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Dibenzocyclooctynes: Effect of Aryl Substitution on Their Reactivity toward Strain-Promoted Alkyne–Azide Cycloaddition

Journal of organic chemistry, 2019-07, Vol.84 (13), p.8542-8551

2019

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Chemodivergent, Tunable, and Selective Iodine(III)-Mediated Bromo-Functionalizations of Polyprenoids

Organic letters, 2017-09, Vol.19 (18), p.4766-4769

2017

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Discovery of a New Class of Protein Farnesyltransferase Inhibitors in the Arylthiophene Series

Journal of medicinal chemistry, 2009-10, Vol.52 (20), p.6205-6208

2009

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Isocombretastatins A versus Combretastatins A: The Forgotten isoCA-4 Isomer as a Highly Promising Cytotoxic and Antitubulin Agent

Journal of medicinal chemistry, 2009-07, Vol.52 (14), p.4538-4542

2009

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Mallotojaponins B and C: Total Synthesis, Antiparasitic Evaluation, and Preliminary SAR Studies

Organic letters, 2016-02, Vol.18 (4), p.708-711

2016

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Synthesis of polysubstituted benzofuran derivatives as novel inhibitors of parasitic growth

Bioorganic & medicinal chemistry, 2013-09, Vol.21 (17), p.4885-4892

2013

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One-Pot Synthesis of 2‑Styrylindoles from Ortho-Substituted Chloroenynes

Journal of organic chemistry, 2018-12, Vol.83 (24), p.15323-15332

2018

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First Total Synthesis of Original Chalcone–Flavone Dimers as Cissampeloflavone Analogues

European journal of organic chemistry, 2018-11, Vol.2018 (42), p.5843-5852

2018

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Phenothiazine- and Carbazole-Cyanochalcones as Dual Inhibitors of Tubulin Polymerization and Human Farnesyltransferase

Pharmaceuticals (Basel, Switzerland), 2023-06, Vol.16 (6), p.888

2023

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Ultrasounds-mediated 10-seconds synthesis of chalcones as potential farnesyltransferase inhibitors

Bioorganic & medicinal chemistry letters, 2020-06, Vol.30 (11), p.127149-127149, Article 127149

2020

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Iodine(III)-mediated halogenations of acyclic monoterpenoids

Beilstein journal of organic chemistry, 2018-05, Vol.14 (1), p.1103-1111

2018

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Design, synthesis and anticancer properties of IsoCombretaQuinolines as potent tubulin assembly inhibitors

European journal of medicinal chemistry, 2017-02, Vol.127, p.1025-1034

2017

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Design and Synthesis of Tubulin and Histone Deacetylase Inhibitor Based on iso-Combretastatin A‑4

Journal of medicinal chemistry, 2018-08, Vol.61 (15), p.6574-6591

2018

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On the discovery of new potent human farnesyltransferase inhibitors: emerging pyroglutamic derivatives

Organic & biomolecular chemistry, 2017-10, Vol.15 (38), p.8110-8118

2017

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Enhanced antitumor potential induced by chloroacetate-loaded benzophenones acting as fused tubulin-pyruvate dehydrogenase kinase 1 (PDHK1) ligands

Bioorganic chemistry, 2020-03, Vol.96, p.103643-103643, Article 103643

2020

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1,1-Diheterocyclic Ethylenes Derived from Quinaldine and Carbazole as New Tubulin-Polymerization Inhibitors: Synthesis, Metabolism, and Biological Evaluation

Journal of medicinal chemistry, 2019-02, Vol.62 (4), p.1902-1916

2019

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Indolizine-phenothiazine hybrids as the first dual inhibitors of tubulin polymerization and farnesyltransferase with synergistic antitumor activity

Bioorganic chemistry, 2020-10, Vol.103, p.104184-104184, Article 104184

2020

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Discovery of indolizines containing triazine moiety as new leads for the development of antitumoral agents targeting mitotic events

Bioorganic & medicinal chemistry letters, 2015-09, Vol.25 (18), p.3975-3979

2015

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Discovery of azaisoerianin derivatives as potential antitumors agents

European journal of medicinal chemistry, 2014-05, Vol.78, p.178-189

2014

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N,N-bis-heteroaryl methylamines: Potent anti-mitotic and highly cytotoxic agents

