UB Paderborn / Katalog / Suche / in CDI

1 – 25 von 33

Sortiert nach

Discovery of the Soluble Guanylate Cyclase Stimulator Vericiguat (BAY 1021189) for the Treatment of Chronic Heart Failure

Journal of medicinal chemistry, 2017-06, Vol.60 (12), p.5146-5161

2017

Link zum Volltext

Verfügbarkeit prüfen

Preclinical Efficacy of the Auristatin-Based Antibody-Drug Conjugate BAY 1187982 for the Treatment of FGFR2-Positive Solid Tumors

Cancer research (Chicago, Ill.), 2016-11, Vol.76 (21), p.6331-6339

2016

Link zum Volltext

Verfügbarkeit prüfen

Preclinical Antitumor Efficacy of BAY 1129980-a Novel Auristatin-Based Anti-C4.4A (LYPD3) Antibody-Drug Conjugate for the Treatment of Non-Small Cell Lung Cancer

Molecular cancer therapeutics, 2017-05, Vol.16 (5), p.893-904

2017

Link zum Volltext

Verfügbarkeit prüfen

The Lab Oddity Prevails: Discovery of Pan-CDK Inhibitor (R)-S-Cyclopropyl-S-(4-{[4-{[(1R,2R)-2-hydroxy-1-methylpropyl]oxy}-5-(trifluoromethyl)pyrimidin-2-yl]amino}phenyl)sulfoximide (BAY 1000394) for the Treatment of Cancer

ChemMedChem, 2013-07, Vol.8 (7), p.1067-1085

2013

Link zum Volltext

Verfügbarkeit prüfen

Studies towards Trichodimerol: Novel Cascade Reactions and Polycyclic Frameworks

Chemistry : a European journal, 1999-12, Vol.5 (12), p.3651-3665

1999

Link zum Volltext

Verfügbarkeit prüfen

Discovery of Rogaratinib (BAY 1163877): a pan‐FGFR Inhibitor

ChemMedChem, 2018-03, Vol.13 (5), p.437-445

2018

Link zum Volltext

Verfügbarkeit prüfen

Abstract 46: Preclinical activity of novel antibody-drug conjugates with pyrrole-based kinesin spindle protein inhibitors targeting different tumor antigens

Cancer research (Chicago, Ill.), 2017-07, Vol.77 (13_Supplement), p.46-46

2017

Link zum Volltext

Verfügbarkeit prüfen

Abstract 3234: Development of potent and selective antibody-drug conjugates with pyrrole-based KSP inhibitors as novel payload class

Cancer research (Chicago, Ill.), 2017-07, Vol.77 (13_Supplement), p.3234-3234

2017

Link zum Volltext

Verfügbarkeit prüfen

Auf der ersten Etappe von der Idee zum Arzneimittel

Nachrichten aus der Chemie, 2004-01, Vol.52 (1), p.105-107

Jautelat, Rolf

2004

Link zum Volltext

Verfügbarkeit prüfen

Abstract 4332: Discovery of BAY 1163877 - A pan-FGFR inhibitor: De novo structure-based design and lead optimization of benzothiophenyl-pyrrolotriazines

Cancer research (Chicago, Ill.), 2016-07, Vol.76 (14_Supplement), p.4332-4332

2016

Link zum Volltext

Verfügbarkeit prüfen

Abstract 1739: Preclinical profile of BAY 1163877 - a selective pan-FGFR inhibitor in phase 1 clinical trial

Cancer research (Chicago, Ill.), 2014-10, Vol.74 (19_Supplement), p.1739-1739

2014

Link zum Volltext

Verfügbarkeit prüfen

Abstract 4491: FGFR2-ADC potently and selectively inhibits growth of gastric and breast cancer xenograft models

Cancer research (Chicago, Ill.), 2014-10, Vol.74 (19_Supplement), p.4491-4491

2014

Link zum Volltext

Verfügbarkeit prüfen

From the Insoluble Dye Indirubin towards Highly Active, Soluble CDK2-Inhibitors

Chembiochem : a European journal of chemical biology, 2005-03, Vol.6 (3), p.531-540

