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The allosterically modulated FFAR2 is transactivated by signals generated by other neutrophil GPCRs

PloS one, 2023-04, Vol.18 (4)

2023

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The allosterically modulated FFAR2 is transactivated by signals generated by other neutrophil GPCRs

PloS one, 2023-04, Vol.18 (4), p.e0268363-e0268363

2023

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International Union of Basic and Clinical Pharmacology. LXXIII. Nomenclature for the formyl peptide receptor (FPR) family

Pharmacological reviews, 2009-06, Vol.61 (2), p.119

2009

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Receptor-Dependent and -Independent Immunomodulatory Effects of Phenol-Soluble Modulin Peptides from Staphylococcus aureus on Human Neutrophils Are Abrogated through Peptide Inactivation by Reactive Oxygen Species

Infection and Immunity, 2012-06, Vol.80 (6), p.1987-1995

2012

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Formation, Signaling and Occurrence of Specialized Pro-Resolving Lipid Mediators-What is the Evidence so far?

Frontiers in pharmacology, 2022-03, Vol.13, p.838782

2022

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The human neutrophil subsets defined by the presence or absence of OLFM4 both transmigrate into tissue in vivo and give rise to distinct NETs in vitro

PloS one, 2013-07, Vol.8 (7), p.e69575-e69575

2013

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Mitocryptides from Human Mitochondrial DNA-Encoded Proteins Activate Neutrophil Formyl Peptide Receptors: Receptor Preference and Signaling Properties

The Journal of immunology (1950), 2018-05, Vol.200 (9), p.3269-3282

2018

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A pepducin derived from the third intracellular loop of FPR2 is a partial agonist for direct activation of this receptor in neutrophils but a full agonist for cross-talk triggered reactivation of FPR2

PloS one, 2014-10, Vol.9 (10), p.e109516-e109516

2014

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Reactivation of Gαi‐coupled formyl peptide receptors is inhibited by Gαq‐selective inhibitors when induced by signals generated by the platelet‐activating factor receptor

Journal of leukocyte biology, 2017-09, Vol.102 (3), p.871-880

2017

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Elevated Mitochondrial Reactive Oxygen Species and Cellular Redox Imbalance in Human NADPH-Oxidase-Deficient Phagocytes

Frontiers in immunology, 2017-12, Vol.8, p.1828-1828

2017

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Formyl peptide derived lipopeptides disclose differences between the receptors in mouse and men and call the pepducin concept in question

PloS one, 2017-09, Vol.12 (9), p.e0185132-e0185132

2017

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Reactivation of desensitized formyl peptide receptors by platelet activating factor: a novel receptor cross talk mechanism regulating neutrophil superoxide anion production

PloS one, 2013-03, Vol.8 (3), p.e60169

2013

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Formylated MHC Class Ib Binding Peptides Activate Both Human and Mouse Neutrophils Primarily through Formyl Peptide Receptor 1

PloS one, 2016-12, Vol.11 (12), p.e0167529-e0167529

2016

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Porphyromonas gingivalis Produce Neutrophil Specific Chemoattractants Including Short Chain Fatty Acids

Frontiers in cellular and infection microbiology, 2021-01, Vol.10, p.620681-620681

2021

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Pneumolysin Released during Streptococcus pneumoniae Autolysis Is a Potent Activator of Intracellular Oxygen Radical Production in Neutrophils

Infection and Immunity, 2008-09, Vol.76 (9), p.4079-4087

2008

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Data showing effects of a PI3K-δ inhibitor on neutrophil superoxide production during FPR2 activation and reactivation

Data in brief, 2020-10, Vol.32, p.106185-106185, Article 106185

2020

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The FPR2-induced rise in cytosolic calcium in human neutrophils relies on an emptying of intracellular calcium stores and is inhibited by a gelsolin-derived PIP2-binding peptide

BMC Cell Biology, 2010-07, Vol.11, p.52-52

2010

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Intracellular Neutrophil Oxidants: From Laboratory Curiosity to Clinical Reality

The Journal of immunology (1950), 2019-06, Vol.202 (11), p.3127-3134

2019

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Functional characteristics of circulating granulocytes in severe congenital neutropenia caused by ELANE mutations

BMC pediatrics, 2019-06, Vol.19 (1), p.189-189, Article 189

2019

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Phenol-soluble modulin α and β display divergent roles in mice with staphylococcal septic arthritis

Communications biology, 2022-09, Vol.5 (1), p.910-910, Article 910

2022

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Structure–Function Characteristics and Signaling Properties of Lipidated Peptidomimetic FPR2 Agonists: Peptoid Stereochemistry and Residues in the Vicinity of the Headgroup Affect Function

