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Nonhuman primate models of human viral infections

Nature reviews. Immunology, 2018-06, Vol.18 (6), p.390

2018

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Pathobiology of HIV/SIV-associated changes in secondary lymphoid tissues

Immunological reviews, 2013-07, Vol.254 (1), p.65-77

Estes, Jacob D.

2013

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Increased intestinal permeability correlates with sigmoid mucosa alpha-synuclein staining and endotoxin exposure markers in early Parkinson's disease

PloS one, 2011-12, Vol.6 (12), p.e28032-e28032

2011

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Damaged intestinal epithelial integrity linked to microbial translocation in pathogenic simian immunodeficiency virus infections

PLoS pathogens, 2010-08, Vol.6 (8), p.e1001052-e1001052

2010

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B cell follicle sanctuary permits persistent productive simian immunodeficiency virus infection in elite controllers

Nature medicine, 2015-02, Vol.21 (2), p.132-139

2015

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CD8+ Lymphocytes Are Required for Maintaining Viral Suppression in SIV-Infected Macaques Treated with Short-Term Antiretroviral Therapy

Immunity (Cambridge, Mass.), 2016-09, Vol.45 (3), p.656-668

2016

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Tissue Myeloid Cells in SIV-Infected Primates Acquire Viral DNA through Phagocytosis of Infected T Cells

Immunity (Cambridge, Mass.), 2014-09, Vol.41 (3), p.493-502

2014

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In-depth virological and immunological characterization of HIV-1 cure after CCR5Δ32/Δ32 allogeneic hematopoietic stem cell transplantation

Nature medicine, 2023-03, Vol.29 (3), p.583-587

2023

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Treatment with native heterodimeric IL-15 increases cytotoxic lymphocytes and reduces SHIV RNA in lymph nodes

PLoS pathogens, 2018-02, Vol.14 (2), p.e1006902-e1006902

2018

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African green monkeys avoid SIV disease progression by preventing intestinal dysfunction and maintaining mucosal barrier integrity

PLoS pathogens, 2020-03, Vol.16 (3), p.e1008333-e1008333

2020

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Systemic administration of antiretrovirals prior to exposure prevents rectal and intravenous HIV-1 transmission in humanized BLT mice

PloS one, 2010-01, Vol.5 (1), p.e8829-e8829

2010

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Large number of rebounding/founder HIV variants emerge from multifocal infection in lymphatic tissues after treatment interruption

Proceedings of the National Academy of Sciences - PNAS, 2015-03, Vol.112 (10), p.E1126-E1134

2015

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Ad26.COV2.S prevents upregulation of SARS-CoV-2 induced pathways of inflammation and thrombosis in hamsters and rhesus macaques

PLoS pathogens, 2022-04, Vol.18 (4), p.e1009990-e1009990

2022

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Differential impact of transplantation on peripheral and tissue-associated viral reservoirs: Implications for HIV gene therapy

PLoS pathogens, 2018-04, Vol.14 (4), p.e1006956-e1006956

2018

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CD4 depletion in SIV-infected macaques results in macrophage and microglia infection with rapid turnover of infected cells

PLoS pathogens, 2014-10, Vol.10 (10), p.e1004467-e1004467

2014

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Next-generation in situ hybridization approaches to define and quantify HIV and SIV reservoirs in tissue microenvironments

Retrovirology, 2018-01, Vol.15 (1), p.4-4, Article 4

2018

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Intrahepatic CXCL10 is strongly associated with liver fibrosis in HIV-Hepatitis B co-infection

PLoS pathogens, 2020-09, Vol.16 (9), p.e1008744-e1008744

2020

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CD8+ lymphocytes control viral replication in SIVmac239-infected rhesus macaques without decreasing the lifespan of productively infected cells

PLoS pathogens, 2010-01, Vol.6 (1), p.e1000747-e1000747

2010

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CTLA-4+PD-1− Memory CD4+ T Cells Critically Contribute to Viral Persistence in Antiretroviral Therapy-Suppressed, SIV-Infected Rhesus Macaques

Immunity (Cambridge, Mass.), 2017-10, Vol.47 (4), p.776-788.e5

2017

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Nonhuman primate models of human viral infections

Pathobiology of HIV/SIV-associated changes in secondary lymphoid tissues

Increased intestinal permeability correlates with sigmoid mucosa alpha-synuclein staining and endotoxin exposure markers in early Parkinson's disease

Initiation of ART during early acute HIV infection preserves mucosal Th17 function and reverses HIV-related immune activation

Vascular Disease and Thrombosis in SARS-CoV-2-Infected Rhesus Macaques

Genetically-barcoded SIV facilitates enumeration of rebound variants and estimation of reactivation rates in nonhuman primates following interruption of suppressive antiretroviral therapy

Damaged intestinal epithelial integrity linked to microbial translocation in pathogenic simian immunodeficiency virus infections

B cell follicle sanctuary permits persistent productive simian immunodeficiency virus infection in elite controllers

Robust and persistent reactivation of SIV and HIV by N-803 and depletion of CD8 + cells

CD8+ Lymphocytes Are Required for Maintaining Viral Suppression in SIV-Infected Macaques Treated with Short-Term Antiretroviral Therapy

Tissue Myeloid Cells in SIV-Infected Primates Acquire Viral DNA through Phagocytosis of Infected T Cells

In-depth virological and immunological characterization of HIV-1 cure after CCR5Δ32/Δ32 allogeneic hematopoietic stem cell transplantation

Treatment with native heterodimeric IL-15 increases cytotoxic lymphocytes and reduces SHIV RNA in lymph nodes

African green monkeys avoid SIV disease progression by preventing intestinal dysfunction and maintaining mucosal barrier integrity

The human IL-15 superagonist N-803 promotes migration of virus-specific CD8+ T and NK cells to B cell follicles but does not reverse latency in ART-suppressed, SHIV-infected macaques

Systemic administration of antiretrovirals prior to exposure prevents rectal and intravenous HIV-1 transmission in humanized BLT mice

Large number of rebounding/founder HIV variants emerge from multifocal infection in lymphatic tissues after treatment interruption

Ad26.COV2.S prevents upregulation of SARS-CoV-2 induced pathways of inflammation and thrombosis in hamsters and rhesus macaques

Differential impact of transplantation on peripheral and tissue-associated viral reservoirs: Implications for HIV gene therapy

CD4 depletion in SIV-infected macaques results in macrophage and microglia infection with rapid turnover of infected cells

Defining total-body AIDS-virus burden with implications for curative strategies

Next-generation in situ hybridization approaches to define and quantify HIV and SIV reservoirs in tissue microenvironments

Intrahepatic CXCL10 is strongly associated with liver fibrosis in HIV-Hepatitis B co-infection

CD8+ lymphocytes control viral replication in SIVmac239-infected rhesus macaques without decreasing the lifespan of productively infected cells

CTLA-4+PD-1− Memory CD4+ T Cells Critically Contribute to Viral Persistence in Antiretroviral Therapy-Suppressed, SIV-Infected Rhesus Macaques

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