2005

Link zum Volltext

Verfügbarkeit prüfen

Abstract 5445: Preclinical anti-tumor efficacy of an anti-C4.4a (LYPD3) antibody drug conjugate for the treatment of lung squamous cell carcinoma

Cancer research (Chicago, Ill.), 2014-10, Vol.74 (19_Supplement), p.5445-5445

2014

Link zum Volltext

Verfügbarkeit prüfen

Macrocyclic Aminopyrimidines as Multitarget CDK and VEGF-R Inhibitors with Potent Antiproliferative Activities

ChemMedChem, 2007-01, Vol.2 (1), p.63-77

2007

Link zum Volltext

Verfügbarkeit prüfen

Cover Picture: The Lab Oddity Prevails: Discovery of Pan-CDK Inhibitor (R)-S-Cyclopropyl-S-(4-{[4-{[(1R,2R)-2-hydroxy-1-methylpropyl]oxy}-5-(trifluoromethyl)pyrimidin-2-yl]amino}phenyl)sulfoximide (BAY 1000394) for the Treatment of Cancer (ChemMedChem 7/2013)

ChemMedChem, 2013-07, Vol.8 (7), p.1021-1021

2013

Link zum Volltext

Verfügbarkeit prüfen

Auf der ersten Etappe von der Idee zum Arzneimittel

Nachrichten aus der Chemie, 2004-01, Vol.52 (1), p.105-107

Jautelat, Rolf

2004

Link zum Volltext

Verfügbarkeit prüfen

Synthesis of Cephalostatin Analogues by Symmetrical and Non-Symmetrical Routes

European journal of organic chemistry, 1998-12, Vol.1998 (12), p.2811-2831

1998

Link zum Volltext

Verfügbarkeit prüfen

Synthesis of Cytostatic Tetradecacyclic Pyrazines and a Novel Reduction-Oxidation Sequence for Spiroketal Opening in Sapogenins

Helvetica chimica acta, 2000-08, Vol.83 (8), p.1854-1880

2000

Link zum Volltext

Verfügbarkeit prüfen

Directed Synthesis of Nonsymmetrical Bis-Steroidal Pyrazines and the First Biologically Active Cephalostatin Analogues

Angewandte Chemie (International ed.), 1996-07, Vol.35 (13-14), p.1572-1574

1996

Link zum Volltext

Verfügbarkeit prüfen

Kinase Data Mining: Dealing with the Information (Over-)Flow

ChemBioChem, 2005-03, Vol.6 (3), p.567-570

2005

Link zum Volltext

Verfügbarkeit prüfen

A Novel Oxidative Cleavage of the Steroidal Skeleton

Chemistry : a European journal, 1999-04, Vol.5 (4), p.1226-1233

1999

Link zum Volltext

Verfügbarkeit prüfen

A Novel Route to the Fused Maleic Anhydride Moiety of CP Molecules

Angewandte Chemie (International ed.), 1999-02, Vol.38 (4), p.549-552

1999

Link zum Volltext

Verfügbarkeit prüfen

1 – 25 von 33

Suche als RSS-Feed

Suchergebnisse filtern

Filter anzeigen

Nur zeigen

Geprüft (Peer-Review)
(29)
Mit Volltextzugriff
(32)

Publikationsform

Artikel
(33)

Sprache

Erscheinungsjahr

n.n

Thema

Science & Technology
(14)
Life Sciences & Biomedicine
(9)
Humans
(8)
Chemistry, Medicinal
(7)
Pharmacology & Pharmacy
(7)
Animals
(6)
Medicinal Chemistry
(6)
Chemistry
(5)
Physical Sciences
(5)
Biological Activity
(4)
Cell Line, Tumor
(4)
Chemistry, Multidisciplinary
(4)
Molecular Structure
(4)
Protein Kinase Inhibitors - Pharmacology
(4)
Structure-Activity Relationship
(4)
Antibiotics
(3)
Antitumor Agents
(3)
Cephalostatins
(3)
Drug Discovery
(3)
Mice
(3)

15 weitere anzeigen...

