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Novel and shared neoantigen derived from histone 3 variant H3.3K27M mutation for glioma T cell therapy

The Journal of experimental medicine, 2018-01, Vol.215 (1), p.141-157

2018

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Macrophages: Regulators of the Inflammatory Microenvironment during Mammary Gland Development and Breast Cancer

Mediators of inflammation, 2016-01, Vol.2016, p.4549676-13

2016

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Deep immune profiling reveals targetable mechanisms of immune evasion in immune checkpoint inhibitor-refractory glioblastoma

Journal for immunotherapy of cancer, 2021-06, Vol.9 (6), p.e002181

2021

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Semaphorin 4A is dynamically regulated during thymocyte development in mice

Cellular immunology, 2013-02, Vol.281 (2), p.150-158

2013

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IMMU-52. LOW-INTENSITY PULSED ULTRASOUND CONDUCTS ANTIGEN-INDEPENDENT T CELL HOMING INTO THE BRAIN PARENCHYMA WITH THE INTACT BLOOD-BRAIN BARRIER

Neuro-oncology (Charlottesville, Va.), 2023-11, Vol.25 (Supplement_5), p.v154-v154

2023

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EXTH-06. PRE-INFUSION METABOLIC MODULATION OF CAR-T CELLS PROMOTES THE RESISTANCE TO THE SUPPRESSIVE EFFECTS OF HYPOXIA AND ENHANCES ANTI-TUMOR EFFECTS AGAINST INTRACEREBRAL GLIOMAS

Neuro-oncology (Charlottesville, Va.), 2022-11, Vol.24 (Supplement_7), p.vii209-vii210

2022

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Abstract P4-04-05: Contributions of STAT3 to pro-tumorigenic alterations within the microenvironment during mammary tumorigenesis

Cancer research (Chicago, Ill.), 2015-05, Vol.75 (9_Supplement), p.P4-P4-04-05

2015

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JAK/STAT inhibition in macrophages promotes therapeutic resistance by inducing expression of protumorigenic factors

Proceedings of the National Academy of Sciences - PNAS, 2019-06, Vol.116 (25), p.12442-12451

2019

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EXTH-34. LOCAL DELIVERY OF AN IL-15 SUPERAGONIST USING A REPLICATING RETROVIRUS SYNGERIZES WITH TEMOZOLOMIDE TO INCREASE LYMPHOCYTE INFILTRATION AND SURVIVAL IN TWO POORLY IMMUNOGENIC GLIOBLASTOMA MOUSE MODELS

Neuro-oncology (Charlottesville, Va.), 2023-11, Vol.25 (Supplement_5), p.v231-v231

2023

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EXTH-18. DEVELOPMENT OF A TRANSGENIC MOUSE MODEL ENABLING COMPARATIVE ANALYSIS OF CHIMERIC ANTIGEN RECEPTOR (CAR)-EXPRESSING IMMUNE CELL POPULATIONS FOR CANCER IMMUNOTHERAPY

Neuro-oncology (Charlottesville, Va.), 2023-11, Vol.25 (Supplement_5), p.v227-v227

2023

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IMMU-21. LOW-INTENSITY PULSED ULTRASOUND PROMOTES THE PRESENTATION OF BRAIN-DERIVED ANTIGENS THROUGH ENHANCED TRAFFICKING OF ANTIGEN-PRESENTING CELLS FROM THE BRAIN INTO THE PERIPHERY

Neuro-oncology (Charlottesville, Va.), 2023-11, Vol.25 (Supplement_5), p.v146-v146

2023

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Unique challenges for glioblastoma immunotherapy—discussions across neuro-oncology and non-neuro-oncology experts in cancer immunology. Meeting Report from the 2019 SNO Immuno-Oncology Think Tank

Neuro-oncology (Charlottesville, Va.), 2021-03, Vol.23 (3), p.356-375

2021

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Local Delivery of a Novel Combination Immunotherapy Increases T Cell Infiltration and Significantly Improves Survival in a Poorly Immunogenic Model of Glioblastoma

Neurosurgery, 2020-12, Vol.67 (Supplement_1)

2020

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IMMU-04. OVERCOMING IMMUNE EVASION IN GLIOBLASTOMA

Neuro-oncology (Charlottesville, Va.), 2018-11, Vol.20 (suppl_6), p.vi121-vi122

2018

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Abstract 1774: Pre-treatment of CAR-T cells with met+rap improves the mitochondrial function and anti-tumor efficacy in a hypoxic glioma microenvironment

Cancer research (Chicago, Ill.), 2023-04, Vol.83 (7_Supplement), p.1774-1774

2023

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Novel EGFRvIII-CAR transgenic mice for rigorous preclinical studies in syngeneic mice

Neuro-oncology (Charlottesville, Va.), 2022-02, Vol.24 (2), p.259-272

2022

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Enhancing CAR-T cell metabolism to overcome hypoxic conditions in the brain tumor microenvironment

JCI insight, 2024-04, Vol.9 (7)

2024

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Activation of the FGFR―STAT3 Pathway in Breast Cancer Cells Induces a Hyaluronan-Rich Microenvironment That Licenses Tumor Formation

Cancer research (Chicago, Ill.), 2014-01, Vol.74 (1), p.374-386

2014

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Abstract A37: Activation of FGFR1 signaling in mammary tumors leads to STAT3 activation and chemoresistance

Cancer research (Chicago, Ill.), 2013-02, Vol.73 (3_Supplement), p.A37-A37

2013

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Abstract B84: Activation of the STAT3 pathway leads to a hyaluronan-rich microenvironment that promotes breast cancer growth and therapeutic resistance

Cancer research (Chicago, Ill.), 2015-01, Vol.75 (1_Supplement), p.B84-B84

2015

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Epiregulin contributes to breast tumorigenesis through regulating matrix metalloproteinase 1 and promoting cell survival

