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The pro- and anti-inflammatory properties of the cytokine interleukin-6

Biochimica et biophysica acta, 2011-05, Vol.1813 (5), p.878-888

2011

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ADAM17: a molecular switch to control inflammation and tissue regeneration

Trends in immunology, 2011-08, Vol.32 (8), p.380-387

2011

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The soluble Interleukin 6 receptor: Generation and role in inflammation and cancer

European journal of cell biology, 2011-06, Vol.90 (6), p.484-494

2011

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Mechanistic insights into a TIMP3-sensitive pathway constitutively engaged in the regulation of cerebral hemodynamics

eLife, 2016-08, Vol.5

2016

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Species Specificity of ADAM10 and ADAM17 Proteins in Interleukin-6 (IL-6) Trans-signaling and Novel Role of ADAM10 in Inducible IL-6 Receptor Shedding

The Journal of biological chemistry, 2011-04, Vol.286 (17), p.14804-14811

2011

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Critical role of the disintegrin metalloprotease ADAM17 for intestinal inflammation and regeneration in mice

The Journal of experimental medicine, 2010-08, Vol.207 (8), p.1617-1624

2010

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Apoptosis is a natural stimulus of IL6R shedding and contributes to the proinflammatory trans-signaling function of neutrophils

Blood, 2007-09, Vol.110 (6), p.1748-1755

2007

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G Protein-Coupled Receptor 43 Is Essential for Neutrophil Recruitment during Intestinal Inflammation

The Journal of immunology (1950), 2009-12, Vol.183 (11), p.7514-7522

2009

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A Disintegrin and Metalloprotease 17 Dynamic Interaction Sequence, the Sweet Tooth for the Human Interleukin 6 Receptor

The Journal of biological chemistry, 2014-06, Vol.289 (23), p.16336-16348

2014

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Epithelial RNase H2 Maintains Genome Integrity and Prevents Intestinal Tumorigenesis in Mice

Gastroenterology (New York, N.Y. 1943), 2019-01, Vol.156 (1), p.145-159.e19

2019

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Transgenic blockade of interleukin 6 transsignaling abrogates inflammation

Blood, 2008-02, Vol.111 (3), p.1021-1028

2008

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Selective blockade of interleukin-6 trans-signaling improves survival in a murine polymicrobial sepsis model

Critical care medicine, 2011-06, Vol.39 (6), p.1407-1413

2011

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Differentially regulated GPVI ectodomain shedding by multiple platelet–expressed proteinases

Blood, 2010-10, Vol.116 (17), p.3347-3355

2010

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Senescence‐associated release of transmembrane proteins involves proteolytic processing by ADAM17 and microvesicle shedding

The FASEB journal, 2014-11, Vol.28 (11), p.4847-4856

2014

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Mouse neutrophils express the decoy type 2 interleukin-1 receptor (IL-1R2) constitutively and in acute inflammatory conditions

Journal of leukocyte biology, 2013-10, Vol.94 (4), p.791-802

2013

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ADAM17: molekularer Schalter zwischen Entzündung und Regeneration

Biospektrum, 2011-09, Vol.17 (5), p.506-509

2011

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The role of metalloproteinase ADAM17 in regulating ICOS ligand-mediated humoral immune responses

The Journal of immunology (1950), 2014-09, Vol.193 (6), p.2753-2763

2014

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TP53 co-mutations in EGFR mutated patients in NSCLC stage IV: A strong predictive factor of ORR, PFS and OS in EGFR mt+ NSCLC

Oncotarget, 2020-01, Vol.11 (3), p.250-264

2020

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Structure-guided Optimization of the Interleukin-6 Trans-signaling Antagonist sgp130

The Journal of biological chemistry, 2008-10, Vol.283 (40), p.27200-27207

2008

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N-Linked Glycosylation Is Essential for the Stability but Not the Signaling Function of the Interleukin-6 Signal Transducer Glycoprotein 130

