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Next-Generation Hedgehog/GLI Pathway Inhibitors for Cancer Therapy

Cancers, 2019-04, Vol.11 (4), p.538

2019

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Hedgehog/GLI signaling in tumor immunity - new therapeutic opportunities and clinical implications

Cell communication and signaling, 2019-12, Vol.17 (1), p.172-172, Article 172

2019

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Organoids for Modeling (Colorectal) Cancer in a Dish

Cancers, 2022-11, Vol.14 (21), p.5416

2022

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From inflammation to gastric cancer - the importance of Hedgehog/GLI signaling in Helicobacter pylori-induced chronic inflammatory and neoplastic diseases

Cell communication and signaling, 2017-04, Vol.15 (1), p.15-15, Article 15

2017

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Opioids drive breast cancer metastasis through the δ-opioid receptor and oncogenic STAT3

Neoplasia (New York, N.Y.), 2021-02, Vol.23 (2), p.270-279

2021

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Context-dependent modulation of aggressiveness of pediatric tumors by individual oncogenic RAS isoforms

Oncogene, 2021-08, Vol.40 (31), p.4955-4966

2021

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Hedgehog/GLI signaling in hematopoietic development and acute myeloid leukemia—From bench to bedside

Frontiers in cell and developmental biology, 2022-08, Vol.10, p.944760-944760

2022

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Epidermal activation of Hedgehog signaling establishes an immunosuppressive microenvironment in basal cell carcinoma by modulating skin immunity

Molecular oncology, 2020-09, Vol.14 (9), p.1930-1946

2020

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Helicobacter pylori induces a novel form of innate immune memory via accumulation of NF-кB proteins

Frontiers in immunology, 2023, Vol.14, p.1290833-1290833

2023

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Understanding cell signaling in cancer stem cells for targeted therapy - can phosphoproteomics help to reveal the secrets?

Cell communication and signaling, 2017-03, Vol.15 (1), p.12-12, Article 12

2017

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Selective Modulation of Hedgehog/GLI Target Gene Expression by Epidermal Growth Factor Signaling in Human Keratinocytes

Molecular and Cellular Biology, 2006-08, Vol.26 (16), p.6283-6298

2006

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The sound of tumor cell-microenvironment communication - composed by the Cancer Cluster Salzburg research network

Cell communication and signaling, 2017-06, Vol.15 (1), p.20-20, Article 20

2017

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Casein Kinase 1D Encodes a Novel Drug Target in Hedgehog—GLI-Driven Cancers and Tumor-Initiating Cells Resistant to SMO Inhibition

Cancers, 2021-08, Vol.13 (16), p.4227

2021

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Phosphoproteomics of short-term hedgehog signaling in human medulloblastoma cells

Cell communication and signaling, 2020-06, Vol.18 (1), p.99-18, Article 99

2020

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Context-dependent signal integration by the GLI code: The oncogenic load, pathways, modifiers and implications for cancer therapy

Seminars in cell & developmental biology, 2014-09, Vol.33 (100), p.93-104

2014

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Proteins and Molecular Pathways Relevant for the Malignant Properties of Tumor-Initiating Pancreatic Cancer Cells

Cells (Basel, Switzerland), 2020-06, Vol.9 (6), p.1397

2020

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Human GLI2 and GLI1 are part of a positive feedback mechanism in basal cell carcinoma

Oncogene, 2002-08, Vol.21 (36), p.5529-5539

2002

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Lung Adenocarcinomas and Lung Cancer Cell Lines Show Association of MMP-1 Expression With STAT3 Activation

Translational oncology, 2015-04, Vol.8 (2), p.97-105

2015

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Next-Generation Hedgehog/GLI Pathway Inhibitors for Cancer Therapy

Hedgehog/GLI signaling in tumor immunity - new therapeutic opportunities and clinical implications

Organoids for Modeling (Colorectal) Cancer in a Dish

From inflammation to gastric cancer - the importance of Hedgehog/GLI signaling in Helicobacter pylori-induced chronic inflammatory and neoplastic diseases

STAT3 promotes melanoma metastasis by CEBP-induced repression of the MITF pathway

Opioids drive breast cancer metastasis through the δ-opioid receptor and oncogenic STAT3

Dependency on the TYK2/STAT1/MCL1 axis in anaplastic large cell lymphoma

Context-dependent modulation of aggressiveness of pediatric tumors by individual oncogenic RAS isoforms

STAT3‐dependent analysis reveals PDK4 as independent predictor of recurrence in prostate cancer

CD44 engagement enhances acute myeloid leukemia cell adhesion to the bone marrow microenvironment by increasing VLA-4 avidity

Hedgehog/GLI signaling in hematopoietic development and acute myeloid leukemia—From bench to bedside

Synergism between Hedgehog-GLI and EGFR signaling in Hedgehog-responsive human medulloblastoma cells induces downregulation of canonical Hedgehog-target genes and stabilized expression of GLI1

Epidermal activation of Hedgehog signaling establishes an immunosuppressive microenvironment in basal cell carcinoma by modulating skin immunity

Helicobacter pylori induces a novel form of innate immune memory via accumulation of NF-кB proteins

Understanding cell signaling in cancer stem cells for targeted therapy - can phosphoproteomics help to reveal the secrets?

Selective Modulation of Hedgehog/GLI Target Gene Expression by Epidermal Growth Factor Signaling in Human Keratinocytes

The sound of tumor cell-microenvironment communication - composed by the Cancer Cluster Salzburg research network

Casein Kinase 1D Encodes a Novel Drug Target in Hedgehog—GLI-Driven Cancers and Tumor-Initiating Cells Resistant to SMO Inhibition

Correction: Dependency on the TYK2/STAT1/MCL1 axis in anaplastic large cell lymphoma

The Class IIA Histone Deacetylase (HDAC) Inhibitor TMP269 Downregulates Ribosomal Proteins and Has Anti-Proliferative and Pro-Apoptotic Effects on AML Cells

Phosphoproteomics of short-term hedgehog signaling in human medulloblastoma cells

Context-dependent signal integration by the GLI code: The oncogenic load, pathways, modifiers and implications for cancer therapy

Proteins and Molecular Pathways Relevant for the Malignant Properties of Tumor-Initiating Pancreatic Cancer Cells

Human GLI2 and GLI1 are part of a positive feedback mechanism in basal cell carcinoma

Lung Adenocarcinomas and Lung Cancer Cell Lines Show Association of MMP-1 Expression With STAT3 Activation

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