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The role of the medicinal chemist in drug discovery - then and now

Nature reviews. Drug discovery, 2004-10, Vol.3 (10), p.853-862

2004

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Preparation and antiinflammatory activity of some nonacidic trisubstituted imidazoles

Journal of medicinal chemistry, 1974-11, Vol.17 (11), p.1182-1188

1974

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Synthesis and antiinflammatory activity of some 3-carboxamides of 2-alkyl-4-hydroxy-2H-1,2-benzothiazine 1,1-dioxide

Journal of medicinal chemistry, 1971-12, Vol.14 (12), p.1171-1175

1971

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Novel immunosuppressive agents. Potent immunological activity of some benzothiopyrano[4,3-c]pyrazol-3-ones

Journal of medicinal chemistry, 1981-07, Vol.24 (7), p.830-834

1981

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Synthesis and antiinflammatory activity of metabolites of piroxicam

Journal of medicinal chemistry, 1981-01, Vol.24 (1), p.39-42

Lombardino, Joseph G

1981

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Recognizing, appreciating, and capturing the tacit knowledge of R&D scientists

Drug development research, 2002-10, Vol.57 (2), p.51-57

2002

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Leading science: staying informed without micromanaging (achieving and keeping the balance)

Drug development research, 2005-02, Vol.64 (2), p.99-104

2005

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Preparation of substituted 1,2-benzoisothiazolin-3-one 1,1-dioxides (o-benzoic sulfimides)

Journal of organic chemistry, 1971-07, Vol.36 (13), p.1843-1845

Lombardino, Joseph G

1971

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Recognizing, appreciating, and capturing the tacit knowledge of R&D scientists: Biotechnology challenges in the 21st century

Drug development research, 2002, Vol.57 (2), p.51-57

2002

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Preparation and New Reactions of Imidazo[1,2-a]pyridines

Journal of organic chemistry, 1965-07, Vol.30 (7), p.2403-2407

Lombardino, Joseph G

1965

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Unusual dimeric salts of 2-(3-pyridyl)-1,3-indandione

Journal of organic chemistry, 1967-06, Vol.32 (6), p.1988-1992

Lombardino, Joseph G

1967

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Sudoxicam and related N-heterocyclic carboxamides of 4-hydroxy-2H-1,2-benzothiazine 1,1-dioxide. Potent nonsteroidal antiinflammatory agents

Journal of medicinal chemistry, 1972-08, Vol.15 (8), p.848-849

1972

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Reaction of 2,3-dihydrobenzo[b]thiophen-3(2H)-one 1,1-dioxide with electrophiles

Journal of organic chemistry, 1968-10, Vol.33 (10), p.3938-3941

Lombardino, Joseph G

1968

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Potent antiinflammatory N-heterocyclic 3-carboxamides of 4-hydroxy-2-methyl-2H-1,2-benzothiazine 1,1-dioxide

Journal of medicinal chemistry, 1973-05, Vol.16 (5), p.493-496

1973

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Sulfamylguanidines

Journal of organic chemistry, 1963-03, Vol.28 (3), p.861-863

Lombardino, Joseph G

1963

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Antiinflammatory 3,4-dihydro-2-alkyl-3-oxo-2H-1,2-benzothiazine-4-carboxamide 1,1-dioxides

Journal of medicinal chemistry, 1971-10, Vol.14 (10), p.973-977

1971

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Some 3-Arylaminoquinoxaline-2-carboxylic Acids

Journal of medicinal chemistry, 1966-09, Vol.9 (5), p.770-771

Lombardino, Joseph G

1966

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4,6-Diamino-1-alkyl-1,2-dihydro-s-triazines

Journal of medicinal chemistry, 1963-03, Vol.6 (2), p.213-214

Lombardino, Joseph G

1963

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Preparation and antiinflammatory activity of some 2-arylbenzo[b] thiophen-3(2H)-one 1,1-dioxides

