UB Paderborn / Katalog / Suche / in CDI

1 – 25 von 520

Sortiert nach

The Pharmacogene Variation (PharmVar) Consortium: Incorporation of the Human Cytochrome P450 (CYP) Allele Nomenclature Database

Clinical pharmacology and therapeutics, 2018-03, Vol.103 (3), p.399-401

2018

Link zum Volltext

Verfügbarkeit prüfen

Endogenous and xenobiotic metabolic stability of primary human hepatocytes in long‐term 3D spheroid cultures revealed by a combination of targeted and untargeted metabolomics

The FASEB journal, 2017-06, Vol.31 (6), p.2696-2708

2017

Link zum Volltext

Verfügbarkeit prüfen

3D human liver spheroids for translational pharmacology and toxicology

Basic & clinical pharmacology & toxicology, 2022-01, Vol.130 (S1), p.5-15

2022

Link zum Volltext

Verfügbarkeit prüfen

How to Consider Rare Genetic Variants in Personalized Drug Therapy

Clinical pharmacology and therapeutics, 2018-05, Vol.103 (5), p.745-748

2018

Link zum Volltext

Verfügbarkeit prüfen

Development of the PGx‐Passport: A Panel of Actionable Germline Genetic Variants for Pre‐Emptive Pharmacogenetic Testing

Clinical pharmacology and therapeutics, 2019-10, Vol.106 (4), p.866-873

2019

Link zum Volltext

Verfügbarkeit prüfen

Massive rearrangements of cellular MicroRNA signatures are key drivers of hepatocyte dedifferentiation

Hepatology (Baltimore, Md.), 2016-11, Vol.64 (5), p.1743-1756

2016

Link zum Volltext

Verfügbarkeit prüfen

Transcriptional and post-transcriptional regulation of the pregnane X receptor: a rationale for interindividual variability in drug metabolism

Archives of toxicology, 2021-01, Vol.95 (1), p.11-25

2021

Link zum Volltext

Verfügbarkeit prüfen

A 3D Cell Culture Model Identifies Wnt/β‐Catenin Mediated Inhibition of p53 as a Critical Step during Human Hepatocyte Regeneration

Advanced science, 2020-08, Vol.7 (15), p.2000248-n/a

2020

Link zum Volltext

Verfügbarkeit prüfen

Evidence-based selection of training compounds for use in the mechanism-based integrated prediction of drug-induced liver injury in man

Archives of toxicology, 2016-12, Vol.90 (12), p.2979-3003

2016

Link zum Volltext

Verfügbarkeit prüfen

Impact of the novel CYP2C:TG haplotype and CYP2B6 variants on sertraline exposure in a large patient population

Clinical and translational science, 2022-09, Vol.15 (9), p.2135-2145

2022

Link zum Volltext

Verfügbarkeit prüfen

Effect of the NFIB rs28379954 T>C polymorphism on CYP2D6‐catalyzed metabolism of solanidine

Clinical and translational science, 2024-02, Vol.17 (2), p.e13743-n/a

2024

Link zum Volltext

Verfügbarkeit prüfen

Increased omeprazole metabolism in carriers of the CYP2C1917 allele; a pharmacokinetic study in healthy volunteers

British journal of clinical pharmacology, 2008-05, Vol.65 (5), p.767-774

2008

Link zum Volltext

Verfügbarkeit prüfen

The humanised CYP2C19 transgenic mouse exhibits cerebellar atrophy and movement impairment reminiscent of ataxia

Neuropathology and applied neurobiology, 2023-02, Vol.49 (1), p.e12867-n/a

2023

Link zum Volltext

Verfügbarkeit prüfen

Precision medicine in cardiovascular therapeutics: Evaluating the role of pharmacogenetic analysis prior to drug treatment

Journal of internal medicine, 2024-05, Vol.295 (5), p.583-598

2024

Link zum Volltext

Verfügbarkeit prüfen

Current level of evidence for improvement of antidepressant efficacy and tolerability by pharmacogenomic-guided treatment: A Systematic review and meta-analysis of randomized controlled clinical trials

European neuropsychopharmacology, 2024-04, Vol.81, p.43-52

2024

Link zum Volltext

Verfügbarkeit prüfen

Impact of CYP2C19 Genotype on Escitalopram Exposure and Therapeutic Failure: A Retrospective Study Based on 2,087 Patients

The American journal of psychiatry, 2018-05, Vol.175 (5), p.463-470

2018

Link zum Volltext

Verfügbarkeit prüfen

Evaluation of Current Regulation and Guidelines of Pharmacogenomic Drug Labels: Opportunities for Improvements

Clinical pharmacology and therapeutics, 2020-05, Vol.107 (5), p.1240-1255

2020

Link zum Volltext

Verfügbarkeit prüfen

Impact of NFIB and CYP1A variants on clozapine serum concentration—A retrospective naturalistic cohort study on 526 patients with known smoking habits

Clinical and translational science, 2023-01, Vol.16 (1), p.62-72

2023

Link zum Volltext

Verfügbarkeit prüfen

CYP2E1 in Alcoholic and Non-Alcoholic Liver Injury. Roles of ROS, Reactive Intermediates and Lipid Overload

International journal of molecular sciences, 2021-08, Vol.22 (15), p.8221

2021

Link zum Volltext

Verfügbarkeit prüfen

Pharmacogenomic Biomarkers for Improved Drug Therapy—Recent Progress and Future Developments

