UB Paderborn / Katalog / Suche / in CDI

1 – 25 von 73

Sortiert nach

A two-faced selectivity solution to target SMARCA2 for cancer therapy

Nature communications, 2023-01, Vol.14 (1), p.515-515, Article 515

2023

Link zum Volltext

Verfügbarkeit prüfen

PROTAC-Mediated Degradation of Bruton’s Tyrosine Kinase Is Inhibited by Covalent Binding

ACS chemical biology, 2019-03, Vol.14 (3), p.342-347

2019

Link zum Volltext

Verfügbarkeit prüfen

Extended pharmacodynamic responses observed upon PROTAC-mediated degradation of RIPK2

Communications biology, 2020-03, Vol.3 (1), p.140, Article 140

2020

Link zum Volltext

Verfügbarkeit prüfen

A caged E3 ligase ligand for PROTAC-mediated protein degradation with light

Chemical communications (Cambridge, England), 2020-05, Vol.56 (41), p.5532-5535

2020

Link zum Volltext

Verfügbarkeit prüfen

HaloPROTACS: Use of Small Molecule PROTACs to Induce Degradation of HaloTag Fusion Proteins

ACS chemical biology, 2015-08, Vol.10 (8), p.1831-1837

2015

Link zum Volltext

Verfügbarkeit prüfen

The therapeutic potential of PROTACs

Expert opinion on therapeutic patents, 2021, Vol.31 (1), p.1-24

2021

Link zum Volltext

Verfügbarkeit prüfen

Identification of Novel Inhibitors of the Transforming Growth Factor β1 (TGF-β1) Type 1 Receptor (ALK5)

Journal of medicinal chemistry, 2002-02, Vol.45 (5), p.999-1001

2002

Link zum Volltext

Verfügbarkeit prüfen

Discovery and Characterisation of Highly Cooperative FAK‐Degrading PROTACs

Angewandte Chemie (International ed.), 2021-10, Vol.60 (43), p.23327-23334

International ed. in English, 2021

Link zum Volltext

Verfügbarkeit prüfen

Structural Insights into PROTAC-Mediated Degradation of Bcl-xL

ACS chemical biology, 2020-09, Vol.15 (9), p.2316-2323

2020

Link zum Volltext

Verfügbarkeit prüfen

Optimization of a Series of RIPK2 PROTACs

Journal of medicinal chemistry, 2021-09, Vol.64 (17), p.12978-13003

2021

Link zum Volltext

Verfügbarkeit prüfen

Challenges and opportunities for in vivo PROTAC delivery

Future medicinal chemistry, 2022-01, Vol.14 (3), p.119

2022

Link zum Volltext

Verfügbarkeit prüfen

Light-mediated multi-target protein degradation using arylazopyrazole photoswitchable PROTACs (AP-PROTACs)

Chemical communications (Cambridge, England), 2022-09, Vol.58 (78), p.1933-1936

2022

Link zum Volltext

Verfügbarkeit prüfen

Structure-Guided Design and Optimization of Covalent VHL-Targeted Sulfonyl Fluoride PROTACs

Journal of medicinal chemistry, 2024-03, Vol.67 (6), p.4641-4654

2024

Link zum Volltext

Verfügbarkeit prüfen

Integrated Direct-to-Biology Platform for the Nanoscale Synthesis and Biological Evaluation of PROTACs

Journal of medicinal chemistry, 2023-11, Vol.66 (22), p.15437-15452

2023

Link zum Volltext

Verfügbarkeit prüfen

Activating mechanosensitive channels embedded in droplet interface bilayers using membrane asymmetry

Chemical science (Cambridge), 2021-02, Vol.12 (6), p.2138-2145

2021

Link zum Volltext

Verfügbarkeit prüfen

UV-DIB: label-free permeability determination using droplet interface bilayers

Lab on a chip, 2022-03, Vol.22 (5), p.972-985

2022

Link zum Volltext

Verfügbarkeit prüfen

SB-431542 is a potent and specific inhibitor of transforming growth factor-beta superfamily type I activin receptor-like kinase (ALK) receptors ALK4, ALK5, and ALK7

Molecular pharmacology, 2002-07, Vol.62 (1), p.65-74

2002

Link zum Volltext

Verfügbarkeit prüfen

Discovery of Novel Irreversible Inhibitors of Interleukin (IL)-2-inducible Tyrosine Kinase (Itk) by Targeting Cysteine 442 in the ATP Pocket

The Journal of biological chemistry, 2013-09, Vol.288 (39), p.28195-28206

2013

Link zum Volltext

Verfügbarkeit prüfen

One-pot synthesis of benzothiazolines and napthathiazolines via cascade ortho-lithiation, cyclisation and elimination of N-arylsulfonyl lactams

