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Detection of significantly differentially methylated regions in targeted bisulfite sequencing data

Bioinformatics, 2013-07, Vol.29 (13), p.1647-1653

2013

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An xQTL map integrates the genetic architecture of the human brain's transcriptome and epigenome

Nature neuroscience, 2017-10, Vol.20 (10), p.1418

2017

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Considerations for integrative multi‐omic approaches to explore Alzheimer's disease mechanisms

Brain pathology (Zurich, Switzerland), 2020-09, Vol.30 (5), p.984-991

2020

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Inhibition of the LSD1 (KDM1A) demethylase reactivates the all-trans-retinoic acid differentiation pathway in acute myeloid leukemia

Nature medicine, 2012-04, Vol.18 (4), p.605-611

2012

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Epigenetic dysregulation of KCa3.1 channels induces poor prognosis in lung cancer

International journal of cancer, 2015-09, Vol.137 (6), p.1306-1317

2015

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Next-Generation Sequencing Technology Reveals a Characteristic Pattern of Molecular Mutations in 72.8% of Chronic Myelomonocytic Leukemia by Detecting Frequent Alterations in TET2, CBL, RAS, and RUNX1

Journal of clinical oncology, 2010-08, Vol.28 (24), p.3858-3865

2010

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The association of epigenetic clocks in brain tissue with brain pathologies and common aging phenotypes

Neurobiology of disease, 2021-09, Vol.157, p.105428-105428, Article 105428

2021

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Characterization of mitochondrial DNA quantity and quality in the human aged and Alzheimer's disease brain

Molecular neurodegeneration, 2021-11, Vol.16 (1), p.75-75, Article 75

2021

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demuxmix: demultiplexing oligonucleotide-barcoded single-cell RNA sequencing data with regression mixture models

Bioinformatics (Oxford, England), 2023-08, Vol.39 (8)

2023

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Diurnal and seasonal molecular rhythms in human neocortex and their relation to Alzheimer's disease

Nature communications, 2017-04, Vol.8 (1), p.14931-14931, Article 14931

2017

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Identification of genes associated with dissociation of cognitive performance and neuropathological burden: Multistep analysis of genetic, epigenetic, and transcriptional data

PLoS medicine, 2017-04, Vol.14 (4), p.e1002287-e1002287

2017

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Genomic instability may originate from imatinib-refractory chronic myeloid leukemia stem cells

Blood, 2013-05, Vol.121 (20), p.4175-4183

2013

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Comparative study of unsupervised dimension reduction techniques for the visualization of microarray gene expression data

BMC bioinformatics, 2010-11, Vol.11 (1), p.567-567, Article 567

2010

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Atlas of RNA editing events affecting protein expression in aged and Alzheimer's disease human brain tissue

Nature communications, 2021-12, Vol.12 (1), p.7035-7035, Article 7035

2021

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Integration of GWAS and brain transcriptomic analyses in a multiethnic sample of 35,245 older adults identifies DCDC2 gene as predictor of episodic memory maintenance

Alzheimer's & dementia, 2022-10, Vol.18 (10), p.1797-1811

2022

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Proximal and distal effects of genetic susceptibility to multiple sclerosis on the T cell epigenome

Nature communications, 2021-12, Vol.12 (1), p.7078-7078, Article 7078

2021

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Epigenomic features related to microglia are associated with attenuated effect of APOE ε4 on Alzheimer's disease risk in humans

Alzheimer's & dementia, 2022-04, Vol.18 (4), p.688-699

2022

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Cell-type-specific Alzheimer's disease polygenic risk scores are associated with distinct disease processes in Alzheimer's disease

Nature communications, 2023-11, Vol.14 (1), p.7659-7659, Article 7659

2023

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Bayesian integrative analysis of epigenomic and transcriptomic data identifies Alzheimer's disease candidate genes and networks

PLoS computational biology, 2020-04, Vol.16 (4), p.e1007771-e1007771

2020

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Cortical proteins may provide motor resilience in older adults