ACS omega, 2019-03, Vol.4 (3), p.5968-5982

2019

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In vivo-transmigrated human neutrophils are resistant to antiapoptotic stimulation

Journal of leukocyte biology, 2011-12, Vol.90 (6), p.1055-1063

2011

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The Synthetic Peptide Trp-Lys-Tyr-Met-Val-Met-NH2 Specifically Activates Neutrophils through FPRL1/Lipoxin A4 Receptors and Is an Agonist for the Orphan Monocyte-expressed Chemoattractant Receptor FPRL2

The Journal of biological chemistry, 2001-06, Vol.276 (24), p.21585-21593

2001

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Data on human neutrophil activation induced by pepducins with amino acid sequences derived from β2AR and CXCR4

Data in brief, 2016-09, Vol.8, p.411-414

2016

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Quantification of heterotypic granule fusion in human neutrophils by imaging flow cytometry

Data in brief, 2016-03, Vol.6, p.386-393

2016

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The allosterically modulated FFAR2 is transactivated by signals generated by other neutrophil GPCRs

The allosterically modulated FFAR2 is transactivated by signals generated by other neutrophil GPCRs

International Union of Basic and Clinical Pharmacology. LXXIII. Nomenclature for the formyl peptide receptor (FPR) family

Receptor-Dependent and -Independent Immunomodulatory Effects of Phenol-Soluble Modulin Peptides from Staphylococcus aureus on Human Neutrophils Are Abrogated through Peptide Inactivation by Reactive Oxygen Species

Formation, Signaling and Occurrence of Specialized Pro-Resolving Lipid Mediators-What is the Evidence so far?

The human neutrophil subsets defined by the presence or absence of OLFM4 both transmigrate into tissue in vivo and give rise to distinct NETs in vitro

Mitocryptides from Human Mitochondrial DNA-Encoded Proteins Activate Neutrophil Formyl Peptide Receptors: Receptor Preference and Signaling Properties

A pepducin derived from the third intracellular loop of FPR2 is a partial agonist for direct activation of this receptor in neutrophils but a full agonist for cross-talk triggered reactivation of FPR2

Reactivation of Gαi‐coupled formyl peptide receptors is inhibited by Gαq‐selective inhibitors when induced by signals generated by the platelet‐activating factor receptor

Elevated Mitochondrial Reactive Oxygen Species and Cellular Redox Imbalance in Human NADPH-Oxidase-Deficient Phagocytes

Formyl peptide derived lipopeptides disclose differences between the receptors in mouse and men and call the pepducin concept in question

Reactivation of desensitized formyl peptide receptors by platelet activating factor: a novel receptor cross talk mechanism regulating neutrophil superoxide anion production

Formylated MHC Class Ib Binding Peptides Activate Both Human and Mouse Neutrophils Primarily through Formyl Peptide Receptor 1

Porphyromonas gingivalis Produce Neutrophil Specific Chemoattractants Including Short Chain Fatty Acids

Pneumolysin Released during Streptococcus pneumoniae Autolysis Is a Potent Activator of Intracellular Oxygen Radical Production in Neutrophils

Data showing effects of a PI3K-δ inhibitor on neutrophil superoxide production during FPR2 activation and reactivation

The FPR2-induced rise in cytosolic calcium in human neutrophils relies on an emptying of intracellular calcium stores and is inhibited by a gelsolin-derived PIP2-binding peptide

Intracellular Neutrophil Oxidants: From Laboratory Curiosity to Clinical Reality

Functional characteristics of circulating granulocytes in severe congenital neutropenia caused by ELANE mutations

Phenol-soluble modulin α and β display divergent roles in mice with staphylococcal septic arthritis

Structure–Function Characteristics and Signaling Properties of Lipidated Peptidomimetic FPR2 Agonists: Peptoid Stereochemistry and Residues in the Vicinity of the Headgroup Affect Function

In vivo-transmigrated human neutrophils are resistant to antiapoptotic stimulation

The Synthetic Peptide Trp-Lys-Tyr-Met-Val-Met-NH2 Specifically Activates Neutrophils through FPRL1/Lipoxin A4 Receptors and Is an Agonist for the Orphan Monocyte-expressed Chemoattractant Receptor FPRL2

Data on human neutrophil activation induced by pepducins with amino acid sequences derived from β2AR and CXCR4

Quantification of heterotypic granule fusion in human neutrophils by imaging flow cytometry

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