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Vesicular Glutamate Transporters 1 and 2 Target to Functionally Distinct Synaptic Release Sites

Science (American Association for the Advancement of Science), 2004-06, Vol.304 (5678), p.1815-1819

2004

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Transcriptional characterization of iPSC-derived microglia as a model for therapeutic development in neurodegeneration

Scientific reports, 2024-01, Vol.14 (1), p.2153-2153, Article 2153

2024

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VGLUTs define subsets of excitatory neurons and suggest novel roles for glutamate

Trends in neurosciences (Regular ed.), 2004-02, Vol.27 (2), p.98-103

2004

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Uptake of Glutamate into Synaptic Vesicles by an Inorganic Phosphate Transporter

Science (American Association for the Advancement of Science), 2000-08, Vol.289 (5481), p.957-960

2000

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The Identification of Vesicular Glutamate Transporter 3 Suggests Novel Modes of Signaling by Glutamate

Proceedings of the National Academy of Sciences - PNAS, 2002-10, Vol.99 (22), p.14488-14493

2002

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From Fragment Screening to In Vivo Efficacy: Optimization of a Series of 2-Aminoquinolines as Potent Inhibitors of Beta-Site Amyloid Precursor Protein Cleaving Enzyme 1 (BACE1)

Journal of medicinal chemistry, 2011-08, Vol.54 (16), p.5836-5857

2011

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Expression of the vesicular glutamate transporters during development indicates the widespread corelease of multiple neurotransmitters

Journal of comparative neurology (1911), 2004-12, Vol.480 (3), p.264-280

2004

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The Expression of Vesicular Glutamate Transporters Defines Two Classes of Excitatory Synapse

Neuron (Cambridge, Mass.), 2001-08, Vol.31 (2), p.247-260

2001

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Structure- and Property-Based Design of Aminooxazoline Xanthenes as Selective, Orally Efficacious, and CNS Penetrable BACE Inhibitors for the Treatment of Alzheimer’s Disease

Journal of medicinal chemistry, 2012-11, Vol.55 (21), p.9156-9169

2012

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Author Correction: Transcriptional characterization of iPSC-derived microglia as a model for therapeutic development in neurodegeneration

Scientific reports, 2024-04, Vol.14 (1), p.9346-9346

2024

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Distribution of vesicular glutamate transporters 1 and 2 in the rat spinal cord, with a note on the spinocervical tract

Journal of comparative neurology (1911), 2006-08, Vol.497 (5), p.683-701

2006

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Vesicular glutamate transporter 3 expression identifies glutamatergic amacrine cells in the rodent retina

Journal of comparative neurology (1911), 2004-09, Vol.477 (4), p.386-398

2004

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Lead Optimization and Modulation of hERG Activity in a Series of Aminooxazoline Xanthene β‑Site Amyloid Precursor Protein Cleaving Enzyme (BACE1) Inhibitors

Journal of medicinal chemistry, 2014-12, Vol.57 (23), p.9796-9810

2014

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Vesicular Glutamate Transporter 1 Is Required for Photoreceptor Synaptic Signaling But Not For Intrinsic Visual Functions

The Journal of neuroscience, 2007-07, Vol.27 (27), p.7245-7255

2007

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Sulfonamides as Selective NaV1.7 Inhibitors: Optimizing Potency and Pharmacokinetics to Enable in Vivo Target Engagement

ACS medicinal chemistry letters, 2016-12, Vol.7 (12), p.1062-1067

2016

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Discovery of Potent, Orally Bioavailable Phthalazinone Bradykinin B1 Receptor Antagonists

Journal of medicinal chemistry, 2011-10, Vol.54 (20), p.7232-7246

2011

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Discovery and Optimization of a Novel Series of N-Arylamide Oxadiazoles as Potent, Highly Selective and Orally Bioavailable Cannabinoid Receptor 2 (CB2) Agonists

Journal of medicinal chemistry, 2008-08, Vol.51 (16), p.5019-5034

2008

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Endocannabinoid-Independent Retrograde Signaling at Inhibitory Synapses in Layer 2/3 of Neocortex: Involvement of Vesicular Glutamate Transporter 3

The Journal of neuroscience, 2004-05, Vol.24 (21), p.4978-4988

2004

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Complementary distribution of vesicular glutamate transporters 1 and 2 in the nucleus accumbens of rat: Relationship to calretinin-containing extrinsic innervation and calbindin-immunoreactive neurons

