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Human iPSC-Derived Natural Killer Cells Engineered with Chimeric Antigen Receptors Enhance Anti-tumor Activity

Cell stem cell, 2018-08, Vol.23 (2), p.181-192.e5

2018

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Utilizing chimeric antigen receptors to direct natural killer cell activity

Frontiers in immunology, 2015-04, Vol.6, p.195-195

2015

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Toward clinical therapies using hematopoietic cells derived from human pluripotent stem cells

Blood, 2009-10, Vol.114 (17), p.3513-3523

Kaufman, Dan S.

2009

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Metabolic Reprograming via Deletion of CISH in Human iPSC-Derived NK Cells Promotes In Vivo Persistence and Enhances Anti-tumor Activity

Cell stem cell, 2020-08, Vol.27 (2), p.224-237.e6

2020

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Cardiac Repair in a Porcine Model of Acute Myocardial Infarction with Human Induced Pluripotent Stem Cell-Derived Cardiovascular Cells

Cell stem cell, 2014-12, Vol.15 (6), p.750-761

2014

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iPSC-Derived Natural Killer Cell Therapies - Expansion and Targeting

Frontiers in immunology, 2022-02, Vol.13, p.841107-841107

2022

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Identification of an ADAM17 cleavage region in human CD16 (FcγRIII) and the engineering of a non-cleavable version of the receptor in NK cells

PloS one, 2015-03, Vol.10 (3), p.e0121788

2015

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Induced Pluripotent Stem Cell‐Derived Natural Killer Cells for Treatment of Ovarian Cancer

Stem cells (Dayton, Ohio), 2016-01, Vol.34 (1), p.93-101

2016

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Development of innate immune cells from human pluripotent stem cells

Experimental hematology, 2019-03, Vol.71, p.13-23

2019

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Pluripotent stem cell–derived NK cells with high-affinity noncleavable CD16a mediate improved antitumor activity

Blood, 2020-02, Vol.135 (6), p.399-410

2020

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Off-the-shelf cell therapy with induced pluripotent stem cell-derived natural killer cells

Seminars in immunopathology, 2019-01, Vol.41 (1), p.59-68

2019

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Induced pluripotent stem cell-derived engineered T cells, natural killer cells, macrophages, and dendritic cells in immunotherapy

Trends in biotechnology (Regular ed.), 2023-07, Vol.41 (7), p.907-922

2023

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Into the multiverse of gene edited NK cell-based therapeutic strategies

Cell stem cell, 2021-12, Vol.28 (12), p.2041-2043

2021

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iPSC-derived NK cells maintain high cytotoxicity and enhance in vivo tumor control in concert with T cells and anti-PD-1 therapy

Science translational medicine, 2020-11, Vol.12 (568)

2020

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Expression of Chimeric Receptor CD4ζ by Natural Killer Cells Derived from Human Pluripotent Stem Cells Improves In Vitro Activity but Does Not Enhance Suppression of HIV Infection In Vivo

Stem cells (Dayton, Ohio), 2014-04, Vol.32 (4), p.1021-1031

2014

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RUNX1a enhances hematopoietic lineage commitment from human embryonic stem cells and inducible pluripotent stem cells

Blood, 2013-04, Vol.121 (15), p.2882-2890

2013

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Clinical‐Scale Derivation of Natural Killer Cells From Human Pluripotent Stem Cells for Cancer Therapy

Stem cells translational medicine, 2013-04, Vol.2 (4), p.274-283

2013

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Clinical-grade generation of active NK cells from cord blood hematopoietic progenitor cells for immunotherapy using a closed-system culture process

PloS one, 2011-06, Vol.6 (6), p.e20740-e20740

2011

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Fibrinogen Induces RUNX2 Activity and Osteogenic Development from Human Pluripotent Stem Cells

Stem cells (Dayton, Ohio), 2016-08, Vol.34 (8), p.2079-2089

2016

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CHMP2A regulates tumor sensitivity to natural killer cell-mediated cytotoxicity

Nature communications, 2022-04, Vol.13 (1), p.1899-1899, Article 1899

2022

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Human induced pluripotent stem cell‐derived macrophages ameliorate liver fibrosis