Molecular cancer, 2015-07, Vol.14 (1), p.138-138, Article 138

2015

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Inhibition of D-2HG leads to upregulation of a proinflammatory gene signature in a novel HLA-A2/HLA-DR1 transgenic mouse model of IDH1R132H-expressing glioma

Journal for immunotherapy of cancer, 2022-05, Vol.10 (5), p.e004644

2022

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IMMU-42. ONO-AE3-208 PROMOTES ANTI-TUMOR IMMUNE ACTIVITY AND SURVIVAL IN GLIOMA MODELS

Neuro-oncology (Charlottesville, Va.), 2017-11, Vol.19 (suppl_6), p.vi122-vi122

2017

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The FGF/FGF receptor axis as a therapeutic target in breast cancer

Expert Review of Endocrinology & Metabolism, 2013-07, Vol.8 (4), p.391-402

2013

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IMMU-41. H3.3K27M MUTATION-DERIVED NOVEL NEOANTIGEN – CHARACTERIZATION OF THE HLA-A2-BINDING EPITOPE AND A SPECIFIC T CELL RECEPTOR FOR DEVELOPMENT OF T CELL-BASED IMMUNOTHERAPY

Neuro-oncology (Charlottesville, Va.), 2017-11, Vol.19 (suppl_6), p.vi121-vi121

2017

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Novel and shared neoantigen derived from histone 3 variant H3.3K27M mutation for glioma T cell therapy

Macrophages: Regulators of the Inflammatory Microenvironment during Mammary Gland Development and Breast Cancer

Deep immune profiling reveals targetable mechanisms of immune evasion in immune checkpoint inhibitor-refractory glioblastoma

Semaphorin 4A is dynamically regulated during thymocyte development in mice

IMMU-52. LOW-INTENSITY PULSED ULTRASOUND CONDUCTS ANTIGEN-INDEPENDENT T CELL HOMING INTO THE BRAIN PARENCHYMA WITH THE INTACT BLOOD-BRAIN BARRIER

EXTH-06. PRE-INFUSION METABOLIC MODULATION OF CAR-T CELLS PROMOTES THE RESISTANCE TO THE SUPPRESSIVE EFFECTS OF HYPOXIA AND ENHANCES ANTI-TUMOR EFFECTS AGAINST INTRACEREBRAL GLIOMAS

Abstract P4-04-05: Contributions of STAT3 to pro-tumorigenic alterations within the microenvironment during mammary tumorigenesis

JAK/STAT inhibition in macrophages promotes therapeutic resistance by inducing expression of protumorigenic factors

EXTH-34. LOCAL DELIVERY OF AN IL-15 SUPERAGONIST USING A REPLICATING RETROVIRUS SYNGERIZES WITH TEMOZOLOMIDE TO INCREASE LYMPHOCYTE INFILTRATION AND SURVIVAL IN TWO POORLY IMMUNOGENIC GLIOBLASTOMA MOUSE MODELS

EXTH-18. DEVELOPMENT OF A TRANSGENIC MOUSE MODEL ENABLING COMPARATIVE ANALYSIS OF CHIMERIC ANTIGEN RECEPTOR (CAR)-EXPRESSING IMMUNE CELL POPULATIONS FOR CANCER IMMUNOTHERAPY

IMMU-21. LOW-INTENSITY PULSED ULTRASOUND PROMOTES THE PRESENTATION OF BRAIN-DERIVED ANTIGENS THROUGH ENHANCED TRAFFICKING OF ANTIGEN-PRESENTING CELLS FROM THE BRAIN INTO THE PERIPHERY

Unique challenges for glioblastoma immunotherapy—discussions across neuro-oncology and non-neuro-oncology experts in cancer immunology. Meeting Report from the 2019 SNO Immuno-Oncology Think Tank

Local Delivery of a Novel Combination Immunotherapy Increases T Cell Infiltration and Significantly Improves Survival in a Poorly Immunogenic Model of Glioblastoma

IMMU-04. OVERCOMING IMMUNE EVASION IN GLIOBLASTOMA

Abstract 1774: Pre-treatment of CAR-T cells with met+rap improves the mitochondrial function and anti-tumor efficacy in a hypoxic glioma microenvironment

Novel EGFRvIII-CAR transgenic mice for rigorous preclinical studies in syngeneic mice

Enhancing CAR-T cell metabolism to overcome hypoxic conditions in the brain tumor microenvironment

Activation of the FGFR―STAT3 Pathway in Breast Cancer Cells Induces a Hyaluronan-Rich Microenvironment That Licenses Tumor Formation

Abstract A37: Activation of FGFR1 signaling in mammary tumors leads to STAT3 activation and chemoresistance

Abstract B84: Activation of the STAT3 pathway leads to a hyaluronan-rich microenvironment that promotes breast cancer growth and therapeutic resistance

Epiregulin contributes to breast tumorigenesis through regulating matrix metalloproteinase 1 and promoting cell survival

Inhibition of D-2HG leads to upregulation of a proinflammatory gene signature in a novel HLA-A2/HLA-DR1 transgenic mouse model of IDH1R132H-expressing glioma

IMMU-42. ONO-AE3-208 PROMOTES ANTI-TUMOR IMMUNE ACTIVITY AND SURVIVAL IN GLIOMA MODELS

The FGF/FGF receptor axis as a therapeutic target in breast cancer

IMMU-41. H3.3K27M MUTATION-DERIVED NOVEL NEOANTIGEN – CHARACTERIZATION OF THE HLA-A2-BINDING EPITOPE AND A SPECIFIC T CELL RECEPTOR FOR DEVELOPMENT OF T CELL-BASED IMMUNOTHERAPY

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