Journal of comparative neurology (1911), 2003-10, Vol.465 (1), p.1-10

2003

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An Orally Available BACE1 Inhibitor That Affords Robust CNS Aβ Reduction without Cardiovascular Liabilities

ACS medicinal chemistry letters, 2015-02, Vol.6 (2), p.210-215

2015

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Cloning and expression of a functional serotonin transporter from rat brain

Nature (London), 1991-11, Vol.354 (6348), p.66-70

1991

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Molecular cloning and expression of the gene for a human D1 dopamine receptor

Nature (London), 1990-09, Vol.347 (6288), p.72-76

1990

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Discovery of α-amidosulfones as potent and selective agonists of CB2 : Synthesis, SAR, and pharmacokinetic properties

Bioorganic & medicinal chemistry letters, 2009, Vol.19 (1), p.31-35

2009

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Sulfonamides as Selective NaV1.7 Inhibitors: Optimizing Potency, Pharmacokinetics, and Metabolic Properties to Obtain Atropisomeric Quinolinone (AM-0466) that Affords Robust in Vivo Activity

Journal of medicinal chemistry, 2017-07, Vol.60 (14), p.5990-6017

2017

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Vesicular Glutamate Transporters 1 and 2 Target to Functionally Distinct Synaptic Release Sites

Transcriptional characterization of iPSC-derived microglia as a model for therapeutic development in neurodegeneration

VGLUTs define subsets of excitatory neurons and suggest novel roles for glutamate

Uptake of Glutamate into Synaptic Vesicles by an Inorganic Phosphate Transporter

The Identification of Vesicular Glutamate Transporter 3 Suggests Novel Modes of Signaling by Glutamate

From Fragment Screening to In Vivo Efficacy: Optimization of a Series of 2-Aminoquinolines as Potent Inhibitors of Beta-Site Amyloid Precursor Protein Cleaving Enzyme 1 (BACE1)

Expression of the vesicular glutamate transporters during development indicates the widespread corelease of multiple neurotransmitters

The Expression of Vesicular Glutamate Transporters Defines Two Classes of Excitatory Synapse

Structure- and Property-Based Design of Aminooxazoline Xanthenes as Selective, Orally Efficacious, and CNS Penetrable BACE Inhibitors for the Treatment of Alzheimer’s Disease

Author Correction: Transcriptional characterization of iPSC-derived microglia as a model for therapeutic development in neurodegeneration

Distribution of vesicular glutamate transporters 1 and 2 in the rat spinal cord, with a note on the spinocervical tract

Vesicular glutamate transporter 3 expression identifies glutamatergic amacrine cells in the rodent retina

Lead Optimization and Modulation of hERG Activity in a Series of Aminooxazoline Xanthene β‑Site Amyloid Precursor Protein Cleaving Enzyme (BACE1) Inhibitors

Vesicular Glutamate Transporter 1 Is Required for Photoreceptor Synaptic Signaling But Not For Intrinsic Visual Functions

Sulfonamides as Selective NaV1.7 Inhibitors: Optimizing Potency and Pharmacokinetics to Enable in Vivo Target Engagement

Discovery of Potent, Orally Bioavailable Phthalazinone Bradykinin B1 Receptor Antagonists

Discovery and Optimization of a Novel Series of N-Arylamide Oxadiazoles as Potent, Highly Selective and Orally Bioavailable Cannabinoid Receptor 2 (CB2) Agonists

Development of 2-aminooxazoline 3-azaxanthenes as orally efficacious β-secretase inhibitors for the potential treatment of Alzheimer’s disease

Endocannabinoid-Independent Retrograde Signaling at Inhibitory Synapses in Layer 2/3 of Neocortex: Involvement of Vesicular Glutamate Transporter 3

Complementary distribution of vesicular glutamate transporters 1 and 2 in the nucleus accumbens of rat: Relationship to calretinin-containing extrinsic innervation and calbindin-immunoreactive neurons

An Orally Available BACE1 Inhibitor That Affords Robust CNS Aβ Reduction without Cardiovascular Liabilities

Cloning and expression of a functional serotonin transporter from rat brain

Molecular cloning and expression of the gene for a human D1 dopamine receptor

Discovery of α-amidosulfones as potent and selective agonists of CB2 : Synthesis, SAR, and pharmacokinetic properties

Sulfonamides as Selective NaV1.7 Inhibitors: Optimizing Potency, Pharmacokinetics, and Metabolic Properties to Obtain Atropisomeric Quinolinone (AM-0466) that Affords Robust in Vivo Activity

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