Stem cells (Dayton, Ohio), 2021-12, Vol.39 (12), p.1701-1717

2021

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Umbilical Cord Blood and iPSC-Derived Natural Killer Cells Demonstrate Key Differences in Cytotoxic Activity and KIR Profiles

Frontiers in immunology, 2020-10, Vol.11, p.561553-561553

2020

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Expression of a Recombinant High Affinity IgG Fc Receptor by Engineered NK Cells as a Docking Platform for Therapeutic mAbs to Target Cancer Cells

Frontiers in immunology, 2018-12, Vol.9, p.2873-2873

2018

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Lineage‐specific differentiation of osteogenic progenitors from pluripotent stem cells reveals the FGF1‐RUNX2 association in neural crest‐derived osteoprogenitors

Stem cells (Dayton, Ohio), 2020-09, Vol.38 (9), p.1107-1123

2020

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A Fibrin Patch‐Based Enhanced Delivery of Human Embryonic Stem Cell‐Derived Vascular Cell Transplantation in a Porcine Model of Postinfarction Left Ventricular Remodeling

Stem cells (Dayton, Ohio), 2011-02, Vol.29 (2), p.367-375

2011

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Human iPSC-Derived Natural Killer Cells Engineered with Chimeric Antigen Receptors Enhance Anti-tumor Activity

Utilizing chimeric antigen receptors to direct natural killer cell activity

Toward clinical therapies using hematopoietic cells derived from human pluripotent stem cells

Metabolic Reprograming via Deletion of CISH in Human iPSC-Derived NK Cells Promotes In Vivo Persistence and Enhances Anti-tumor Activity

Cardiac Repair in a Porcine Model of Acute Myocardial Infarction with Human Induced Pluripotent Stem Cell-Derived Cardiovascular Cells

iPSC-Derived Natural Killer Cell Therapies - Expansion and Targeting

Identification of an ADAM17 cleavage region in human CD16 (FcγRIII) and the engineering of a non-cleavable version of the receptor in NK cells

Induced Pluripotent Stem Cell‐Derived Natural Killer Cells for Treatment of Ovarian Cancer

Development of innate immune cells from human pluripotent stem cells

Pluripotent stem cell–derived NK cells with high-affinity noncleavable CD16a mediate improved antitumor activity

Off-the-shelf cell therapy with induced pluripotent stem cell-derived natural killer cells

Induced pluripotent stem cell-derived engineered T cells, natural killer cells, macrophages, and dendritic cells in immunotherapy

Into the multiverse of gene edited NK cell-based therapeutic strategies

iPSC-derived NK cells maintain high cytotoxicity and enhance in vivo tumor control in concert with T cells and anti-PD-1 therapy

Expression of Chimeric Receptor CD4ζ by Natural Killer Cells Derived from Human Pluripotent Stem Cells Improves In Vitro Activity but Does Not Enhance Suppression of HIV Infection In Vivo

RUNX1a enhances hematopoietic lineage commitment from human embryonic stem cells and inducible pluripotent stem cells

Clinical‐Scale Derivation of Natural Killer Cells From Human Pluripotent Stem Cells for Cancer Therapy

Clinical-grade generation of active NK cells from cord blood hematopoietic progenitor cells for immunotherapy using a closed-system culture process

Fibrinogen Induces RUNX2 Activity and Osteogenic Development from Human Pluripotent Stem Cells

CHMP2A regulates tumor sensitivity to natural killer cell-mediated cytotoxicity

Human induced pluripotent stem cell‐derived macrophages ameliorate liver fibrosis

Umbilical Cord Blood and iPSC-Derived Natural Killer Cells Demonstrate Key Differences in Cytotoxic Activity and KIR Profiles

Expression of a Recombinant High Affinity IgG Fc Receptor by Engineered NK Cells as a Docking Platform for Therapeutic mAbs to Target Cancer Cells

Lineage‐specific differentiation of osteogenic progenitors from pluripotent stem cells reveals the FGF1‐RUNX2 association in neural crest‐derived osteoprogenitors

A Fibrin Patch‐Based Enhanced Delivery of Human Embryonic Stem Cell‐Derived Vascular Cell Transplantation in a Porcine Model of Postinfarction Left Ventricular Remodeling

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