Weniger anzeigen...

Zeitschrift / Serie

5 weitere anzeigen...

Weniger anzeigen...

Menü

Weitere Dienste

Einstellungen

Discovery of the Soluble Guanylate Cyclase Stimulator Vericiguat (BAY 1021189) for the Treatment of Chronic Heart Failure

Preclinical Efficacy of the Auristatin-Based Antibody-Drug Conjugate BAY 1187982 for the Treatment of FGFR2-Positive Solid Tumors

Preclinical Antitumor Efficacy of BAY 1129980-a Novel Auristatin-Based Anti-C4.4A (LYPD3) Antibody-Drug Conjugate for the Treatment of Non-Small Cell Lung Cancer

The Lab Oddity Prevails: Discovery of Pan-CDK Inhibitor (R)-S-Cyclopropyl-S-(4-{[4-{[(1R,2R)-2-hydroxy-1-methylpropyl]oxy}-5-(trifluoromethyl)pyrimidin-2-yl]amino}phenyl)sulfoximide (BAY 1000394) for the Treatment of Cancer

Treating Cancer by Spindle Assembly Checkpoint Abrogation: Discovery of Two Clinical Candidates, BAY 1161909 and BAY 1217389, Targeting MPS1 Kinase

Studies towards Trichodimerol: Novel Cascade Reactions and Polycyclic Frameworks

New Generation of sGC Stimulators: Discovery of Imidazo[1,2‑a]pyridine Carboxamide BAY 1165747 (BAY-747), a Long-Acting Soluble Guanylate Cyclase Stimulator for the Treatment of Resistant Hypertension

Discovery of Rogaratinib (BAY 1163877): a pan‐FGFR Inhibitor

Abstract 46: Preclinical activity of novel antibody-drug conjugates with pyrrole-based kinesin spindle protein inhibitors targeting different tumor antigens

Abstract 3234: Development of potent and selective antibody-drug conjugates with pyrrole-based KSP inhibitors as novel payload class

Auf der ersten Etappe von der Idee zum Arzneimittel

Abstract 4332: Discovery of BAY 1163877 - A pan-FGFR inhibitor: De novo structure-based design and lead optimization of benzothiophenyl-pyrrolotriazines

Abstract 1739: Preclinical profile of BAY 1163877 - a selective pan-FGFR inhibitor in phase 1 clinical trial

Abstract 4491: FGFR2-ADC potently and selectively inhibits growth of gastric and breast cancer xenograft models

From the Insoluble Dye Indirubin towards Highly Active, Soluble CDK2-Inhibitors

Abstract 5445: Preclinical anti-tumor efficacy of an anti-C4.4a (LYPD3) antibody drug conjugate for the treatment of lung squamous cell carcinoma

Macrocyclic Aminopyrimidines as Multitarget CDK and VEGF-R Inhibitors with Potent Antiproliferative Activities

Cover Picture: The Lab Oddity Prevails: Discovery of Pan-CDK Inhibitor (R)-S-Cyclopropyl-S-(4-{[4-{[(1R,2R)-2-hydroxy-1-methylpropyl]oxy}-5-(trifluoromethyl)pyrimidin-2-yl]amino}phenyl)sulfoximide (BAY 1000394) for the Treatment of Cancer (ChemMedChem 7/2013)

Auf der ersten Etappe von der Idee zum Arzneimittel

Synthesis of Cephalostatin Analogues by Symmetrical and Non-Symmetrical Routes

Synthesis of Cytostatic Tetradecacyclic Pyrazines and a Novel Reduction-Oxidation Sequence for Spiroketal Opening in Sapogenins

Directed Synthesis of Nonsymmetrical Bis-Steroidal Pyrazines and the First Biologically Active Cephalostatin Analogues

Kinase Data Mining: Dealing with the Information (Over-)Flow

A Novel Oxidative Cleavage of the Steroidal Skeleton

A Novel Route to the Fused Maleic Anhydride Moiety of CP Molecules

Suchergebnisse filtern