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Structural Requirements of Transmembrane Domain 3 for Activation by the M1 Muscarinic Receptor Agonists AC-42, AC-260584, Clozapine, and N-Desmethylclozapine: Evidence for Three Distinct Modes of Receptor Activation

Molecular pharmacology, 2006-12, Vol.70 (6), p.1974-1983

2006

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ACP-103, a 5-hydroxytryptamine 2A receptor inverse agonist, improves the antipsychotic efficacy and side-effect profile of haloperidol and risperidone in experimental models

The Journal of pharmacology and experimental therapeutics, 2007-08, Vol.322 (2), p.862

2007

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Characterization of the Mas‐related gene family: structural and functional conservation of human and rhesus MrgX receptors

British journal of pharmacology, 2006-01, Vol.147 (1), p.73-82

2006

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Broad modulation of neuropathic pain states by a selective estrogen receptor beta agonist

European journal of pharmacology, 2008-08, Vol.590 (1), p.423-429

2008

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Discovery of a Potent, Orally Available, and Isoform-Selective Retinoic Acid β2 Receptor Agonist

Journal of medicinal chemistry, 2005-12, Vol.48 (24), p.7517-7519

2005

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Constitutively Active Mutants of the Histamine H1 Receptor Suggest a Conserved Hydrophobic Asparagine-Cage That Constrains the Activation of Class A G Protein-Coupled Receptors

Molecular pharmacology, 2008-01, Vol.73 (1), p.94

2008

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Identification of novel subtype selective RAR agonists

Biochemical pharmacology, 2005-12, Vol.71 (1), p.156-162

2005

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Monitoring Interactions between Receptor Tyrosine Kinases and Their Downstream Effector Proteins in Living Cells Using Bioluminescence Resonance Energy Transfer

Molecular pharmacology, 2007-12, Vol.72 (6), p.1440-1446

2007

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Pharmacology and Signaling Properties of Epidermal Growth Factor Receptor Isoforms Studied by Bioluminescence Resonance Energy Transfer

Molecular pharmacology, 2007-02, Vol.71 (2), p.508-518

2007

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Loss-of-Function Polymorphic Variants of the Human Angiotensin II Type 1 Receptor

Molecular pharmacology, 2004-03, Vol.65 (3), p.770-777

2004

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Identification of the Atypical L-Type Ca2+ Channel Blocker Diltiazem and Its Metabolites As Ghrelin Receptor Agonists

Molecular pharmacology, 2007-08, Vol.72 (2), p.380-386

2007

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Pharmacological characterization of AC-90179 [2-(4-methoxyphenyl)-N-(4-methyl-benzyl)-N-(1-methyl-piperidin-4-yl)-acetamide hydrochloride]: a selective serotonin 2A receptor inverse agonist

The Journal of pharmacology and experimental therapeutics, 2004-09, Vol.310 (3), p.943

2004

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Dopamine D2 Receptor Dimers and Receptor-Blocking Peptides

Biochemical and biophysical research communications, 1996-10, Vol.227 (1), p.200-204

1996

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The Second Intracellular Loop of the m5 Muscarinic Receptor Is the Switch Which Enables G-protein Coupling

The Journal of biological chemistry, 1998-09, Vol.273 (38), p.24322-24327

1998

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Differential modulation of inflammatory pain by a selective estrogen receptor beta agonist

European journal of pharmacology, 2008-09, Vol.592 (1), p.158-159

2008

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PET analysis of the 5-HT2A receptor inverse agonist ACP-103 in human brain

The international journal of neuropsychopharmacology, 2008-03, Vol.11 (2), p.163-171

2008

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Integrative functional assays, chemical genomics and high throughput screening: harnessing signal transduction pathways to a common HTS readout

Current pharmaceutical design, 2006-05, Vol.12 (14), p.1717

2006

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Molecular Biology of G-Protein-Coupled Receptors

1, 1992

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Diurnal Expression of Transducin mRNA and Translocation of Transducin in Rods of Rat Retina

Science (American Association for the Advancement of Science), 1987-01, Vol.235 (4788), p.585-587