The Journal of biological chemistry, 2010-01, Vol.285 (3), p.1781-1789

2010

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Transglutaminase-catalyzed covalent multimerization of camelidae anti-human TNF single domain antibodies improves neutralizing activity

Journal of biotechnology, 2009-06, Vol.142 (2), p.170-178

2009

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Absence of RNase H2 triggers generation of immunogenic micronuclei removed by autophagy

Human molecular genetics, 2017-10, Vol.26 (20), p.3960-3972

2017

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Different Soluble Forms of the Interleukin-6 Family Signal Transducer gp130 Fine-tune the Blockade of Interleukin-6 Trans-signaling

The Journal of biological chemistry, 2016-07, Vol.291 (31), p.16186-16196

2016

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Shedding of Endogenous Interleukin-6 Receptor (IL-6R) Is Governed by A Disintegrin and Metalloproteinase (ADAM) Proteases while a Full-length IL-6R Isoform Localizes to Circulating Microvesicles

The Journal of biological chemistry, 2015-10, Vol.290 (43), p.26059-26071

2015

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The pro- and anti-inflammatory properties of the cytokine interleukin-6

ADAM17: a molecular switch to control inflammation and tissue regeneration

The soluble Interleukin 6 receptor: Generation and role in inflammation and cancer

Mechanistic insights into a TIMP3-sensitive pathway constitutively engaged in the regulation of cerebral hemodynamics

STAT3 regulated ARF expression suppresses prostate cancer metastasis

Species Specificity of ADAM10 and ADAM17 Proteins in Interleukin-6 (IL-6) Trans-signaling and Novel Role of ADAM10 in Inducible IL-6 Receptor Shedding

Critical role of the disintegrin metalloprotease ADAM17 for intestinal inflammation and regeneration in mice

Apoptosis is a natural stimulus of IL6R shedding and contributes to the proinflammatory trans-signaling function of neutrophils

G Protein-Coupled Receptor 43 Is Essential for Neutrophil Recruitment during Intestinal Inflammation

A Disintegrin and Metalloprotease 17 Dynamic Interaction Sequence, the Sweet Tooth for the Human Interleukin 6 Receptor

Epithelial RNase H2 Maintains Genome Integrity and Prevents Intestinal Tumorigenesis in Mice

Transgenic blockade of interleukin 6 transsignaling abrogates inflammation

Selective blockade of interleukin-6 trans-signaling improves survival in a murine polymicrobial sepsis model

Differentially regulated GPVI ectodomain shedding by multiple platelet–expressed proteinases

Senescence‐associated release of transmembrane proteins involves proteolytic processing by ADAM17 and microvesicle shedding

Mouse neutrophils express the decoy type 2 interleukin-1 receptor (IL-1R2) constitutively and in acute inflammatory conditions

ADAM17: molekularer Schalter zwischen Entzündung und Regeneration

The role of metalloproteinase ADAM17 in regulating ICOS ligand-mediated humoral immune responses

TP53 co-mutations in EGFR mutated patients in NSCLC stage IV: A strong predictive factor of ORR, PFS and OS in EGFR mt+ NSCLC

Structure-guided Optimization of the Interleukin-6 Trans-signaling Antagonist sgp130

N-Linked Glycosylation Is Essential for the Stability but Not the Signaling Function of the Interleukin-6 Signal Transducer Glycoprotein 130

Transglutaminase-catalyzed covalent multimerization of camelidae anti-human TNF single domain antibodies improves neutralizing activity

Absence of RNase H2 triggers generation of immunogenic micronuclei removed by autophagy

Different Soluble Forms of the Interleukin-6 Family Signal Transducer gp130 Fine-tune the Blockade of Interleukin-6 Trans-signaling

Shedding of Endogenous Interleukin-6 Receptor (IL-6R) Is Governed by A Disintegrin and Metalloproteinase (ADAM) Proteases while a Full-length IL-6R Isoform Localizes to Circulating Microvesicles

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