Organic & biomolecular chemistry, 2007-01, Vol.5 (21), p.3472-3476

2007

Link zum Volltext

Verfügbarkeit prüfen

Discovery and Characterisation of Highly Cooperative FAK‐Degrading PROTACs

Angewandte Chemie, 2021-10, Vol.133 (43), p.23515-23522

2021

Link zum Volltext

Verfügbarkeit prüfen

An Efficient Synthesis of Lactacystin β-Lactone

Angewandte Chemie (International ed.), 2004-04, Vol.43 (17), p.2293-2296

2004

Link zum Volltext

Verfügbarkeit prüfen

Utility of the Ammonia-Free Birch Reduction of Electron-Deficient Pyrroles: Total Synthesis of the 20S Proteasome Inhibitor, clasto-Lactacystin β-Lactone

Chemistry : a European journal, 2005-07, Vol.11 (14), p.4227-4238

2005

Link zum Volltext

Verfügbarkeit prüfen

Phosphinates as new electrophilic partners for cross-coupling reactions

Organic & biomolecular chemistry, 2008-01, Vol.6 (21), p.4053-4058

2008

Link zum Volltext

Verfügbarkeit prüfen

Identification of a Novel and Selective Series of Itk Inhibitors via a Template-Hopping Strategy

ACS medicinal chemistry letters, 2013-10, Vol.4 (10), p.948-952

2013

Link zum Volltext

Verfügbarkeit prüfen

1 – 25 von 73

Suche als RSS-Feed

Aktive Filter

KollektionOxford Journals

Suchergebnisse filtern

Filter anzeigen

Nur zeigen

Geprüft (Peer-Review)
(65)
Mit Volltextzugriff
(65)

Publikationsform

Artikel
(72)
Bücher
(1)

Sprache

Erscheinungsjahr

n.n

Thema

15 weitere anzeigen...

Weniger anzeigen...

Zeitschrift / Serie

5 weitere anzeigen...

Weniger anzeigen...

Neu hinzugefügt

... seit 30 Tagen
(1)
... seit 90 Tagen
(2)

Menü

Weitere Dienste

Einstellungen

A two-faced selectivity solution to target SMARCA2 for cancer therapy

PROTAC-Mediated Degradation of Bruton’s Tyrosine Kinase Is Inhibited by Covalent Binding

Extended pharmacodynamic responses observed upon PROTAC-mediated degradation of RIPK2

A caged E3 ligase ligand for PROTAC-mediated protein degradation with light

Catalytic in vivo protein knockdown by small-molecule PROTACs

HaloPROTACS: Use of Small Molecule PROTACs to Induce Degradation of HaloTag Fusion Proteins

The therapeutic potential of PROTACs

Identification of Novel Inhibitors of the Transforming Growth Factor β1 (TGF-β1) Type 1 Receptor (ALK5)

Discovery and Characterisation of Highly Cooperative FAK‐Degrading PROTACs

Structural Insights into PROTAC-Mediated Degradation of Bcl-xL

Optimization of a Series of RIPK2 PROTACs

Challenges and opportunities for in vivo PROTAC delivery

Light-mediated multi-target protein degradation using arylazopyrazole photoswitchable PROTACs (AP-PROTACs)

Structure-Guided Design and Optimization of Covalent VHL-Targeted Sulfonyl Fluoride PROTACs

Integrated Direct-to-Biology Platform for the Nanoscale Synthesis and Biological Evaluation of PROTACs

Activating mechanosensitive channels embedded in droplet interface bilayers using membrane asymmetry

UV-DIB: label-free permeability determination using droplet interface bilayers

SB-431542 is a potent and specific inhibitor of transforming growth factor-beta superfamily type I activin receptor-like kinase (ALK) receptors ALK4, ALK5, and ALK7

Discovery of Novel Irreversible Inhibitors of Interleukin (IL)-2-inducible Tyrosine Kinase (Itk) by Targeting Cysteine 442 in the ATP Pocket

One-pot synthesis of benzothiazolines and napthathiazolines via cascade ortho-lithiation, cyclisation and elimination of N-arylsulfonyl lactams

Discovery and Characterisation of Highly Cooperative FAK‐Degrading PROTACs

An Efficient Synthesis of Lactacystin β-Lactone

Utility of the Ammonia-Free Birch Reduction of Electron-Deficient Pyrroles: Total Synthesis of the 20S Proteasome Inhibitor, clasto-Lactacystin β-Lactone

Phosphinates as new electrophilic partners for cross-coupling reactions

Identification of a Novel and Selective Series of Itk Inhibitors via a Template-Hopping Strategy

Aktive Filter

Suchergebnisse filtern