Scientific reports, 2021-05, Vol.11 (1), p.11311-11311, Article 11311

2021

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Multi‐region brain transcriptomes uncover two subtypes of aging individuals with differences in the impact of APOEe4

Alzheimer's & dementia, 2021-12, Vol.17 (S3), p.e057240-n/a

2021

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Cell type‐specific Alzheimer’s disease polygenic risk scores are associated with distinct disease processes in preclinical Alzheimer’s disease

Alzheimer's & dementia, 2021-12, Vol.17, p.e055304-n/a

2021

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BIN1 protein isoforms are differentially expressed in astrocytes, neurons, and microglia: neuronal and astrocyte BIN1 are implicated in tau pathology

Molecular neurodegeneration, 2020-07, Vol.15 (1), p.44-44, Article 44

2020

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Epigenomic features related to microglia are associated with attenuated effect of APOE ε4 on Alzheimer’s disease risk in humans

Alzheimer's & dementia, 2020-12, Vol.16 (Suppl 2), p.n/a

2020

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A cortical immune network map identifies distinct microglial transcriptional programs associated with β-amyloid and Tau pathologies

Translational psychiatry, 2021-01, Vol.11 (1), p.50-50, Article 50

2021

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Detection of significantly differentially methylated regions in targeted bisulfite sequencing data

An xQTL map integrates the genetic architecture of the human brain's transcriptome and epigenome

Considerations for integrative multi‐omic approaches to explore Alzheimer's disease mechanisms

Inhibition of the LSD1 (KDM1A) demethylase reactivates the all-trans-retinoic acid differentiation pathway in acute myeloid leukemia

Epigenetic dysregulation of KCa3.1 channels induces poor prognosis in lung cancer

Next-Generation Sequencing Technology Reveals a Characteristic Pattern of Molecular Mutations in 72.8% of Chronic Myelomonocytic Leukemia by Detecting Frequent Alterations in TET2, CBL, RAS, and RUNX1

The association of epigenetic clocks in brain tissue with brain pathologies and common aging phenotypes

Characterization of mitochondrial DNA quantity and quality in the human aged and Alzheimer's disease brain

demuxmix: demultiplexing oligonucleotide-barcoded single-cell RNA sequencing data with regression mixture models

Diurnal and seasonal molecular rhythms in human neocortex and their relation to Alzheimer's disease

Identification of genes associated with dissociation of cognitive performance and neuropathological burden: Multistep analysis of genetic, epigenetic, and transcriptional data

Genomic instability may originate from imatinib-refractory chronic myeloid leukemia stem cells

Comparative study of unsupervised dimension reduction techniques for the visualization of microarray gene expression data

Atlas of RNA editing events affecting protein expression in aged and Alzheimer's disease human brain tissue

Integration of GWAS and brain transcriptomic analyses in a multiethnic sample of 35,245 older adults identifies DCDC2 gene as predictor of episodic memory maintenance

Proximal and distal effects of genetic susceptibility to multiple sclerosis on the T cell epigenome

Epigenomic features related to microglia are associated with attenuated effect of APOE ε4 on Alzheimer's disease risk in humans

Cell-type-specific Alzheimer's disease polygenic risk scores are associated with distinct disease processes in Alzheimer's disease

Bayesian integrative analysis of epigenomic and transcriptomic data identifies Alzheimer's disease candidate genes and networks

Cortical proteins may provide motor resilience in older adults

Multi‐region brain transcriptomes uncover two subtypes of aging individuals with differences in the impact of APOEe4

Cell type‐specific Alzheimer’s disease polygenic risk scores are associated with distinct disease processes in preclinical Alzheimer’s disease

BIN1 protein isoforms are differentially expressed in astrocytes, neurons, and microglia: neuronal and astrocyte BIN1 are implicated in tau pathology

Epigenomic features related to microglia are associated with attenuated effect of APOE ε4 on Alzheimer’s disease risk in humans

A cortical immune network map identifies distinct microglial transcriptional programs associated with β-amyloid and Tau pathologies

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