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Identification of a Novel and Selective Series of Itk Inhibitors via a Template-Hopping Strategy

ACS medicinal chemistry letters, 2013-10, Vol.4 (10), p.948-952

2013

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The discovery of potent and long-acting oral factor Xa inhibitors with tetrahydroisoquinoline and benzazepine P4 motifs

Bioorganic & medicinal chemistry letters, 2011-03, Vol.21 (6), p.1588-1592

2011

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Structure and property based design of factor Xa inhibitors: Pyrrolidin-2-ones with aminoindane and phenylpyrrolidine P4 motifs

Bioorganic & medicinal chemistry letters, 2011-03, Vol.21 (6), p.1582-1587

2011

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Structure and property based design of factor Xa inhibitors: pyrrolidin-2-ones with monoaryl P4 motifs

Bioorganic & medicinal chemistry letters, 2010-01, Vol.20 (2), p.618-622

2010

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(1 H-Imidazo[4,5- c]pyridin-2-yl)-1,2,5-oxadiazol-3-ylamine derivatives: A novel class of potent MSK-1-inhibitors

Bioorganic & medicinal chemistry letters, 2005-07, Vol.15 (14), p.3402-3406

2005

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Investigation of the importance of nitrogen substituents in a N–P chiral ligand for enantioselective allylic alkylation

Tetrahedron: asymmetry, , Vol.12 (6), p.923-935

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The design of 8,8-Dimethyl[1,6]naphthyridines as potential anticonvulsant agents

Bioorganic & medicinal chemistry letters, 2003-05, Vol.13 (10), p.1627-1629

2003

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Some novel electron transfer mediated cascade ring-opening reactions of bicyclo[4.1.0]ketones

Tetrahedron, 1996-08, Vol.52 (35), p.11421-11444

1996

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Corrigendum to “(1H-Imidazo[4,5-c]pyridin-2-yl)-1,2,5-oxadiazol-3-ylamine derivatives: A novel class of potent MSK-1-inhibitors” [Bioorg. Med. Chem. Lett. 15 (2005) 3402–3406]

Bioorganic & medicinal chemistry letters, 2015-03, Vol.25 (5), p.1151-1151

2015

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A stereoselective synthesis of 3-substituted hexahydroindeno[2,1-b]pyrroles via an intramolecular azomethine ylide cycloaddition

Tetrahedron, 1998-12, Vol.54 (49), p.14905-14912

1998

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Dramatic reversal of enantioselection in a palladium catalysed allylic substitution by choice of nitrogen substituents in a N–P chiral ligand

Tetrahedron: asymmetry, 1999-07, Vol.10 (15), p.2829-2832

1999

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An Efficient Synthesis of Lactacystin β‐Lactone

Angewandte Chemie, 2004-04, Vol.116 (17), p.2343-2346

2004

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PREPARATION OF 1,7-DISUBSTITUTED-1,2,3,4-TETRAHYDROISOQUINOLINES

Synthetic communications, 2002-01, Vol.32 (16), p.2555-2563

2002

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A FACILE SYNTHESIS OF THE 3-AMINO-5,6,7,8-TETRAHYDRO[1,6]NAPHTHYRIDINE SYSTEM AND SOME ALKYLATED AND POLYCYCLIC HOMOLOGUES

Synthetic communications, 2001-01, Vol.31 (5), p.787-797

2001

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SB-431542 Is a Potent and Specific Inhibitor of Transforming Growth Factor-Î² Superfamily Type I Activin Receptor-Like Kinase (ALK) Receptors ALK4, ALK5, and ALK7

Molecular pharmacology, 2002-07, Vol.62 (1), p.65

2002

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Characterisation of SB-221420-A : a neuronal Ca2+ and Na+ channel antagonist in experimental models of stroke

European journal of pharmacology, 2000-08, Vol.401 (3), p.419-428

2000

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Characterisation of SB-221420-A - a neuronal Ca(2+) and Na(+) channel antagonist in experimental models of stroke

European journal of pharmacology, 2000-08, Vol.401 (3), p.419-428

2000

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Evaluation of a series of anticonvulsant 1,2,3,4-tetrahydroisoquinolinyl-benzamides

Bioorganic & medicinal chemistry, 2000-08, Vol.8 (8), p.2085-2094

2000

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Identification of novel inhibitors of the transforming growth factor beta1 (TGF-beta1) type 1 receptor (ALK5)

