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Automated Structure- and Sequence-Based Design of Proteins for High Bacterial Expression and Stability

Molecular cell, 2016-07, Vol.63 (2), p.337-346

2016

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Automated Design of Efficient and Functionally Diverse Enzyme Repertoires

Molecular cell, 2018-10, Vol.72 (1), p.178-186.e5

2018

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Directed evolution of hydrolases for prevention of G-type nerve agent intoxication

Nature chemical biology, 2011-02, Vol.7 (2), p.120

2011

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Computational redesign of a mononuclear zinc metalloenzyme for organophosphate hydrolysis

Nature chemical biology, 2012-02, Vol.8 (3), p.294

2012

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Overcoming an optimization plateau in the directed evolution of highly efficient nerve agent bioscavengers

Protein engineering, design and selection, 2017-04, Vol.30 (4), p.333-345

2017

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Potential role of phenotypic mutations in the evolution of protein expression and stability

Proceedings of the National Academy of Sciences - PNAS, 2009-04, Vol.106 (15), p.6197-6202

2009

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A new post-intoxication treatment of paraoxon and parathion poisonings using an evolved PON1 variant and recombinant GOT1

Chemico-biological interactions, 2016-11, Vol.259 (Pt B), p.242-251

2016

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Automated Structure- and Sequence-Based Design of Proteins for High Bacterial Expression and Stability

Molecular cell, 2018-04, Vol.70 (2), p.380-380

2018

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Catalytic bioscavengers as countermeasures against organophosphate nerve agents

Chemico-biological interactions, 2018-08, Vol.292, p.50-64

2018

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Enzyme engineering: reaching the maximal catalytic efficiency peak

Current opinion in structural biology, 2017-12, Vol.47, p.140-150

2017

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Corrigendum to “Catalytic bioscavengers as countermeasures against organophosphate nerve agents”, [Chem. Biol. Interact. 292 (2018) 50–64]

Chemico-biological interactions, 2018-09, Vol.293, p.152-152

2018

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Directed enzyme evolution: beyond the low-hanging fruit

Current opinion in structural biology, 2012-08, Vol.22 (4), p.406-412

2012

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Analysis of Strand Transfer and Template Switching Mechanisms of DNA Gap Repair by Homologous Recombination in Escherichia coli: Predominance of Strand Transfer

Journal of molecular biology, 2008-09, Vol.381 (4), p.803-809

2008

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Designed High-Redox Potential Laccases Exhibit High Functional Diversity

ACS catalysis, 2022-11, Vol.12 (21), p.13164-13173

2022

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Design and in vitro realization of carbon-conserving photorespiration

Proceedings of the National Academy of Sciences - PNAS, 2018-12, Vol.115 (49), p.E11455-E11464

2018

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Designer Liposomic Nanocarriers Are Effective Biofilm Eradicators

ACS nano, 2022-10, Vol.16 (10), p.15792-15804

2022

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Plasmid-Encoded MucB Protein Is a DNA Polymerase (pol RI) Specialized for Lesion Bypass in the Presence of MucA′, RecA, and SSB

Proceedings of the National Academy of Sciences - PNAS, 2000-10, Vol.97 (21), p.11227-11231

2000

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Stable Mammalian Serum Albumins Designed for Bacterial Expression

Journal of molecular biology, 2023-09, Vol.435 (17), p.168191-168191, Article 168191

2023

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Identification and characterization of the key enzyme in the biosynthesis of the neurotoxin β-ODAP in grass pea

The Journal of biological chemistry, 2022-05, Vol.298 (5), p.101806-101806, Article 101806

2022

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Carbohydrate dynamics in Populus trees under drought: An expression atlas of genes related to sensing, translocation, and metabolism across organs

Physiologia plantarum, 2023-08, Vol.175 (5), p.e14001-e14001

2023

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The identification and characterization of an oxalyl-CoA synthetase from grass pea ( L.)

RSC chemical biology, 2022-03, Vol.3 (3), p.32-333

2022

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Post-exposure treatment of VX poisoned guinea pigs with the engineered phosphotriesterase mutant C23: A proof-of-concept study

Toxicology letters, 2014-11, Vol.231 (1), p.45-54

2014

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Catalytic efficiencies of directly evolved phosphotriesterase variants with structurally different organophosphorus compounds in vitro

Archives of toxicology, 2016-11, Vol.90 (11), p.2711-2724

2016

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In vitro evaluation of the catalytic activity of paraoxonases and phosphotriesterases predicts the enzyme circulatory levels required for in vivo protection against organophosphate intoxications

Chemico-biological interactions, 2016-11, Vol.259 (Pt B), p.252-256

2016

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Efficacy of the rePON1 mutant IIG1 to prevent cyclosarin toxicity in vivo and to detoxify structurally different nerve agents in vitro

Archives of toxicology, 2014-06, Vol.88 (6), p.1257-1266

2014

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Automated Structure- and Sequence-Based Design of Proteins for High Bacterial Expression and Stability

Automated Design of Efficient and Functionally Diverse Enzyme Repertoires

Directed evolution of hydrolases for prevention of G-type nerve agent intoxication

Computational redesign of a mononuclear zinc metalloenzyme for organophosphate hydrolysis

Overcoming an optimization plateau in the directed evolution of highly efficient nerve agent bioscavengers

Potential role of phenotypic mutations in the evolution of protein expression and stability

A new post-intoxication treatment of paraoxon and parathion poisonings using an evolved PON1 variant and recombinant GOT1

Automated Structure- and Sequence-Based Design of Proteins for High Bacterial Expression and Stability

Catalytic bioscavengers as countermeasures against organophosphate nerve agents

Enzyme engineering: reaching the maximal catalytic efficiency peak

Corrigendum to “Catalytic bioscavengers as countermeasures against organophosphate nerve agents”, [Chem. Biol. Interact. 292 (2018) 50–64]

Directed enzyme evolution: beyond the low-hanging fruit

Analysis of Strand Transfer and Template Switching Mechanisms of DNA Gap Repair by Homologous Recombination in Escherichia coli: Predominance of Strand Transfer

Designed High-Redox Potential Laccases Exhibit High Functional Diversity

Design and in vitro realization of carbon-conserving photorespiration

Designer Liposomic Nanocarriers Are Effective Biofilm Eradicators

Plasmid-Encoded MucB Protein Is a DNA Polymerase (pol RI) Specialized for Lesion Bypass in the Presence of MucA′, RecA, and SSB

Stable Mammalian Serum Albumins Designed for Bacterial Expression

Identification and characterization of the key enzyme in the biosynthesis of the neurotoxin β-ODAP in grass pea

Carbohydrate dynamics in Populus trees under drought: An expression atlas of genes related to sensing, translocation, and metabolism across organs

The identification and characterization of an oxalyl-CoA synthetase from grass pea ( L.)

Post-exposure treatment of VX poisoned guinea pigs with the engineered phosphotriesterase mutant C23: A proof-of-concept study

Catalytic efficiencies of directly evolved phosphotriesterase variants with structurally different organophosphorus compounds in vitro

In vitro evaluation of the catalytic activity of paraoxonases and phosphotriesterases predicts the enzyme circulatory levels required for in vivo protection against organophosphate intoxications

Efficacy of the rePON1 mutant IIG1 to prevent cyclosarin toxicity in vivo and to detoxify structurally different nerve agents in vitro

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