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Intracellular Neutrophil Oxidants: From Laboratory Curiosity to Clinical Reality

The Journal of immunology (1950), 2019-06, Vol.202 (11), p.3127-3134

2019

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The allosterically modulated FFAR2 is transactivated by signals generated by other neutrophil GPCRs

PloS one, 2023-04, Vol.18 (4)

2023

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The allosterically modulated FFAR2 is transactivated by signals generated by other neutrophil GPCRs

PloS one, 2023-04, Vol.18 (4), p.e0268363-e0268363

2023

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Neutrophil NET formation is regulated from the inside by myeloperoxidase-processed reactive oxygen species

Free radical biology & medicine, 2015-12, Vol.89, p.1024-1035

2015

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Intracellular generation of superoxide by the phagocyte NADPH oxidase: How, where, and what for?

Free radical biology & medicine, 2010-12, Vol.49 (12), p.1834-1845

2010

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International Union of Basic and Clinical Pharmacology. LXXIII. Nomenclature for the formyl peptide receptor (FPR) family

Pharmacological reviews, 2009-06, Vol.61 (2), p.119

2009

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Mitocryptides from Human Mitochondrial DNA-Encoded Proteins Activate Neutrophil Formyl Peptide Receptors: Receptor Preference and Signaling Properties

The Journal of immunology (1950), 2018-05, Vol.200 (9), p.3269-3282

2018

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Receptor-Dependent and -Independent Immunomodulatory Effects of Phenol-Soluble Modulin Peptides from Staphylococcus aureus on Human Neutrophils Are Abrogated through Peptide Inactivation by Reactive Oxygen Species

Infection and Immunity, 2012-06, Vol.80 (6), p.1987-1995

2012

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Measurement of respiratory burst products, released or retained, during activation of professional phagocytes

Methods in molecular biology (Clifton, N.J.), 2014-01, Vol.1124, p.321

2014

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Formation, Signaling and Occurrence of Specialized Pro-Resolving Lipid Mediators-What is the Evidence so far?

Frontiers in pharmacology, 2022-03, Vol.13, p.838782

2022

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The human neutrophil subsets defined by the presence or absence of OLFM4 both transmigrate into tissue in vivo and give rise to distinct NETs in vitro

PloS one, 2013-07, Vol.8 (7), p.e69575-e69575

2013

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Identification of Residues Critical for FPR2 Activation by the Cryptic Peptide Mitocryptide-2 Originating from the Mitochondrial DNA-Encoded Cytochrome b

The Journal of immunology (1950), 2019-05, Vol.202 (9), p.2710-2719

2019

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A pepducin derived from the third intracellular loop of FPR2 is a partial agonist for direct activation of this receptor in neutrophils but a full agonist for cross-talk triggered reactivation of FPR2

PloS one, 2014-10, Vol.9 (10), p.e109516-e109516

2014

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Reactivation of Gαi‐coupled formyl peptide receptors is inhibited by Gαq‐selective inhibitors when induced by signals generated by the platelet‐activating factor receptor

Journal of leukocyte biology, 2017-09, Vol.102 (3), p.871-880

2017

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Host defense peptide LL-37 selectively reduces proinflammatory macrophage responses

The Journal of immunology (1950), 2011-05, Vol.186 (9), p.5497-5505

2011

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Elevated Mitochondrial Reactive Oxygen Species and Cellular Redox Imbalance in Human NADPH-Oxidase-Deficient Phagocytes

Frontiers in immunology, 2017-12, Vol.8, p.1828-1828

2017

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Formyl peptide derived lipopeptides disclose differences between the receptors in mouse and men and call the pepducin concept in question

PloS one, 2017-09, Vol.12 (9), p.e0185132-e0185132

2017

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Reactivation of desensitized formyl peptide receptors by platelet activating factor: a novel receptor cross talk mechanism regulating neutrophil superoxide anion production

PloS one, 2013-03, Vol.8 (3), p.e60169

2013

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Ligand recognition and activation of formyl peptide receptors in neutrophils

Journal of leukocyte biology, 2006-02, Vol.79 (2), p.247-256

2006

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Formylated MHC Class Ib Binding Peptides Activate Both Human and Mouse Neutrophils Primarily through Formyl Peptide Receptor 1

