipation: A randomized controlled trial

Ferric citrate hydrate for the treatment of hyperphosphatemia in nondialysis-dependent CKD

Concentration–QTc analysis for single arm studies

Gender- and Age-Associated Differences in Serum Metabolite Profiles among Japanese Populations

A drug–drug interaction study of a novel, selective urate reabsorption inhibitor dotinurad and the non-steroidal anti-inflammatory drug oxaprozin in healthy adult males

Inhibitory effects of p-aminohippurate and probenecid on the renal clearance of adefovir and benzylpenicillin as probe drugs for organic anion transporter (OAT) 1 and OAT3 in humans

The intercellular expression of type-XVII collagen, laminin-332, and integrin-β1 promote contact following during the collective invasion of a cancer cell population

Safety, Tolerability, and Pharmacokinetics of Belumosudil, a Selective Rho-associated Coiled-coil-containing Protein Kinase 2 Inhibitor, in Healthy Japanese Volunteers: A PhaseⅠ, Randomized, Controlled Trial

Pharmacokinetics, Pharmacodynamics, and Safety of E6011, a Novel Humanized Antifractalkine (CX3CL1) Monoclonal Antibody: A Randomized, Double‐Blind, Placebo‐Controlled Single‐Ascending‐Dose Study

Mammaglobin 1 mediates progression of trastuzumab‐resistant breast cancer cells through regulation of cyclins and NF‐κB

Plasma Lipidomics of Healthy Japanese Adults Reveals Gender- and Age-Related Differences

The interferon-β/STAT1 axis drives the collective invasion of skin squamous cell carcinoma with sealed intercellular spaces

Effects of zolpidem/triazolam on cognitive performance 12 hours after acute administration

Effect of Oral JTT-751 (Ferric Citrate) on Hyperphosphatemia in Hemodialysis Patients: Results of a Randomized, Double-Blind, Placebo-Controlled Trial

A randomized, double-blind, placebo-controlled, single-dose study to evaluate the safety, tolerability, pharmacokinetics and pharmacodynamics of denosumab administered subcutaneously to postmenopausal Japanese women

Investigation of Endogenous Compounds for Assessing the Drug Interactions in the Urinary Excretion Involving Multidrug and Toxin Extrusion Proteins

Randomized, Controlled, Thorough QT/QTc Study Shows Absence of QT Prolongation with Luseogliflozin in Healthy Japanese Subjects

Strategy to avoid local recurrence in patients with locally advanced rectal cancer

Research on Information Used in the Development of Pediatric Drugs in Japan: Utilization of Pharmacokinetic Information

Long-Term Safety and Efficacy of a Novel Iron-Containing Phosphate Binder, JTT-751, in Patients Receiving Hemodialysis

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