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NK cell CD16 surface expression and function is regulated by a disintegrin and metalloprotease-17 (ADAM17)

Blood, 2013-05, Vol.121 (18), p.3599-3608

2013

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Engineering Anti-Tumor Monoclonal Antibodies and Fc Receptors to Enhance ADCC by Human NK Cells

Cancers, 2021-01, Vol.13 (2), p.312

2021

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A Genetically Engineered Primary Human Natural Killer Cell Platform for Cancer Immunotherapy

Molecular therapy, 2020-01, Vol.28 (1), p.52-63

2020

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Identification of an ADAM17 cleavage region in human CD16 (FcγRIII) and the engineering of a non-cleavable version of the receptor in NK cells

PloS one, 2015-03, Vol.10 (3), p.e0121788

2015

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Quadruple gene-engineered natural killer cells enable multi-antigen targeting for durable antitumor activity against multiple myeloma

Nature communications, 2022-11, Vol.13 (1), p.7341-7341, Article 7341

2022

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Ectodomain Shedding by ADAM17: Its Role in Neutrophil Recruitment and the Impairment of This Process during Sepsis

Frontiers in cellular and infection microbiology, 2017-04, Vol.7, p.138-138

2017

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Ectodomain shedding of the cell adhesion molecule Nectin-4 in ovarian cancer is mediated by ADAM10 and ADAM17

The Journal of biological chemistry, 2017-04, Vol.292 (15), p.6339-6351

2017

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Blocking ADAM17 Function with a Monoclonal Antibody Improves Sepsis Survival in a Murine Model of Polymicrobial Sepsis

International journal of molecular sciences, 2020-09, Vol.21 (18), p.6688

2020

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Activation of ADAM17 by IL-15 Limits Human NK Cell Proliferation

Frontiers in immunology, 2021-07, Vol.12, p.711621-711621

2021

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Expression of a Recombinant High Affinity IgG Fc Receptor by Engineered NK Cells as a Docking Platform for Therapeutic mAbs to Target Cancer Cells

Frontiers in immunology, 2018-12, Vol.9, p.2873-2873

2018

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Role of ADAM17 in the ectodomain shedding of TNF-α and its receptors by neutrophils and macrophages

Journal of leukocyte biology, 2007-07, Vol.82 (1), p.173-176

2007

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Regulation of Mature ADAM17 by Redox Agents for L-Selectin Shedding

The Journal of immunology (1950), 2009-02, Vol.182 (4), p.2449-2457

2009

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Association between MICA polymorphisms, s-MICA levels, and pancreatic cancer risk in a population-based case-control study

PloS one, 2019-06, Vol.14 (6), p.e0217868-e0217868

2019

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An ADAM17-Neutralizing Antibody Reduces Inflammation and Mortality While Increasing Viral Burden in a COVID-19 Mouse Model

Frontiers in immunology, 2022-06, Vol.13, p.918881-918881

2022

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Different Signaling Pathways Stimulate a Disintegrin and Metalloprotease-17 (ADAM17) in Neutrophils during Apoptosis and Activation

The Journal of biological chemistry, 2011-11, Vol.286 (45), p.38980-38988

2011

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508 IL-15-stimulated NK cell proliferation is greatly augmented by the anti-ADAM17 mAb Medi-1 and requires CD137

Journal for immunotherapy of cancer, 2023-11, Vol.11 (Suppl 1), p.A571-A572

2023

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Examination of IgG Fc Receptor CD16A and CD64 Expression by Canine Leukocytes and Their ADCC Activity in Engineered NK Cells

Frontiers in immunology, 2022-02, Vol.13, p.841859-841859

2022

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In vivo role of leukocyte ADAM17 in the inflammatory and host responses during E. coli-mediated peritonitis

Journal of leukocyte biology, 2010-06, Vol.87 (6), p.1097-1101

2010

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Functional Interactions between Tumor and Peripheral Nerve: Morphology, Algogen Identification, and Behavioral Characterization of a New Murine Model of Cancer Pain

The Journal of neuroscience, 2001-12, Vol.21 (23), p.9355-9366

2001

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ADAM17 activation in circulating neutrophils following bacterial challenge impairs their recruitment