European journal of medicinal chemistry, 2019-04, Vol.168, p.176-188

2019

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Studies on indolizines. Evaluation of their biological properties as microtubule-interacting agents and as melanoma targeting compounds

European journal of medicinal chemistry, 2015-01, Vol.89, p.115-127

2015

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Synthesis of a 3‑(α-Styryl)benzo[b]‑thiophene Library via Bromocyclization of Alkynes and Palladium-Catalyzed Tosylhydrazones Cross-Couplings: Evaluation as Antitubulin Agents

ACS combinatorial science, 2014-12, Vol.16 (12), p.702-710

2014

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Novel indolizine derivatives with unprecedented inhibitory activity on human farnesyltransferase

Bioorganic & medicinal chemistry letters, 2014-12, Vol.24 (24), p.5777-5781

2014

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Semisynthesis of Natural Flavones Inhibiting Tubulin Polymerization, from Hesperidin

Journal of natural products (Washington, D.C.), 2010-04, Vol.73 (4), p.702-706

2010

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Access to 3-spiroindolizines containing an isoindole ring through intra-molecular arylation of spiro-N-acyliminium species: a new family of potent farnesyltransferase inhibitors

Organic & biomolecular chemistry, 2019-03, Vol.17 (10), p.2798-2808

2019

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Dibenzocyclooctynes: Effect of Aryl Substitution on Their Reactivity toward Strain-Promoted Alkyne–Azide Cycloaddition

Chemodivergent, Tunable, and Selective Iodine(III)-Mediated Bromo-Functionalizations of Polyprenoids

Discovery of a New Class of Protein Farnesyltransferase Inhibitors in the Arylthiophene Series

Isocombretastatins A versus Combretastatins A: The Forgotten isoCA-4 Isomer as a Highly Promising Cytotoxic and Antitubulin Agent

Mallotojaponins B and C: Total Synthesis, Antiparasitic Evaluation, and Preliminary SAR Studies

Synthesis of polysubstituted benzofuran derivatives as novel inhibitors of parasitic growth

One-Pot Synthesis of 2‑Styrylindoles from Ortho-Substituted Chloroenynes

First Total Synthesis of Original Chalcone–Flavone Dimers as Cissampeloflavone Analogues

Phenothiazine- and Carbazole-Cyanochalcones as Dual Inhibitors of Tubulin Polymerization and Human Farnesyltransferase

Ultrasounds-mediated 10-seconds synthesis of chalcones as potential farnesyltransferase inhibitors

Iodine(III)-mediated halogenations of acyclic monoterpenoids

Design, synthesis and anticancer properties of IsoCombretaQuinolines as potent tubulin assembly inhibitors

Design and Synthesis of Tubulin and Histone Deacetylase Inhibitor Based on iso-Combretastatin A‑4

On the discovery of new potent human farnesyltransferase inhibitors: emerging pyroglutamic derivatives

Enhanced antitumor potential induced by chloroacetate-loaded benzophenones acting as fused tubulin-pyruvate dehydrogenase kinase 1 (PDHK1) ligands

1,1-Diheterocyclic Ethylenes Derived from Quinaldine and Carbazole as New Tubulin-Polymerization Inhibitors: Synthesis, Metabolism, and Biological Evaluation

Indolizine-phenothiazine hybrids as the first dual inhibitors of tubulin polymerization and farnesyltransferase with synergistic antitumor activity

Discovery of indolizines containing triazine moiety as new leads for the development of antitumoral agents targeting mitotic events

Discovery of azaisoerianin derivatives as potential antitumors agents

N,N-bis-heteroaryl methylamines: Potent anti-mitotic and highly cytotoxic agents

Studies on indolizines. Evaluation of their biological properties as microtubule-interacting agents and as melanoma targeting compounds

Synthesis of a 3‑(α-Styryl)benzo[b]‑thiophene Library via Bromocyclization of Alkynes and Palladium-Catalyzed Tosylhydrazones Cross-Couplings: Evaluation as Antitubulin Agents

Novel indolizine derivatives with unprecedented inhibitory activity on human farnesyltransferase

Semisynthesis of Natural Flavones Inhibiting Tubulin Polymerization, from Hesperidin

Access to 3-spiroindolizines containing an isoindole ring through intra-molecular arylation of spiro-N-acyliminium species: a new family of potent farnesyltransferase inhibitors

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