Journal of medicinal chemistry, 2002-02, Vol.45 (5), p.999-1001

2002

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Identification of a series of 1,2,3,4-tetrahydroisoquinolinyl- benzamides with potential anticonvulsant activity

Bioorganic & medicinal chemistry letters, 1998-10, Vol.8 (20), p.2903-2906

1998

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Construction of bicyclic systems via a tandem free radical cyclopropylcarbinyl rearrangement-cyclisation strategy

Tetrahedron, 1992, Vol.48 (37), p.8031-8052

1992

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An Efficient Synthesis of Lactacystin β-Lactone

Angewandte Chemie, 2004-04, Vol.116 (17), p.2343-2346

2004

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Characterisation of SB-221420-A — a neuronal Ca 2+ and Na + channel antagonist in experimental models of stroke

European journal of pharmacology, 2000, Vol.401 (3), p.419-428

2000

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Origins of the regioselectivity of cyclopropylcarbinyl ring opening reactions in bicyclo [n.1.0] systems

Journal of the Chemical Society. Chemical communications, 1992 (13), p.942-944

1992

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ChemInform Abstract: Phosphinates as New Electrophilic Partners for Cross-Coupling Reactions

ChemInform, 2009-03, Vol.40 (11), p.no-no

2009

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Identification of a Novel and Selective Series of Itk Inhibitors via a Template-Hopping Strategy

The discovery of potent and long-acting oral factor Xa inhibitors with tetrahydroisoquinoline and benzazepine P4 motifs

Structure and property based design of factor Xa inhibitors: Pyrrolidin-2-ones with aminoindane and phenylpyrrolidine P4 motifs

Structure and property based design of factor Xa inhibitors: pyrrolidin-2-ones with monoaryl P4 motifs

(1 H-Imidazo[4,5- c]pyridin-2-yl)-1,2,5-oxadiazol-3-ylamine derivatives: A novel class of potent MSK-1-inhibitors

Investigation of the importance of nitrogen substituents in a N–P chiral ligand for enantioselective allylic alkylation

The design of 8,8-Dimethyl[1,6]naphthyridines as potential anticonvulsant agents

Some novel electron transfer mediated cascade ring-opening reactions of bicyclo[4.1.0]ketones

Corrigendum to “(1H-Imidazo[4,5-c]pyridin-2-yl)-1,2,5-oxadiazol-3-ylamine derivatives: A novel class of potent MSK-1-inhibitors” [Bioorg. Med. Chem. Lett. 15 (2005) 3402–3406]

A stereoselective synthesis of 3-substituted hexahydroindeno[2,1-b]pyrroles via an intramolecular azomethine ylide cycloaddition

Dramatic reversal of enantioselection in a palladium catalysed allylic substitution by choice of nitrogen substituents in a N–P chiral ligand

An Efficient Synthesis of Lactacystin β‐Lactone

PREPARATION OF 1,7-DISUBSTITUTED-1,2,3,4-TETRAHYDROISOQUINOLINES

A FACILE SYNTHESIS OF THE 3-AMINO-5,6,7,8-TETRAHYDRO[1,6]NAPHTHYRIDINE SYSTEM AND SOME ALKYLATED AND POLYCYCLIC HOMOLOGUES

SB-431542 Is a Potent and Specific Inhibitor of Transforming Growth Factor-Î² Superfamily Type I Activin Receptor-Like Kinase (ALK) Receptors ALK4, ALK5, and ALK7

Characterisation of SB-221420-A : a neuronal Ca2+ and Na+ channel antagonist in experimental models of stroke

Characterisation of SB-221420-A - a neuronal Ca(2+) and Na(+) channel antagonist in experimental models of stroke

Evaluation of a series of anticonvulsant 1,2,3,4-tetrahydroisoquinolinyl-benzamides

Identification of novel inhibitors of the transforming growth factor beta1 (TGF-beta1) type 1 receptor (ALK5)

Identification of a series of 1,2,3,4-tetrahydroisoquinolinyl- benzamides with potential anticonvulsant activity

Construction of bicyclic systems via a tandem free radical cyclopropylcarbinyl rearrangement-cyclisation strategy

An Efficient Synthesis of Lactacystin β-Lactone

Characterisation of SB-221420-A — a neuronal Ca 2+ and Na + channel antagonist in experimental models of stroke

Origins of the regioselectivity of cyclopropylcarbinyl ring opening reactions in bicyclo [n.1.0] systems

ChemInform Abstract: Phosphinates as New Electrophilic Partners for Cross-Coupling Reactions

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