Journal of medicinal chemistry, 1970-03, Vol.13 (2), p.206-210

1970

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Excretion and metabolism of a nonsteroidal antiinflammatory agent, 4-hydroxy-2-methyl-2H-1,2-benzothiazine-3-carboxanilide 1,1-dioxide, in rat, dog, monkey, and man

Journal of medicinal chemistry, 1971-12, Vol.14 (12), p.1175-1177

1971

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Antinflammatory 2-aryl-1,3-indandiones

Journal of medicinal chemistry, 1968-03, Vol.11 (2), p.342-347

1968

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Preparation and Hypoglycemic Activity of Some 3,5-Disubstituted Hydantoins

Journal of medicinal chemistry, 1964-01, Vol.7 (1), p.97-101

1964

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Azo Compounds.1 A Seven-membered Cyclic Azo Compound

Journal of the American Chemical Society, 1958-05, Vol.80 (9), p.2317-2321

1958

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Piroxicam, a structurally novel anti-inflammatory compound. Mode of prostaglandin synthesis inhibition

Prostaglandins, 1980-05, Vol.19 (5), p.671-682

1980

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Piroxicam and other anti-inflammatory oxicams

Medicinal research reviews, 1982-04, Vol.2 (2), p.127-152

1982

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The role of the medicinal chemist in drug discovery - then and now

Preparation and antiinflammatory activity of some nonacidic trisubstituted imidazoles

Synthesis and antiinflammatory activity of some 3-carboxamides of 2-alkyl-4-hydroxy-2H-1,2-benzothiazine 1,1-dioxide

Novel immunosuppressive agents. Potent immunological activity of some benzothiopyrano[4,3-c]pyrazol-3-ones

Synthesis and antiinflammatory activity of metabolites of piroxicam

Recognizing, appreciating, and capturing the tacit knowledge of R&D scientists

Leading science: staying informed without micromanaging (achieving and keeping the balance)

Preparation of substituted 1,2-benzoisothiazolin-3-one 1,1-dioxides (o-benzoic sulfimides)

Recognizing, appreciating, and capturing the tacit knowledge of R&D scientists: Biotechnology challenges in the 21st century

Preparation and New Reactions of Imidazo[1,2-a]pyridines

Unusual dimeric salts of 2-(3-pyridyl)-1,3-indandione

Sudoxicam and related N-heterocyclic carboxamides of 4-hydroxy-2H-1,2-benzothiazine 1,1-dioxide. Potent nonsteroidal antiinflammatory agents

Reaction of 2,3-dihydrobenzo[b]thiophen-3(2H)-one 1,1-dioxide with electrophiles

Potent antiinflammatory N-heterocyclic 3-carboxamides of 4-hydroxy-2-methyl-2H-1,2-benzothiazine 1,1-dioxide

Sulfamylguanidines

Antiinflammatory 3,4-dihydro-2-alkyl-3-oxo-2H-1,2-benzothiazine-4-carboxamide 1,1-dioxides

Some 3-Arylaminoquinoxaline-2-carboxylic Acids

4,6-Diamino-1-alkyl-1,2-dihydro-s-triazines

Preparation and antiinflammatory activity of some 2-arylbenzo[b] thiophen-3(2H)-one 1,1-dioxides

Excretion and metabolism of a nonsteroidal antiinflammatory agent, 4-hydroxy-2-methyl-2H-1,2-benzothiazine-3-carboxanilide 1,1-dioxide, in rat, dog, monkey, and man

Antinflammatory 2-aryl-1,3-indandiones

Preparation and Hypoglycemic Activity of Some 3,5-Disubstituted Hydantoins

Azo Compounds.1 A Seven-membered Cyclic Azo Compound

Piroxicam, a structurally novel anti-inflammatory compound. Mode of prostaglandin synthesis inhibition

Piroxicam and other anti-inflammatory oxicams

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