Journal of leukocyte biology, 2012-09, Vol.92 (3), p.667-672

2012

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Detection of Antibody-Dependent Cell-Mediated Cytotoxicity-Supporting Antibodies by NK-92-CD16A Cell Externalization of CD107a: Recognition of Antibody Afucosylation and Assay Optimization

Antibodies (Basel), 2023-06, Vol.12 (3), p.44

2023

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Leukocyte ADAM17 regulates acute pulmonary inflammation

PloS one, 2011-05, Vol.6 (5), p.e19938-e19938

2011

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iPSC-derived natural killer cells expressing the FcγR fusion CD64/16A can be armed with antibodies for multitumor antigen targeting

Journal for immunotherapy of cancer, 2023-12, Vol.11 (12), p.e007280

2023

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Enhancement of NK Cell Antitumor Effector Functions Using a Bispecific Single Domain Antibody Targeting CD16 and the Epidermal Growth Factor Receptor

Cancers, 2021-10, Vol.13 (21), p.5446

2021

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NK cell CD16 surface expression and function is regulated by a disintegrin and metalloprotease-17 (ADAM17)

Engineering Anti-Tumor Monoclonal Antibodies and Fc Receptors to Enhance ADCC by Human NK Cells

A Genetically Engineered Primary Human Natural Killer Cell Platform for Cancer Immunotherapy

Identification of an ADAM17 cleavage region in human CD16 (FcγRIII) and the engineering of a non-cleavable version of the receptor in NK cells

Quadruple gene-engineered natural killer cells enable multi-antigen targeting for durable antitumor activity against multiple myeloma

Ectodomain Shedding by ADAM17: Its Role in Neutrophil Recruitment and the Impairment of This Process during Sepsis

Ectodomain shedding of the cell adhesion molecule Nectin-4 in ovarian cancer is mediated by ADAM10 and ADAM17

Blocking ADAM17 Function with a Monoclonal Antibody Improves Sepsis Survival in a Murine Model of Polymicrobial Sepsis

Activation of ADAM17 by IL-15 Limits Human NK Cell Proliferation

Expression of a Recombinant High Affinity IgG Fc Receptor by Engineered NK Cells as a Docking Platform for Therapeutic mAbs to Target Cancer Cells

Role of ADAM17 in the ectodomain shedding of TNF-α and its receptors by neutrophils and macrophages

Regulation of Mature ADAM17 by Redox Agents for L-Selectin Shedding

Association between MICA polymorphisms, s-MICA levels, and pancreatic cancer risk in a population-based case-control study

An ADAM17-Neutralizing Antibody Reduces Inflammation and Mortality While Increasing Viral Burden in a COVID-19 Mouse Model

Different Signaling Pathways Stimulate a Disintegrin and Metalloprotease-17 (ADAM17) in Neutrophils during Apoptosis and Activation

Tumor-induced MDSC act via remote control to inhibit L-selectin-dependent adaptive immunity in lymph nodes

508 IL-15-stimulated NK cell proliferation is greatly augmented by the anti-ADAM17 mAb Medi-1 and requires CD137

Examination of IgG Fc Receptor CD16A and CD64 Expression by Canine Leukocytes and Their ADCC Activity in Engineered NK Cells

In vivo role of leukocyte ADAM17 in the inflammatory and host responses during E. coli-mediated peritonitis

Functional Interactions between Tumor and Peripheral Nerve: Morphology, Algogen Identification, and Behavioral Characterization of a New Murine Model of Cancer Pain

ADAM17 activation in circulating neutrophils following bacterial challenge impairs their recruitment

Detection of Antibody-Dependent Cell-Mediated Cytotoxicity-Supporting Antibodies by NK-92-CD16A Cell Externalization of CD107a: Recognition of Antibody Afucosylation and Assay Optimization

Leukocyte ADAM17 regulates acute pulmonary inflammation

iPSC-derived natural killer cells expressing the FcγR fusion CD64/16A can be armed with antibodies for multitumor antigen targeting

Enhancement of NK Cell Antitumor Effector Functions Using a Bispecific Single Domain Antibody Targeting CD16 and the Epidermal Growth Factor Receptor

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