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Protein recognition by a pattern-generating fluorescent molecular probe

Nature nanotechnology, 2017-12, Vol.12 (12), p.1161-1168

2017

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Rapid Covalent-Probe Discovery by Electrophile-Fragment Screening

Journal of the American Chemical Society, 2019-06, Vol.141 (22), p.8951-8968

2019

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Ubiquitous selection for mecA in community-associated MRSA across diverse chemical environments

Nature communications, 2020-11, Vol.11 (1), p.6038-6038, Article 6038

2020

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Site-Specific Labeling of Endogenous Proteins Using CoLDR Chemistry

Journal of the American Chemical Society, 2021-12, Vol.143 (48), p.20095-20108

2021

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An automatic pipeline for the design of irreversible derivatives identifies a potent SARS-CoV-2 Mpro inhibitor

Cell chemical biology, 2021-12, Vol.28 (12), p.1795-1806.e5

2021

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Small molecule inhibitor of Igf2bp1 represses Kras and a pro-oncogenic phenotype in cancer cells

RNA biology, 2022-12, Vol.19 (1), p.26-43

2022

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Azapeptide activity-based probes for the SARS-CoV-2 main protease enable visualization of inhibition in infected cells

Chemical science (Cambridge), 2023-02, Vol.14 (7), p.1666-1672

2023

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The E3 Ubiquitin-Ligase Bmi1/Ring1A Controls the Proteasomal Degradation of Top2α Cleavage Complex – A Potentially New Drug Target

PloS one, 2009-12, Vol.4 (12), p.e8104

2009

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A generic, cost-effective, and scalable cell lineage analysis platform

Genome research, 2016-11, Vol.26 (11), p.1588

2016

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High content image analysis reveals function of miR-124 upstream of Vimentin in regulating motor neuron mitochondria

Scientific reports, 2018-01, Vol.8 (1), p.59-59, Article 59

2018

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Specific quinone reductase 2 inhibitors reduce metabolic burden and reverse Alzheimer's disease phenotype in mice

The Journal of clinical investigation, 2023-10, Vol.133 (19), p.1-16

2023

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Dasatinib response in acute myeloid leukemia is correlated with FLT3/ITD, PTPN11 mutations and a unique gene expression signature

Haematologica (Roma), 2020-12, Vol.105 (12), p.2795-2804

2020

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A multiplexed screening method for pluripotency

Stem cell research, 2017-08, Vol.23 (C), p.158-162

2017

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Identification of a Promising Drug Candidate for the Treatment of Type 2 Diabetes Based on a P2Y1 Receptor Agonist

Journal of medicinal chemistry, 2012-09, Vol.55 (17), p.7623-7635

2012

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Identification of a promising drug candidate for the treatment of type 2 diabetes based on a P2Y(1) receptor agonist

Journal of medicinal chemistry, 2012-09, Vol.55 (17), p.7623-7635

2012

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Targeting SRSF2 mutations in leukemia with RKI-1447: A strategy to impair cellular division and nuclear structure

iScience, 2024-04, Vol.27 (4), p.109443-109443, Article 109443

2024

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A Novel Insulin Secretagogue Based on a Dinucleoside Polyphosphate Scaffold

Journal of medicinal chemistry, 2010-03, Vol.53 (6), p.2472-2481

2010

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Non-quaternary oximes detoxify nerve agents and reactivate nerve agent-inhibited human butyrylcholinesterase

Communications biology, 2021-05, Vol.4 (1), p.573-8, Article 573

2021

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The Trans-Golgi Network-Associated Human Ubiquitin-Protein Ligase POSH Is Essential for HIV Type 1 Production

Proceedings of the National Academy of Sciences - PNAS, 2005-02, Vol.102 (5), p.1478-1483

2005

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Induction of Apoptosis by Adenovirus E4orf4 Protein Is Specific to Transformed Cells and Requires an Interaction with Protein Phosphatase 2A

Proceedings of the National Academy of Sciences - PNAS, 1999-08, Vol.96 (18), p.10080-10085

1999

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Structural basis for producing selective MAP2K7 inhibitors

Bioorganic & medicinal chemistry letters, 2020-11, Vol.30 (22), p.127546-127546, Article 127546

2020

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Efficient maternal to neonatal transfer of antibodies against SARS-CoV-2 and BNT162b2 mRNA COVID-19 vaccine

The Journal of clinical investigation, 2021-07, Vol.131 (13), p.1-9

2021

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Pan-cancer single-cell RNA-seq identifies recurring programs of cellular heterogeneity

Nature genetics, 2020-11, Vol.52 (11), p.1208-1218

2020

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Induce the endogenous tumor suppressor miR-34a by small molecules to inhibit liver metastasis

Journal of hepatology, 2022-07, Vol.77, p.S387

2022

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Protein recognition by a pattern-generating fluorescent molecular probe

Rapid Covalent-Probe Discovery by Electrophile-Fragment Screening

Ubiquitous selection for mecA in community-associated MRSA across diverse chemical environments

Site-Specific Labeling of Endogenous Proteins Using CoLDR Chemistry

An automatic pipeline for the design of irreversible derivatives identifies a potent SARS-CoV-2 Mpro inhibitor

Small molecule inhibitor of Igf2bp1 represses Kras and a pro-oncogenic phenotype in cancer cells

Azapeptide activity-based probes for the SARS-CoV-2 main protease enable visualization of inhibition in infected cells

The E3 Ubiquitin-Ligase Bmi1/Ring1A Controls the Proteasomal Degradation of Top2α Cleavage Complex – A Potentially New Drug Target

A generic, cost-effective, and scalable cell lineage analysis platform

High content image analysis reveals function of miR-124 upstream of Vimentin in regulating motor neuron mitochondria

Specific quinone reductase 2 inhibitors reduce metabolic burden and reverse Alzheimer's disease phenotype in mice

Dasatinib response in acute myeloid leukemia is correlated with FLT3/ITD, PTPN11 mutations and a unique gene expression signature

Synaptojanin 2 is a druggable mediator of metastasis and the gene is overexpressed and amplified in breast cancer

A multiplexed screening method for pluripotency

Identification of a Promising Drug Candidate for the Treatment of Type 2 Diabetes Based on a P2Y1 Receptor Agonist

Identification of a promising drug candidate for the treatment of type 2 diabetes based on a P2Y(1) receptor agonist

Targeting SRSF2 mutations in leukemia with RKI-1447: A strategy to impair cellular division and nuclear structure

A Novel Insulin Secretagogue Based on a Dinucleoside Polyphosphate Scaffold

Non-quaternary oximes detoxify nerve agents and reactivate nerve agent-inhibited human butyrylcholinesterase

The Trans-Golgi Network-Associated Human Ubiquitin-Protein Ligase POSH Is Essential for HIV Type 1 Production

Induction of Apoptosis by Adenovirus E4orf4 Protein Is Specific to Transformed Cells and Requires an Interaction with Protein Phosphatase 2A

Structural basis for producing selective MAP2K7 inhibitors

Efficient maternal to neonatal transfer of antibodies against SARS-CoV-2 and BNT162b2 mRNA COVID-19 vaccine

Pan-cancer single-cell RNA-seq identifies recurring programs of cellular heterogeneity

Induce the endogenous tumor suppressor miR-34a by small molecules to inhibit liver metastasis

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