1987

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Discovery of the First Nonpeptide Agonist of the GPR14/Urotensin-II Receptor: 3-(4-Chlorophenyl)-3-(2- (dimethylamino)ethyl)isochroman-1-one (AC-7954)

Journal of medicinal chemistry, 2002-11, Vol.45 (23), p.4950-4953

2002

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Identification of a Ligand-dependent Switch within a Muscarinic Receptor

The Journal of biological chemistry, 1998-08, Vol.273 (34), p.21563-21568

1998

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Pharmacology of muscarinic acetylcholine receptor subtypes (m1–m5): high throughput assays in mammalian cells

European journal of pharmacology, 1996-01, Vol.295 (1), p.93-102

1996

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Human dopamine D1 receptor encoded by an intronless gene on chromosome 5

Nature (London), 1990-09, Vol.347 (6288), p.80-83

1990

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Identification of novel selective v2 receptor non-peptide agonists

Biochemical pharmacology, 2008-10, Vol.76 (9), p.1134-1141

2008

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Pharmacology of polymorphic variants of the human 5-HT1A receptor

Biochemical pharmacology, 2004-02, Vol.67 (3), p.479-490

2004

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Structural Requirements of Transmembrane Domain 3 for Activation by the M1 Muscarinic Receptor Agonists AC-42, AC-260584, Clozapine, and N-Desmethylclozapine: Evidence for Three Distinct Modes of Receptor Activation

ACP-103, a 5-hydroxytryptamine 2A receptor inverse agonist, improves the antipsychotic efficacy and side-effect profile of haloperidol and risperidone in experimental models

Characterization of the Mas‐related gene family: structural and functional conservation of human and rhesus MrgX receptors

Broad modulation of neuropathic pain states by a selective estrogen receptor beta agonist

Discovery of a Potent, Orally Available, and Isoform-Selective Retinoic Acid β2 Receptor Agonist

Constitutively Active Mutants of the Histamine H1 Receptor Suggest a Conserved Hydrophobic Asparagine-Cage That Constrains the Activation of Class A G Protein-Coupled Receptors

Identification of novel subtype selective RAR agonists

Monitoring Interactions between Receptor Tyrosine Kinases and Their Downstream Effector Proteins in Living Cells Using Bioluminescence Resonance Energy Transfer

Pharmacology and Signaling Properties of Epidermal Growth Factor Receptor Isoforms Studied by Bioluminescence Resonance Energy Transfer

Loss-of-Function Polymorphic Variants of the Human Angiotensin II Type 1 Receptor

Identification of the Atypical L-Type Ca2+ Channel Blocker Diltiazem and Its Metabolites As Ghrelin Receptor Agonists

Pharmacological characterization of AC-90179 [2-(4-methoxyphenyl)-N-(4-methyl-benzyl)-N-(1-methyl-piperidin-4-yl)-acetamide hydrochloride]: a selective serotonin 2A receptor inverse agonist

Dopamine D2 Receptor Dimers and Receptor-Blocking Peptides

The Second Intracellular Loop of the m5 Muscarinic Receptor Is the Switch Which Enables G-protein Coupling

Differential modulation of inflammatory pain by a selective estrogen receptor beta agonist

PET analysis of the 5-HT2A receptor inverse agonist ACP-103 in human brain

Integrative functional assays, chemical genomics and high throughput screening: harnessing signal transduction pathways to a common HTS readout

Molecular Biology of G-Protein-Coupled Receptors

Diurnal Expression of Transducin mRNA and Translocation of Transducin in Rods of Rat Retina

Discovery of the First Nonpeptide Agonist of the GPR14/Urotensin-II Receptor: 3-(4-Chlorophenyl)-3-(2- (dimethylamino)ethyl)isochroman-1-one (AC-7954)

Identification of a Ligand-dependent Switch within a Muscarinic Receptor

Pharmacology of muscarinic acetylcholine receptor subtypes (m1–m5): high throughput assays in mammalian cells

Human dopamine D1 receptor encoded by an intronless gene on chromosome 5

Identification of novel selective v2 receptor non-peptide agonists

Pharmacology of polymorphic variants of the human 5-HT1A receptor

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