PloS one, 2016-12, Vol.11 (12), p.e0167529-e0167529

2016

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Porphyromonas gingivalis Produce Neutrophil Specific Chemoattractants Including Short Chain Fatty Acids

Frontiers in cellular and infection microbiology, 2021-01, Vol.10, p.620681-620681

2021

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Structural characterization and inhibitory profile of formyl peptide receptor 2 selective peptides descending from a PIP2-binding domain of gelsolin

The Journal of immunology (1950), 2012-07, Vol.189 (2), p.629-637

2012

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Data showing effects of a PI3K-δ inhibitor on neutrophil superoxide production during FPR2 activation and reactivation

Data in brief, 2020-10, Vol.32, p.106185-106185, Article 106185

2020

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Measurement of respiratory burst products generated by professional phagocytes

Methods in molecular biology (Clifton, N.J.), 2007, Vol.412, p.349

2007

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The FPR2-induced rise in cytosolic calcium in human neutrophils relies on an emptying of intracellular calcium stores and is inhibited by a gelsolin-derived PIP2-binding peptide

BMC Cell Biology, 2010-07, Vol.11, p.52-52

2010

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Intracellular Neutrophil Oxidants: From Laboratory Curiosity to Clinical Reality

The allosterically modulated FFAR2 is transactivated by signals generated by other neutrophil GPCRs

The allosterically modulated FFAR2 is transactivated by signals generated by other neutrophil GPCRs

Neutrophil NET formation is regulated from the inside by myeloperoxidase-processed reactive oxygen species

Intracellular generation of superoxide by the phagocyte NADPH oxidase: How, where, and what for?

International Union of Basic and Clinical Pharmacology. LXXIII. Nomenclature for the formyl peptide receptor (FPR) family

Mitocryptides from Human Mitochondrial DNA-Encoded Proteins Activate Neutrophil Formyl Peptide Receptors: Receptor Preference and Signaling Properties

Receptor-Dependent and -Independent Immunomodulatory Effects of Phenol-Soluble Modulin Peptides from Staphylococcus aureus on Human Neutrophils Are Abrogated through Peptide Inactivation by Reactive Oxygen Species

Measurement of respiratory burst products, released or retained, during activation of professional phagocytes

Formation, Signaling and Occurrence of Specialized Pro-Resolving Lipid Mediators-What is the Evidence so far?

The human neutrophil subsets defined by the presence or absence of OLFM4 both transmigrate into tissue in vivo and give rise to distinct NETs in vitro

Identification of Residues Critical for FPR2 Activation by the Cryptic Peptide Mitocryptide-2 Originating from the Mitochondrial DNA-Encoded Cytochrome b

A pepducin derived from the third intracellular loop of FPR2 is a partial agonist for direct activation of this receptor in neutrophils but a full agonist for cross-talk triggered reactivation of FPR2

Reactivation of Gαi‐coupled formyl peptide receptors is inhibited by Gαq‐selective inhibitors when induced by signals generated by the platelet‐activating factor receptor

Host defense peptide LL-37 selectively reduces proinflammatory macrophage responses

Elevated Mitochondrial Reactive Oxygen Species and Cellular Redox Imbalance in Human NADPH-Oxidase-Deficient Phagocytes

Formyl peptide derived lipopeptides disclose differences between the receptors in mouse and men and call the pepducin concept in question

Reactivation of desensitized formyl peptide receptors by platelet activating factor: a novel receptor cross talk mechanism regulating neutrophil superoxide anion production

Ligand recognition and activation of formyl peptide receptors in neutrophils

Formylated MHC Class Ib Binding Peptides Activate Both Human and Mouse Neutrophils Primarily through Formyl Peptide Receptor 1

Porphyromonas gingivalis Produce Neutrophil Specific Chemoattractants Including Short Chain Fatty Acids

Structural characterization and inhibitory profile of formyl peptide receptor 2 selective peptides descending from a PIP2-binding domain of gelsolin

Data showing effects of a PI3K-δ inhibitor on neutrophil superoxide production during FPR2 activation and reactivation

Measurement of respiratory burst products generated by professional phagocytes

The FPR2-induced rise in cytosolic calcium in human neutrophils relies on an emptying of intracellular calcium stores and is inhibited by a gelsolin-derived PIP2-binding peptide

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