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The role of the medicinal chemist in drug discovery - then and now

Nature reviews. Drug discovery, 2004-10, Vol.3 (10), p.853-862

2004

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Discovery Heralds New Approach to the Treatment of Cystic Fibrosis

Journal of medicinal chemistry, 2014-12, Vol.57 (23), p.9774-9775

Lowe, John A

2014

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Glycine transporter type 1 blockade changes NMDA receptor-mediated responses and LTP in hippocampal CA1 pyramidal cells by altering extracellular glycine levels

The Journal of physiology, 2004-06, Vol.557 (2), p.489-500

2004

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The discovery of a structurally novel class of inhibitors of the type 1 glycine transporter

Bioorganic & medicinal chemistry letters, 2009-06, Vol.19 (11), p.2974-2976

2009

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Trends in South Asian Linguistics

1, 2021

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Discovery of a novel Kv7 channel opener as a treatment for epilepsy

Bioorganic & medicinal chemistry letters, 2015-11, Vol.25 (21), p.4941-4944

2015

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A Potent Nonpeptide Antagonist of the Substance P (NK$_1$) Receptor

Science (American Association for the Advancement of Science), 1991-01, Vol.251 (4992), p.435-437

1991

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An octahydro-cyclopenta[ c]pyrrole series of inhibitors of the type 1 glycine transporter

Bioorganic & medicinal chemistry letters, 2010-02, Vol.20 (3), p.907-911

2010

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Different binding epitopes on the NK1 receptor for substance P and a non-peptide antagonist

Nature (London), 1993-03, Vol.362 (6418), p.345-348

1993

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The modern human colonization of western Eurasia: when and where?

Quaternary science reviews, 2015-06, Vol.118, p.194-210

Hublin, Jean-Jacques

2015

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Sea-level probability for the last deglaciation: A statistical analysis of far-field records

Global and planetary change, 2011-12, Vol.79 (3), p.193-203

2011

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Improved age estimates for key Late Quaternary European tephra horizons in the RESET lattice

Quaternary science reviews, 2015-06, Vol.118, p.18-32

2015

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Structure−Activity Relationships of Potent, Selective Inhibitors of Neuronal Nitric Oxide Synthase Based on the 6-Phenyl-2-aminopyridine Structure

Journal of medicinal chemistry, 2004-03, Vol.47 (6), p.1575-1586

2004

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The major and trace element glass compositions of the productive Mediterranean volcanic sources: tools for correlating distal tephra layers in and around Europe

Quaternary science reviews, 2015-06, Vol.118, p.48-66

2015

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[ 3H]-( R)-NPTS, a radioligand for the type 1 glycine transporter

Bioorganic & medicinal chemistry letters, 2003-04, Vol.13 (7), p.1291-1292

2003

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Activity and Distribution of Binding Sites in Brain of a Nonpeptide Substance P (NK$_1$) Receptor Antagonist

Science (American Association for the Advancement of Science), 1991-01, Vol.251 (4992), p.437-439

1991

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The 8200 yr BP cold event in stable isotope records from the North Atlantic region

Global and planetary change, 2011-12, Vol.79 (3), p.288-302

2011

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Revisiting the Y-3 tephrostratigraphic marker: a new diagnostic glass geochemistry, age estimate, and details on its climatostratigraphical context

Quaternary science reviews, 2015-06, Vol.118, p.105-121

2015

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THE EFFECT OF A CULTURALLY TAILORED SUBSTANCE ABUSE PREVENTION INTERVENTION WITH PLAINS INDIAN ADOLESCENTS

Journal of cultural diversity, 2015, Vol.22 (1), p.3

2015

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A tephra lattice for Greenland and a reconstruction of volcanic events spanning 25–45 ka b2k

Quaternary science reviews, 2015-06, Vol.118, p.122-141

2015

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Substituted 6-phenyl-pyridin-2-ylamines: selective and potent inhibitors of neuronal nitric oxide synthase

Bioorganic & medicinal chemistry letters, 2004-09, Vol.14 (17), p.4511-4514

2004

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Timing of glacier response to Younger Dryas climatic cooling in Scotland

Global and planetary change, 2011-12, Vol.79 (3), p.264-274

2011

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The RESET tephra database and associated analytical tools

Quaternary science reviews, 2015-06, Vol.118, p.33-47

2015

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A comparison of the bioavailability of three dietary zinc sources using four different physiologic parameters in dogs

The Journal of nutrition, 1998-12, Vol.128 (12), p.2809S-2811S

1998

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Evaluating the transitional mosaic: frameworks of change from Neanderthals to Homo sapiens in eastern Europe

Quaternary science reviews, 2015-06, Vol.118, p.211-242

2015

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The role of the medicinal chemist in drug discovery - then and now

Discovery Heralds New Approach to the Treatment of Cystic Fibrosis

Glycine transporter type 1 blockade changes NMDA receptor-mediated responses and LTP in hippocampal CA1 pyramidal cells by altering extracellular glycine levels

The discovery of a structurally novel class of inhibitors of the type 1 glycine transporter

Trends in South Asian Linguistics

Discovery of a novel Kv7 channel opener as a treatment for epilepsy

A Potent Nonpeptide Antagonist of the Substance P (NK$_1$) Receptor

An octahydro-cyclopenta[ c]pyrrole series of inhibitors of the type 1 glycine transporter

Different binding epitopes on the NK1 receptor for substance P and a non-peptide antagonist

The modern human colonization of western Eurasia: when and where?

Sea-level probability for the last deglaciation: A statistical analysis of far-field records

Improved age estimates for key Late Quaternary European tephra horizons in the RESET lattice

Structure−Activity Relationships of Potent, Selective Inhibitors of Neuronal Nitric Oxide Synthase Based on the 6-Phenyl-2-aminopyridine Structure

The major and trace element glass compositions of the productive Mediterranean volcanic sources: tools for correlating distal tephra layers in and around Europe

[ 3H]-( R)-NPTS, a radioligand for the type 1 glycine transporter

Activity and Distribution of Binding Sites in Brain of a Nonpeptide Substance P (NK$_1$) Receptor Antagonist

The 8200 yr BP cold event in stable isotope records from the North Atlantic region

Revisiting the Y-3 tephrostratigraphic marker: a new diagnostic glass geochemistry, age estimate, and details on its climatostratigraphical context

THE EFFECT OF A CULTURALLY TAILORED SUBSTANCE ABUSE PREVENTION INTERVENTION WITH PLAINS INDIAN ADOLESCENTS

A tephra lattice for Greenland and a reconstruction of volcanic events spanning 25–45 ka b2k

Substituted 6-phenyl-pyridin-2-ylamines: selective and potent inhibitors of neuronal nitric oxide synthase

Timing of glacier response to Younger Dryas climatic cooling in Scotland

The RESET tephra database and associated analytical tools

A comparison of the bioavailability of three dietary zinc sources using four different physiologic parameters in dogs

Evaluating the transitional mosaic: frameworks of change from Neanderthals to Homo sapiens in eastern Europe

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