The AAPS journal, 2017-11, Vol.20 (1), p.4-4, Article 4

2017

Link zum Volltext

Verfügbarkeit prüfen

Genetic variation in the human cytochrome P450 supergene family

Pharmacogenetics and genomics, 2015-12, Vol.25 (12), p.584-594

2015

Link zum Volltext

Verfügbarkeit prüfen

Novel genetic and epigenetic factors of importance for inter-individual differences in drug disposition, response and toxicity

Pharmacology & therapeutics (Oxford), 2019-05, Vol.197, p.122-152

2019

Link zum Volltext

Verfügbarkeit prüfen

Prediction of Drug-Induced Hepatotoxicity Using Long-Term Stable Primary Hepatic 3D Spheroid Cultures in Chemically Defined Conditions

Toxicological sciences, 2018-06, Vol.163 (2), p.655-665

2018

Link zum Volltext

Verfügbarkeit prüfen

Epigenetic mechanisms of importance for drug treatment

Trends in pharmacological sciences (Regular ed.), 2014-08, Vol.35 (8), p.384-396

2014

Link zum Volltext

Verfügbarkeit prüfen

Pharmacogenomic Biomarkers for Prediction of Severe Adverse Drug Reactions

The New England journal of medicine, 2008-02, Vol.358 (6), p.637-639

Ingelman-Sundberg, Magnus

2008

Link zum Volltext

Verfügbarkeit prüfen

1 – 25 von 520

Suche als RSS-Feed

Suchergebnisse filtern

Filter anzeigen

Nur zeigen

Geprüft (Peer-Review)
(484)
Mit Volltextzugriff
(426)

Publikationsform

Sprache

Englisch
(519)
Japanisch
(154)
Norwegisch
(3)
Deutsch
(1)

Erscheinungsjahr

n.n

Thema

Science & Technology
(401)
Life Sciences & Biomedicine
(389)
Medicin Och Hälsovetenskap
(351)
Humans
(281)
Animals
(186)
Pharmacology & Pharmacy
(168)
Biological And Medical Sciences
(145)
Male
(142)
Rats
(108)
Medical Sciences
(102)
Biochemistry & Molecular Biology
(100)
Cytochrome P-450 Enzyme System - Metabolism
(91)
Cytochrome P-450 Enzyme System - Genetics
(77)
Female
(74)
Toxicology
(71)
Cytochrome P450
(70)
Pharmacology
(59)
Biochemistry
(56)
Genotype
(53)
Microsomes, Liver - Enzymology
(53)

15 weitere anzeigen...

Weniger anzeigen...

Zeitschrift / Serie

5 weitere anzeigen...

Weniger anzeigen...

Neu hinzugefügt

... seit 7 Tagen
(1)
... seit 90 Tagen
(6)

Menü

Weitere Dienste

Einstellungen

The Pharmacogene Variation (PharmVar) Consortium: Incorporation of the Human Cytochrome P450 (CYP) Allele Nomenclature Database

Endogenous and xenobiotic metabolic stability of primary human hepatocytes in long‐term 3D spheroid cultures revealed by a combination of targeted and untargeted metabolomics

3D human liver spheroids for translational pharmacology and toxicology

How to Consider Rare Genetic Variants in Personalized Drug Therapy

Development of the PGx‐Passport: A Panel of Actionable Germline Genetic Variants for Pre‐Emptive Pharmacogenetic Testing

Massive rearrangements of cellular MicroRNA signatures are key drivers of hepatocyte dedifferentiation

Transcriptional and post-transcriptional regulation of the pregnane X receptor: a rationale for interindividual variability in drug metabolism

A 3D Cell Culture Model Identifies Wnt/β‐Catenin Mediated Inhibition of p53 as a Critical Step during Human Hepatocyte Regeneration

Evidence-based selection of training compounds for use in the mechanism-based integrated prediction of drug-induced liver injury in man

Impact of the novel CYP2C:TG haplotype and CYP2B6 variants on sertraline exposure in a large patient population

Effect of the NFIB rs28379954 T>C polymorphism on CYP2D6‐catalyzed metabolism of solanidine

Increased omeprazole metabolism in carriers of the CYP2C1917 allele; a pharmacokinetic study in healthy volunteers

The humanised CYP2C19 transgenic mouse exhibits cerebellar atrophy and movement impairment reminiscent of ataxia

Precision medicine in cardiovascular therapeutics: Evaluating the role of pharmacogenetic analysis prior to drug treatment

Current level of evidence for improvement of antidepressant efficacy and tolerability by pharmacogenomic-guided treatment: A Systematic review and meta-analysis of randomized controlled clinical trials

Impact of CYP2C19 Genotype on Escitalopram Exposure and Therapeutic Failure: A Retrospective Study Based on 2,087 Patients

Evaluation of Current Regulation and Guidelines of Pharmacogenomic Drug Labels: Opportunities for Improvements

Impact of NFIB and CYP1A variants on clozapine serum concentration—A retrospective naturalistic cohort study on 526 patients with known smoking habits

CYP2E1 in Alcoholic and Non-Alcoholic Liver Injury. Roles of ROS, Reactive Intermediates and Lipid Overload

Pharmacogenomic Biomarkers for Improved Drug Therapy—Recent Progress and Future Developments

Genetic variation in the human cytochrome P450 supergene family

Novel genetic and epigenetic factors of importance for inter-individual differences in drug disposition, response and toxicity

Prediction of Drug-Induced Hepatotoxicity Using Long-Term Stable Primary Hepatic 3D Spheroid Cultures in Chemically Defined Conditions

Epigenetic mechanisms of importance for drug treatment

Pharmacogenomic Biomarkers for Prediction of Severe Adverse Drug Reactions

Suchergebnisse filtern